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Laparoscopic vs Open Distal Gastrectomy for Locally Advanced Gastric Cancer: 5-Year Outcomes of the KLASS-02 Randomized Clinical Trial.
Son SY, Hur H, Hyung WJ, Park YK, Lee HJ, An JY, Kim W, Kim HI, Kim HH, Ryu SW, Kim MC, Kong SH, Cho GS, Kim JJ, Park DJ, Ryu KW, Kim YW, Kim JW, Lee JH, Yang HK, Han SU; Korean Laparoendoscopic Gastrointestinal Surgery Study (KLASS) Group. Son SY, et al. JAMA Surg. 2022 Oct 1;157(10):879-886. doi: 10.1001/jamasurg.2022.2749. JAMA Surg. 2022. PMID: 35857305 Free PMC article.
mRNA-HPV vaccine encoding E6 and E7 improves therapeutic potential for HPV-mediated cancers via subcutaneous immunization.
Lee S, Yoon H, Hong SH, Kwon SP, Hong JJ, Kwak HW, Park HJ, Yoo S, Bae SH, Park HJ, Lee J, Bang YJ, Lee YS, Kim JY, Yoon S, Roh G, Cho Y, Kim Y, Kim D, Park SI, Kim DH, Lee S, Oh A, Ha D, Lee SY, Park M, Hwang EH, Bae G, Jeon E, Park SH, Choi WS, Oh HR, Kim IW, Youn H, Keum G, Bang EK, Rhee JH, Lee SE, Nam JH. Lee S, et al. J Med Virol. 2023 Dec;95(12):e29309. doi: 10.1002/jmv.29309. J Med Virol. 2023. PMID: 38100632
Alendronate/cRGD-Decorated Ultrafine Hyaluronate Dot Targeting Bone Metastasis.
Lee E, Park J, Youn YS, Oh KT, Kim D, Lee ES. Lee E, et al. Biomedicines. 2020 Nov 11;8(11):492. doi: 10.3390/biomedicines8110492. Biomedicines. 2020. PMID: 33187133 Free PMC article.
These dots thus prepared (10 nm in diameter) enabled extensive cellular interactions such as hyaluronate (HA)-mediated CD44 receptor binding, ALN-mediated bone targeting, and cRGD-mediated tumor integrin alpha(v)beta(3) binding, thus improving their tumor targeting efficie …
These dots thus prepared (10 nm in diameter) enabled extensive cellular interactions such as hyaluronate (HA)-mediated CD44 receptor …
Hyaluronated nanoparticles with pH- and enzyme-responsive drug release properties.
Kim SW, Oh KT, Youn YS, Lee ES. Kim SW, et al. Colloids Surf B Biointerfaces. 2014 Apr 1;116:359-64. doi: 10.1016/j.colsurfb.2014.01.017. Epub 2014 Jan 23. Colloids Surf B Biointerfaces. 2014. PMID: 24521699
In this study, we report the development of a novel pH-responsive nanoparticle composed of hyaluronic acid (HA) grafted with functional 3-diethylaminopropyl (DEAP) groups (HA-g-DEAP). ...HA-g-DEAP was prepared by a simple conjugation of the carboxylic acid gr …
In this study, we report the development of a novel pH-responsive nanoparticle composed of hyaluronic acid (HA) grafted with function …
Improvement of moss photosynthesis by humic acids from Antarctic tundra soil.
Byun MY, Kim D, Youn UJ, Lee S, Lee H. Byun MY, et al. Plant Physiol Biochem. 2021 Feb;159:37-42. doi: 10.1016/j.plaphy.2020.12.007. Epub 2020 Dec 9. Plant Physiol Biochem. 2021. PMID: 33321376
There have been several published reports regarding the growth promoting effect of humic acids (HA) on vascular plants; however, the effect of HA on bryophytes is still unknown. ...Spectroscopic structural properties of KS1-3_HA were characterized and determi …
There have been several published reports regarding the growth promoting effect of humic acids (HA) on vascular plants; however, the …
Tumor-Homing pH-Sensitive Extracellular Vesicles for Targeting Heterogeneous Tumors.
Park J, Lee H, Youn YS, Oh KT, Lee ES. Park J, et al. Pharmaceutics. 2020 Apr 17;12(4):372. doi: 10.3390/pharmaceutics12040372. Pharmaceutics. 2020. PMID: 32316679 Free PMC article.
Furthermore, the hydrophobic HDEA present in HDEA@EVs at pH 7.4 can switch to hydrophilic HDEA at pH 6.5 as a result of acidic pH-induced protonation of 3-(diethylamino)propylamine (DEAP) moieties, resulting in an acidic pH-activated EVs' disruption, accelerated release of encaps …
Furthermore, the hydrophobic HDEA present in HDEA@EVs at pH 7.4 can switch to hydrophilic HDEA at pH 6.5 as a result of acidic pH-induced pr …
Cyclic RGD-Conjugated Hyaluronate Dot Bearing Cleavable Doxorubicin for Multivalent Tumor Targeting.
Noh GJ, Oh KT, Youn YS, Lee ES. Noh GJ, et al. Biomacromolecules. 2020 Jun 8;21(6):2525-2535. doi: 10.1021/acs.biomac.0c00554. Epub 2020 May 20. Biomacromolecules. 2020. PMID: 32384236
In this study, we developed an extremely small-sized water-soluble hyaluronate dot (dHA) conjugated with cyclic RGD (cRGD) and cleavable doxorubicin (DOX, as a model antitumor drug), named cRGD@dHA-c-DOX. This dot with HA moieties (as specific ligands to tumor CD44 recepto …
In this study, we developed an extremely small-sized water-soluble hyaluronate dot (dHA) conjugated with cyclic RGD (cRGD) and cleavable dox …
Assessing the impact of mRNA vaccination in chronic inflammatory murine model.
Lee S, Lee J, Cho SH, Roh G, Park HJ, Lee YJ, Jeon HE, Lee YS, Bae SH, Youn SB, Cho Y, Oh A, Ha D, Lee SY, Choi EJ, Cho S, Lee S, Kim DH, Kang MH, Yoon MS, Lim BK, Nam JH. Lee S, et al. NPJ Vaccines. 2024 Feb 15;9(1):34. doi: 10.1038/s41541-024-00825-z. NPJ Vaccines. 2024. PMID: 38360752 Free PMC article.
23 results