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The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione.
Murae M, Shimizu Y, Yamamoto Y, Kobayashi A, Houri M, Inoue T, Irie T, Gemba R, Kondo Y, Nakano Y, Miyazaki S, Yamada D, Saitoh A, Ishii I, Onodera T, Takahashi Y, Wakita T, Fukasawa M, Noguchi K. Murae M, et al. Among authors: kondo y. Biochem Biophys Res Commun. 2022 Mar 15;597:30-36. doi: 10.1016/j.bbrc.2022.01.106. Epub 2022 Jan 29. Biochem Biophys Res Commun. 2022. PMID: 35123263 Free PMC article.
Does castration status affect docetaxel-related adverse events? :Identification of risk factors for docetaxel-related adverse events in metastatic prostate cancer.
Yanagisawa T, Kimura T, Hata K, Narita S, Hatakeyama S, Enei Y, Atsuta M, Mori K, Obayashi K, Yoshihara K, Kondo Y, Oguchi T, Sadakane I, Habuchi T, Ohyama C, Shariat SF, Egawa S. Yanagisawa T, et al. Among authors: kondo y. Prostate. 2022 Oct;82(14):1322-1330. doi: 10.1002/pros.24406. Epub 2022 Jun 29. Prostate. 2022. PMID: 35767376
Exposure of the cryptic de-adhesive site FNIII14 in fibronectin molecule and its binding to membrane-type eEF1A induce migration and invasion of cancer cells via β1-integrin inactivation.
Itagaki K, Sasada M, Miyazaki S, Iyoda T, Imaizumi T, Haga M, Kuga A, Inomata H, Kondo Y, Osada S, Kodama H, Higami Y, Fukai F. Itagaki K, et al. Among authors: kondo y. Am J Cancer Res. 2020 Nov 1;10(11):3990-4004. eCollection 2020. Am J Cancer Res. 2020. PMID: 33294281 Free PMC article.