Multiplexing metasurfaces have drawn great interest from the microwave to optical regimes. However, previous works often encounter the restriction of insufficient independence and deficient interference suppression among different channels. Herein, a metasurface platform featuring a dual-wavelength and dual-polarization multiplexing operation is proposed for highly decorrelated and completely independent manipulation of four frequency and polarization states. As illustrative examples, two paradigms of a multiplexing holographic metasurface in which four channels can respond independently without conjugate images are presented, and the measurement results not only validate the feasibility but also exhibit excellent imaging efficiency. The proposed metasurface may thus boost more complex and versatile multi-functional devices.