Background: This study explores the responses of the cardiovascular system as humans exercise in an oxygen-enriched room at high altitude under various concentrations of CO₂.
Methods: The study utilized a hypobaric chamber set to the following specifications: 3800 m altitude with 25% O₂ and different CO₂ concentrations of 0.5% (C1), 3.0% (C2) and 5.0% (C3). Subjects exercised for 3 min three times, separated by 30 min resting periods in the above-mentioned conditions, at sea level (SL) and at 3800 m altitude (HA). The changes of heart rate variability, heart rate and blood pressure were analyzed.
Results: Total power (TP) and high frequency power (HF) decreased notably during post-exercise at HA. HF increased prominently earlier the post-exercise period at 3800 m altitude with 25% O₂ and 5.0% CO₂ (C3), while low frequency power (LF) changed barely in all tests. The ratios of LF/HF were significantly higher during post-exercise in HA, and lower after high intensity exercise in C3. Heart rate and systolic blood pressure increased significantly in HA and C3.
Conclusions: Parasympathetic activity dominated in cardiac autonomic modulation, and heart rate and blood pressure increased significantly after high intensity exercise in C3.
Keywords: blood pressure; cardiac autonomic modulation; exercise; heart rate; heart rate variability.