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Quantification of the Time Course of CYP3A Inhibition, Activation, and Induction Using a Population Pharmacokinetic Model of Microdosed Midazolam Continuous Infusion.
Nassar YM, Hohmann N, Michelet R, Gottwalt K, Meid AD, Burhenne J, Huisinga W, Haefeli WE, Mikus G, Kloft C. Nassar YM, et al. Clin Pharmacokinet. 2022 Nov;61(11):1595-1607. doi: 10.1007/s40262-022-01175-6. Epub 2022 Oct 4. Clin Pharmacokinet. 2022. PMID: 36195807 Free PMC article. Clinical Trial.
A prognostic baseline blood biomarker and tumor growth kinetics integrated model in paclitaxel/platinum treated advanced non-small cell lung cancer patients.
Ojara FW, Henrich A, Frances N, Nassar YM, Huisinga W, Hartung N, Geiger K, Holdenrieder S, Joerger M, Kloft C. Ojara FW, et al. Among authors: nassar ym. CPT Pharmacometrics Syst Pharmacol. 2023 Nov;12(11):1714-1725. doi: 10.1002/psp4.12937. Epub 2023 Feb 27. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36782356 Free PMC article.