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Zuogui-Jiangtang-Yishen decoction prevents diabetic kidney disease: Intervene pyroptosis induced by trimethylamine n-oxide through the mROS-NLRP3 axis.
Yi ZY, Peng YJ, Hui BP, Liu Z, Lin QX, Zhao D, Wang Y, Liu X, Xie J, Zhang SH, Huang JH, Yu R. Yi ZY, et al. Phytomedicine. 2023 Jun;114:154775. doi: 10.1016/j.phymed.2023.154775. Epub 2023 Mar 18. Phytomedicine. 2023. PMID: 36990008
Here, the associations between TMAO-induced pyroptosis and pathogenesis of DKD were studied, and the potential mechanism of Zuogui-Jiangtang-Yishen (ZGJTYS) decoction to prevent DKD was further investigated. ...
Here, the associations between TMAO-induced pyroptosis and pathogenesis of DKD were studied, and the potential mechanism of Zuogui-Jiangtang …
Bupi Yishen Formula Versus Losartan for Non-Diabetic Stage 4 Chronic Kidney Disease: A Randomized Controlled Trial.
Mao W, Yang N, Zhang L, Li C, Wu Y, Ouyang W, Xu P, Zou C, Pei C, Shi W, Zhan J, Yang H, Chen H, Wang X, Tian Y, Yuan F, Sun W, Xiong G, Chen M, Guan J, Tang S, Zhang C, Liu Y, Deng Y, Lin Q, Lu F, Hong W, Yang A, Fang J, Rao J, Wang L, Bao K, Lin F, Xu Y, Lu Z, Su G, Zhang L, Johnson DW, Zhao D, Hou H, Fu L, Guo X, Yang L, Qin X, Wen Z, Liu X. Mao W, et al. Front Pharmacol. 2021 Jan 29;11:627185. doi: 10.3389/fphar.2020.627185. eCollection 2020. Front Pharmacol. 2021. PMID: 33708125 Free PMC article.
Chinese herbal medicine (CHM) might have benefits in patients with non-diabetic chronic kidney disease (CKD), but there is a lack of high-quality evidence, especially in CKD4. This study aimed to assess the efficacy and safety of Bupi Yishen Formula (BYF) vs. losartan in p …
Chinese herbal medicine (CHM) might have benefits in patients with non-diabetic chronic kidney disease (CKD), but there is a lack of high-qu …
Yishen Jiangzhuo Granules affect tubulointerstitial fibrosis via a mitochondrion-mediated apoptotic pathway.
Xu YF, Ruan SW, Lin JM, Zhang Z. Xu YF, et al. Chin J Integr Med. 2015 Dec;21(12):928-37. doi: 10.1007/s11655-015-2078-5. Epub 2015 May 9. Chin J Integr Med. 2015. PMID: 25956968
OBJECTIVE: To investigate the effect of Yishen Jiangzhuo Granules, YSJZG) on mitochondrial injury and regeneration and renal tubular epithelial cell apoptosis in chronic renal failure (CRF) rats and explore its mechanism from molecular pathology, gene, protein levels, and …
OBJECTIVE: To investigate the effect of Yishen Jiangzhuo Granules, YSJZG) on mitochondrial injury and regeneration and renal tubular …
Emerging Biological Functions of IL-17A: A New Target in Chronic Obstructive Pulmonary Disease?
Liu M, Wu K, Lin J, Xie Q, Liu Y, Huang Y, Zeng J, Yang Z, Wang Y, Dong S, Deng W, Yang M, Wu S, Jiang W, Li X. Liu M, et al. Front Pharmacol. 2021 Jul 2;12:695957. doi: 10.3389/fphar.2021.695957. eCollection 2021. Front Pharmacol. 2021. PMID: 34305606 Free PMC article. Review.
Moreover, four novel efficient therapies targeting IL-17A and other molecules for COPD are also concluded, such as Bufei Yishen formula (BYF), a Traditional Chinese Medicine (TCM), and curcumin, a natural polyphenol extracted from the root of Curcuma longa....
Moreover, four novel efficient therapies targeting IL-17A and other molecules for COPD are also concluded, such as Bufei Yishen formu …
Time Course of the Effects of Buxin Yishen Decoction in Promoting Heart Function and Inhibiting the Progression of Renal Fibrosis in Myocardial Infarction Caused Type 2 Cardiorenal Syndrome Rats.
Qiu Q, Cao J, Wang Y, Zhang Y, Wei Y, Hao X, Mu Y, Lin Y. Qiu Q, et al. Front Pharmacol. 2019 Oct 23;10:1267. doi: 10.3389/fphar.2019.01267. eCollection 2019. Front Pharmacol. 2019. PMID: 31708787 Free PMC article.
This study aimed to investigate the therapeutic effect of traditional Chinese medicine-Buxin Yishen decoction (BXYS) on type 2 cardiorenal syndrome (CRS) caused by myocardial infarction and explore the possible mechanism BXYS works. ...
This study aimed to investigate the therapeutic effect of traditional Chinese medicine-Buxin Yishen decoction (BXYS) on type 2 cardio …
[Yishen Tonglong Decoction inhibits the epithelial-mesenchymal transition and Ras/ERK signaling pathway in human prostate cancer DU-145 cells].
Liu DG, Li ZR, Chen QH, Zhao J, Su YF, Xiang SZ, Lin MJ. Liu DG, et al. Zhonghua Nan Ke Xue. 2021 Oct 20;27(10):909-916. Zhonghua Nan Ke Xue. 2021. PMID: 34914270 Chinese.
OBJECTIVE: To observe the effect of Yishen Tonglong Decoction (YTD) on the epithelial-mesenchymal transition (EMT) and Ras/ERK signaling pathway in human PCa DU-145 cells and explore its action mechanism. ...The mechanism of Yishen Tonglong Decoction acting on PCa m …
OBJECTIVE: To observe the effect of Yishen Tonglong Decoction (YTD) on the epithelial-mesenchymal transition (EMT) and Ras/ERK signal …
[Xiongcan Yishen Prescription up-regulates the expressions of cholesterol transport proteins, steroidogenic enzymes and SF-1 in the Leydig cells of rats with late-onset hypogonadism].
Zhou X, Li BN, Zhou HL, He QH, Zhou Q, Xiong W, Gao RS, Lin QF, Shang XJ. Zhou X, et al. Zhonghua Nan Ke Xue. 2020 Mar;26(3):258-264. Zhonghua Nan Ke Xue. 2020. PMID: 33346967 Chinese.
OBJECTIVE: To investigate the effects of Xiongcan Yishen Prescription (XYP) on the expressions of cholesterol transport proteins, steroidogenic enzymes and steroidogenic factor-1 (SF-1) in the Leydig cells of the rats with late-onset hypogonadism (LOH). ...RESULTS: The exp …
OBJECTIVE: To investigate the effects of Xiongcan Yishen Prescription (XYP) on the expressions of cholesterol transport proteins, ste …
Rationale and design of the Helping Ease Renal failure with Bupi Yishen compared with the Angiotensin II Antagonist Losartan (HERBAAL) trial: a randomized controlled trial in non-diabetes stage 4 chronic kidney disease.
Mao W, Zhang L, Zou C, Li C, Wu Y, Su G, Guo X, Wu Y, Lu F, Lin Q, Wang L, Bao K, Xu P, Zhao D, Peng Y, Liang H, Lu Z, Gao Y, Jie X, Zhang L, Wen Z, Liu X. Mao W, et al. BMC Complement Altern Med. 2015 Sep 8;15:316. doi: 10.1186/s12906-015-0830-1. BMC Complement Altern Med. 2015. PMID: 26351087 Free PMC article. Clinical Trial.
Currently, as for advanced CKD populations, medication options limited in angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB), which were partially effective. A Chinese herbal compound, Bupi Yishen formula, has showed renal protective po …
Currently, as for advanced CKD populations, medication options limited in angiotensin-converting enzyme inhibitors (ACEi) and angiotensin re …
[Impacts of yishen jiangzhuo granule on B lymphocytes and regulatory T-lymphocytes in patients with chronic renal insufficiency].
Zheng J, Lin SZ, Chen XL. Zheng J, et al. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011 Jan;31(1):37-40. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011. PMID: 21434341 Clinical Trial. Chinese.
OBJECTIVE: To explore the impacts of Yishen Jiangzhuo Granule (YJG) on peripheral blood B-cells and regulatory T-cells (Treg) in patients with chronic renal insufficiency (CRI). ...
OBJECTIVE: To explore the impacts of Yishen Jiangzhuo Granule (YJG) on peripheral blood B-cells and regulatory T-cells (Treg) in pati …
12 results