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Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia.
Koskuvi M, Lehtonen Š, Trontti K, Keuters M, Wu YC, Koivisto H, Ludwig A, Plotnikova L, Virtanen PLJ, Räsänen N, Kaipainen S, Hyötyläinen I, Dhungana H, Giniatullina R, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Lähteenvuo M, Tohka J, Giniatullin R, Rivera C, Hovatta I, Tanila H, Tiihonen J, Koistinaho J. Koskuvi M, et al. Among authors: wu yc. Glia. 2022 Apr;70(4):650-660. doi: 10.1002/glia.24131. Epub 2021 Dec 22. Glia. 2022. PMID: 34936134 Free PMC article.
Genetic contribution to microglial activation in schizophrenia.
Koskuvi M, Pörsti E, Hewitt T, Räsänen N, Wu YC, Trontti K, McQuade A, Kalyanaraman S, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Blurton-Jones M, Hovatta I, Lähteenvuo M, Rolova T, Lehtonen Š, Tiihonen J, Koistinaho J. Koskuvi M, et al. Among authors: wu yc. Mol Psychiatry. 2024 Mar 22. doi: 10.1038/s41380-024-02529-1. Online ahead of print. Mol Psychiatry. 2024. PMID: 38519640
KI Essence extract (a spleen-tonifying formula) promotes neurite outgrowth, alleviates oxidative stress and hypomyelination, and modulates microbiome in maternal immune activation offspring.
Lee GA, Zhao HW, Chang YW, Lee CJ, Yang YSH, Wu YC, Lin WL, Liu YR, Ning DS, Tseng SH. Lee GA, et al. Among authors: wu yc. Front Pharmacol. 2022 Aug 25;13:964255. doi: 10.3389/fphar.2022.964255. eCollection 2022. Front Pharmacol. 2022. PMID: 36091751 Free PMC article.
Generation of a human induced pluripotent stem cell line (UEFi003-A) carrying heterozygous A673T variant in amyloid precursor protein associated with a reduced risk of Alzheimer's disease.
Rolova T, Wu YC, Koskuvi M, Voutilainen J, Sonninen TM, Kuusisto J, Laakso M, Hämäläinen RH, Koistinaho J, Lehtonen Š. Rolova T, et al. Among authors: wu yc. Stem Cell Res. 2020 Oct;48:101968. doi: 10.1016/j.scr.2020.101968. Epub 2020 Sep 2. Stem Cell Res. 2020. PMID: 32911327 Free article.