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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1969 1
1973 1
1976 2
1980 2
1983 3
1985 7
1986 5
1987 9
1988 9
1989 15
1990 20
1991 18
1992 25
1993 21
1994 32
1995 51
1996 49
1997 61
1998 61
1999 90
2000 92
2001 112
2002 107
2003 146
2004 181
2005 198
2006 251
2007 301
2008 325
2009 372
2010 484
2011 562
2012 630
2013 744
2014 894
2015 956
2016 929
2017 1111
2018 1213
2019 1377
2020 1504
2021 1693
2022 1849
2023 1763
2024 752

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16,964 results

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The following term was not found in PubMed: Yeau-Jian
Page 1
African swine fever virus I73R is a critical virulence-related gene: A potential target for attenuation.
Liu Y, Shen Z, Xie Z, Song Y, Li Y, Liang R, Gong L, Di D, Liu J, Liu J, Chen Z, Yu W, Lv L, Zhong Q, Liao X, Tian C, Wang R, Song Q, Wang H, Peng G, Chen H. Liu Y, et al. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2210808120. doi: 10.1073/pnas.2210808120. Epub 2023 Apr 6. Proc Natl Acad Sci U S A. 2023. PMID: 37023125 Free PMC article.
Whereas some ASFV proteins have been found to play important roles in ASFV-host interaction, the functional roles of many proteins are still largely unknown. In this study, we identified I73R, an early viral gene in the replication cycle of ASFV, as a key virulence factor. …
Whereas some ASFV proteins have been found to play important roles in ASFV-host interaction, the functional roles of many proteins are still …
Functional profiling of the Saccharomyces cerevisiae genome.
Giaever G, Chu AM, Ni L, Connelly C, Riles L, Véronneau S, Dow S, Lucau-Danila A, Anderson K, André B, Arkin AP, Astromoff A, El-Bakkoury M, Bangham R, Benito R, Brachat S, Campanaro S, Curtiss M, Davis K, Deutschbauer A, Entian KD, Flaherty P, Foury F, Garfinkel DJ, Gerstein M, Gotte D, Güldener U, Hegemann JH, Hempel S, Herman Z, Jaramillo DF, Kelly DE, Kelly SL, Kötter P, LaBonte D, Lamb DC, Lan N, Liang H, Liao H, Liu L, Luo C, Lussier M, Mao R, Menard P, Ooi SL, Revuelta JL, Roberts CJ, Rose M, Ross-Macdonald P, Scherens B, Schimmack G, Shafer B, Shoemaker DD, Sookhai-Mahadeo S, Storms RK, Strathern JN, Valle G, Voet M, Volckaert G, Wang CY, Ward TR, Wilhelmy J, Winzeler EA, Yang Y, Yen G, Youngman E, Yu K, Bussey H, Boeke JD, Snyder M, Philippsen P, Davis RW, Johnston M. Giaever G, et al. Nature. 2002 Jul 25;418(6896):387-91. doi: 10.1038/nature00935. Nature. 2002. PMID: 12140549
Determining the effect of gene deletion is a fundamental approach to understanding gene function. Conventional genetic screens exhibit biases, and genes contributing to a phenotype are often missed. We systematically constructed a nearly complete collection o …
Determining the effect of gene deletion is a fundamental approach to understanding gene function. Conventional genetic screens …
Pan-genome analysis of 33 genetically diverse rice accessions reveals hidden genomic variations.
Qin P, Lu H, Du H, Wang H, Chen W, Chen Z, He Q, Ou S, Zhang H, Li X, Li X, Li Y, Liao Y, Gao Q, Tu B, Yuan H, Ma B, Wang Y, Qian Y, Fan S, Li W, Wang J, He M, Yin J, Li T, Jiang N, Chen X, Liang C, Li S. Qin P, et al. Cell. 2021 Jun 24;184(13):3542-3558.e16. doi: 10.1016/j.cell.2021.04.046. Epub 2021 May 28. Cell. 2021. PMID: 34051138 Free article.
Structural variations (SVs) and gene copy number variations (gCNVs) have contributed to crop evolution, domestication, and improvement. ...Specifically, we discovered 171,072 SVs and 25,549 gCNVs and used an Oryza glaberrima assembly to infer the derived states of SVs in t …
Structural variations (SVs) and gene copy number variations (gCNVs) have contributed to crop evolution, domestication, and improvemen …
A mechanism for oxidative damage repair at gene regulatory elements.
Ray S, Abugable AA, Parker J, Liversidge K, Palminha NM, Liao C, Acosta-Martin AE, Souza CDS, Jurga M, Sudbery I, El-Khamisy SF. Ray S, et al. Nature. 2022 Sep;609(7929):1038-1047. doi: 10.1038/s41586-022-05217-8. Epub 2022 Sep 28. Nature. 2022. PMID: 36171374 Free article.
NuMA promotes transcription by limiting the polyADP-ribosylation of RNA polymerase II, increasing its availability and release from pausing at promoters. Metabolic labelling of nascent RNA identifies genes that depend on NuMA for transcription including immediate-early res …
NuMA promotes transcription by limiting the polyADP-ribosylation of RNA polymerase II, increasing its availability and release from pausing …
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis.
Winzeler EA, Shoemaker DD, Astromoff A, Liang H, Anderson K, Andre B, Bangham R, Benito R, Boeke JD, Bussey H, Chu AM, Connelly C, Davis K, Dietrich F, Dow SW, El Bakkoury M, Foury F, Friend SH, Gentalen E, Giaever G, Hegemann JH, Jones T, Laub M, Liao H, Liebundguth N, Lockhart DJ, Lucau-Danila A, Lussier M, M'Rabet N, Menard P, Mittmann M, Pai C, Rebischung C, Revuelta JL, Riles L, Roberts CJ, Ross-MacDonald P, Scherens B, Snyder M, Sookhai-Mahadeo S, Storms RK, Véronneau S, Voet M, Volckaert G, Ward TR, Wysocki R, Yen GS, Yu K, Zimmermann K, Philippsen P, Johnston M, Davis RW. Winzeler EA, et al. Science. 1999 Aug 6;285(5429):901-6. doi: 10.1126/science.285.5429.901. Science. 1999. PMID: 10436161
c-Myc in breast cancer.
Liao DJ, Dickson RB. Liao DJ, et al. Endocr Relat Cancer. 2000 Sep;7(3):143-64. doi: 10.1677/erc.0.0070143. Endocr Relat Cancer. 2000. PMID: 11021963 Review.
Ever since Bishop and his co-workers discovered the c-myc gene in the late 1970s (Bishop 1982), voluminous literature has documented its central role in proliferation and malignant transformation of human and animal cells (Amati et al. 1998, Bouchard et al. 1998, Dang et a …
Ever since Bishop and his co-workers discovered the c-myc gene in the late 1970s (Bishop 1982), voluminous literature has documented …
Pet cats may shape the antibiotic resistome of their owner's gut and living environment.
Yang Y, Hu X, Cai S, Hu N, Yuan Y, Wu Y, Wang Y, Mi J, Liao X. Yang Y, et al. Microbiome. 2023 Oct 23;11(1):235. doi: 10.1186/s40168-023-01679-8. Microbiome. 2023. PMID: 37872584 Free PMC article.

RESULTS: Results showed that the abundance of ARGs in the cat gut was significantly higher than that in the human gut (P < 0.0001), with aminoglycoside and tetracycline resistance genes being the dominant ARGs in the cat gut. There was no significant difference in the a

…

RESULTS: Results showed that the abundance of ARGs in the cat gut was significantly higher than that in the human gut (P < 0.0001), with

…
A revolutionary tool: CRISPR technology plays an important role in construction of intelligentized gene circuits.
Zhou Q, Zhan H, Liao X, Fang L, Liu Y, Xie H, Yang K, Gao Q, Ding M, Cai Z, Huang W, Liu Y. Zhou Q, et al. Cell Prolif. 2019 Mar;52(2):e12552. doi: 10.1111/cpr.12552. Epub 2018 Dec 5. Cell Prolif. 2019. PMID: 30520167 Free PMC article. Review.
An ultimate challenge in the construction of gene circuits is the lack of effective, programmable, secure and sequence-specific gene editing tools. ...The traditional single-targeted therapy cannot effectively distinguish tumour cells from normal cells, and gene …
An ultimate challenge in the construction of gene circuits is the lack of effective, programmable, secure and sequence-specific ge …
CRISPR system in filamentous fungi: Current achievements and future directions.
Deng H, Gao R, Liao X, Cai Y. Deng H, et al. Gene. 2017 Sep 5;627:212-221. doi: 10.1016/j.gene.2017.06.019. Epub 2017 Jun 16. Gene. 2017. PMID: 28625564 Review.
We also highlight several methods that improve the nuclease specificity and efficiency, and discuss current and potential applications of CRISPR/Cas9 system in filamentous fungi for pathogenesis decoding, confirmation of the gene and pathway, bioenergy process, drug discov …
We also highlight several methods that improve the nuclease specificity and efficiency, and discuss current and potential applications of CR …
The other side of the coin: the tumor-suppressive aspect of oncogenes and the oncogenic aspect of tumor-suppressive genes, such as those along the CCND-CDK4/6-RB axis.
Lou X, Zhang J, Liu S, Xu N, Liao DJ. Lou X, et al. Cell Cycle. 2014;13(11):1677-93. doi: 10.4161/cc.29082. Epub 2014 May 5. Cell Cycle. 2014. PMID: 24799665 Free PMC article. Review.
Although cancer-regulatory genes are dichotomized to oncogenes and tumor-suppressor gene s, in reality they can be oncogenic in one situation but tumor-suppressive in another. ...Redefining "gene" by considering each mRNA, regulatory RNA, protein isoform, and …
Although cancer-regulatory genes are dichotomized to oncogenes and tumor-suppressor gene s, in reality they can be oncogenic i …
16,964 results
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