Desulfonylation of tosyl amides through catalytic photoredox cleavage of N-S bond under visible-light irradiation

Jun Xuan; Bin-Jie Li; Zhu-Jia Feng; Guo-Dong Sun; Huan-Huan Ma; Zhi-Wei Yuan; Jia-Rong Chen; Liang-Qiu Lu; Wen-Jing Xiao

doi:10.1002/asia.201300224

Desulfonylation of tosyl amides through catalytic photoredox cleavage of N-S bond under visible-light irradiation

Chem Asian J. 2013 Jun;8(6):1090-4. doi: 10.1002/asia.201300224. Epub 2013 Apr 3.

Authors

Jun Xuan¹, Bin-Jie Li, Zhu-Jia Feng, Guo-Dong Sun, Huan-Huan Ma, Zhi-Wei Yuan, Jia-Rong Chen, Liang-Qiu Lu, Wen-Jing Xiao

Affiliation

¹ Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, PR China.

PMID: 23554359
DOI: 10.1002/asia.201300224

Abstract

All lit up: A novel and efficient desulfonylation method of tosyl amides has been developed by means of visible-light-promoted reductive cleavage of N-S bonds. This method has a broad substrate scope, good functional group tolerance, and excellent yields.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amides / chemistry*
Amides / radiation effects
Catalysis
Light*
Molecular Structure
Oxidation-Reduction
Photochemical Processes*
Photochemistry
Tosyl Compounds / chemistry*
Tosyl Compounds / radiation effects

Substances

Amides
Tosyl Compounds