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606 results

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Page 1
Showing results for finger ye
Search for Xinger Ye instead (1 results)
Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells.
Xiong J, He J, Zhu J, Pan J, Liao W, Ye H, Wang H, Song Y, Du Y, Cui B, Xue M, Zheng W, Kong X, Jiang K, Ding K, Lai L, Wang Q. Xiong J, et al. Mol Cell. 2022 May 5;82(9):1660-1677.e10. doi: 10.1016/j.molcel.2022.02.033. Epub 2022 Mar 22. Mol Cell. 2022. PMID: 35320754 Free article.
Interestingly, we identified two lactylation modification sites in the zinc-finger domain of METTL3, which was essential for METTL3 to capture target RNA. ...
Interestingly, we identified two lactylation modification sites in the zinc-finger domain of METTL3, which was essential for METTL3 t …
The transcription factor ZEB2 drives the formation of age-associated B cells.
Dai D, Gu S, Han X, Ding H, Jiang Y, Zhang X, Yao C, Hong S, Zhang J, Shen Y, Hou G, Qu B, Zhou H, Qin Y, He Y, Ma J, Yin Z, Ye Z, Qian J, Jiang Q, Wu L, Guo Q, Chen S, Huang C, Kottyan LC, Weirauch MT, Vinuesa CG, Shen N. Dai D, et al. Science. 2024 Jan 26;383(6681):413-421. doi: 10.1126/science.adf8531. Epub 2024 Jan 25. Science. 2024. PMID: 38271512
In this study, we screened for transcription factors driving ABC formation and found that zinc finger E-box binding homeobox 2 (ZEB2) is required for human and mouse ABC differentiation in vitro. ...
In this study, we screened for transcription factors driving ABC formation and found that zinc finger E-box binding homeobox 2 (ZEB2) …
Cellular heterogeneity and transcriptomic profiles during intrahepatic cholangiocarcinoma initiation and progression.
Wang T, Xu C, Zhang Z, Wu H, Li X, Zhang Y, Deng N, Dang N, Tang G, Yang X, Shi B, Li Z, Li L, Ye K. Wang T, et al. Hepatology. 2022 Nov;76(5):1302-1317. doi: 10.1002/hep.32483. Epub 2022 Apr 24. Hepatology. 2022. PMID: 35340039 Free PMC article.
By integrating weighted correlation network analysis and protein-protein interaction through least absolute shrinkage and selection operator regression, we identified zinc finger, MIZ-type containing 1 (Zmiz1) and Y box protein 1 (Ybx1) as core transcription factors requir …
By integrating weighted correlation network analysis and protein-protein interaction through least absolute shrinkage and selection operator …
Targeting UBE2T Potentiates Gemcitabine Efficacy in Pancreatic Cancer by Regulating Pyrimidine Metabolism and Replication Stress.
Jiang X, Ma Y, Wang T, Zhou H, Wang K, Shi W, Qin L, Guan J, Li L, Long B, Wang J, Guan X, Ye H, Yang J, Yu Z, Jiao Z. Jiang X, et al. Gastroenterology. 2023 Jun;164(7):1232-1247. doi: 10.1053/j.gastro.2023.02.025. Epub 2023 Feb 25. Gastroenterology. 2023. PMID: 36842710
RESULTS: Spontaneous PC mice with Ube2t deletion had a marked survival advantage after gemcitabine treatment, and UBE2T levels were positively correlated with gemcitabine resistance in clinical patients. Mechanistically, UBE2T catalyzes ring finger protein 1 (RING1)-mediat …
RESULTS: Spontaneous PC mice with Ube2t deletion had a marked survival advantage after gemcitabine treatment, and UBE2T levels were positive …
Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer.
Zhang X, Luo F, Luo S, Li L, Ren X, Lin J, Liang Y, Ma C, Ding L, Zhang D, Ye T, Lin Y, Jin B, Gao S, Ye Q. Zhang X, et al. Adv Sci (Weinh). 2022 Sep;9(27):e2200705. doi: 10.1002/advs.202200705. Epub 2022 Jul 27. Adv Sci (Weinh). 2022. PMID: 35896951 Free PMC article.
Aerobic glycolysis (Warburg effect), a hallmark of cancer, plays a critical role in cancer cell growth and metastasis; however, direct inhibition of the Warburg effect remains largely unknown. Herein, the transcription factor OVO-like zinc finger 2 (OVOL2) is demonstrated …
Aerobic glycolysis (Warburg effect), a hallmark of cancer, plays a critical role in cancer cell growth and metastasis; however, direct inhib …
N protein of PEDV plays chess game with host proteins by selective autophagy.
Zhai X, Kong N, Zhang Y, Song Y, Qin W, Yang X, Ye C, Ye M, Tong W, Liu C, Zheng H, Yu H, Zhang W, Yang X, Zhang G, Tong G, Shan T. Zhai X, et al. Autophagy. 2023 Aug;19(8):2338-2352. doi: 10.1080/15548627.2023.2181615. Epub 2023 Mar 2. Autophagy. 2023. PMID: 36861818 Free PMC article.
These results reveal the dual function of selective autophagy in PEDV N and host proteins, which could promote the ubiquitination of viral particles and host antiviral proteins and degradation both of the proteins to regulate the relationship between virus infection and host inna …
These results reveal the dual function of selective autophagy in PEDV N and host proteins, which could promote the ubiquitination of viral p …
Zinc finger proteins and regulation of the hallmarks of cancer.
Ye Q, Liu J, Xie K. Ye Q, et al. Histol Histopathol. 2019 Oct;34(10):1097-1109. doi: 10.14670/HH-18-121. Epub 2019 May 2. Histol Histopathol. 2019. PMID: 31045237 Review.
Zinc finger proteins (ZFPs) form one of the largest families of transcription factors in human genetics, via their conserved zinc finger motifs. ...
Zinc finger proteins (ZFPs) form one of the largest families of transcription factors in human genetics, via their conserved zinc …
The Phytophthora sojae nuclear effector PsAvh110 targets a host transcriptional complex to modulate plant immunity.
Qiu X, Kong L, Chen H, Lin Y, Tu S, Wang L, Chen Z, Zeng M, Xiao J, Yuan P, Qiu M, Wang Y, Ye W, Duan K, Dong S, Wang Y. Qiu X, et al. Plant Cell. 2023 Jan 2;35(1):574-597. doi: 10.1093/plcell/koac300. Plant Cell. 2023. PMID: 36222564 Free PMC article.
Soybean like-heterochromatin protein 1-2 (GmLHP1-2) and plant homeodomain finger protein 6 (GmPHD6) form a transcriptional complex with transcriptional activity that positively regulates plant immunity against Phytophthora infection. ...
Soybean like-heterochromatin protein 1-2 (GmLHP1-2) and plant homeodomain finger protein 6 (GmPHD6) form a transcriptional complex wi …
RNF213 loss-of-function promotes pathological angiogenesis in moyamoya disease via the Hippo pathway.
Ye F, Niu X, Liang F, Dai Y, Liang J, Li J, Wu X, Zheng H, Qi T, Sheng W. Ye F, et al. Brain. 2023 Nov 2;146(11):4674-4689. doi: 10.1093/brain/awad225. Brain. 2023. PMID: 37399508 Free PMC article.
Moyamoya disease is an uncommon cerebrovascular disorder characterized by steno-occlusive changes in the circle of Willis and abnormal vascular network development. Ring finger protein 213 (RNF213) has been identified as an important susceptibility gene for Asian patients, …
Moyamoya disease is an uncommon cerebrovascular disorder characterized by steno-occlusive changes in the circle of Willis and abnormal vascu …
606 results