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Year Number of Results
2008 3
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2010 1
2011 2
2012 2
2013 3
2014 1
2015 2
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2017 6
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2020 11
2021 9
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2023 6
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61 results

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Page 1
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs.
Johannes JW, Balazs A, Barratt D, Bista M, Chuba MD, Cosulich S, Critchlow SE, Degorce SL, Di Fruscia P, Edmondson SD, Embrey K, Fawell S, Ghosh A, Gill SJ, Gunnarsson A, Hande SM, Heightman TD, Hemsley P, Illuzzi G, Lane J, Larner C, Leo E, Liu L, Madin A, Martin S, McWilliams L, O'Connor MJ, Orme JP, Pachl F, Packer MJ, Pei X, Pike A, Schimpl M, She H, Staniszewska AD, Talbot V, Underwood E, Varnes JG, Xue L, Yao T, Zhang K, Zhang AX, Zheng X. Johannes JW, et al. Among authors: zheng x. J Med Chem. 2021 Oct 14;64(19):14498-14512. doi: 10.1021/acs.jmedchem.1c01012. Epub 2021 Sep 27. J Med Chem. 2021. PMID: 34570508
Diagnostic significance of microRNAs in sepsis.
Zheng X, Zhang Y, Lin S, Li Y, Hua Y, Zhou K. Zheng X, et al. PLoS One. 2023 Feb 22;18(2):e0279726. doi: 10.1371/journal.pone.0279726. eCollection 2023. PLoS One. 2023. PMID: 36812225 Free PMC article.
Attenuation of Cardiomyocyte Hypertrophy via Depletion Myh7 using CASAAV.
Yue P, Xia S, Wu G, Liu L, Zhou K, Liao H, Li J, Zheng X, Guo Y, Hua Y, Zhang D, Li Y. Yue P, et al. Among authors: zheng x. Cardiovasc Toxicol. 2021 Mar;21(3):255-264. doi: 10.1007/s12012-020-09617-y. Epub 2020 Oct 23. Cardiovasc Toxicol. 2021. PMID: 33098074
Optimization of a series of novel, potent and selective Macrocyclic SYK inhibitors.
Grimster NP, Gingipalli L, Balazs A, Barlaam B, Boiko S, Boyd S, Dry H, Goldberg FW, Ikeda T, Johnson T, Kawatkar S, Kemmitt P, Lamont S, Lorthioir O, Mfuh A, Patel J, Pike A, Read J, Romero R, Sarkar U, Sha L, Simpson I, Song K, Su Q, Wang H, Watson D, Wu A, Zehnder TE, Zheng X, Li S, Dong Z, Yang D, Song Y, Wang P, Liu X, Dowling JE, Edmondson SD. Grimster NP, et al. Among authors: zheng x. Bioorg Med Chem Lett. 2023 Jul 15;91:129352. doi: 10.1016/j.bmcl.2023.129352. Epub 2023 Jun 2. Bioorg Med Chem Lett. 2023. PMID: 37270074
61 results