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Sculponeatin A promotes the ETS1-SYVN1 interaction to induce SLC7A11/xCT-dependent ferroptosis in breast cancer.
Phytomedicine. 2023 Aug;117:154921. doi: 10.1016/j.phymed.2023.154921. Epub 2023 Jun 8.
Phytomedicine. 2023.
PMID: 37327642
Acetylation of MOB1 mediates polyphyllin II-reduced lysosome biogenesis in breast cancer by promoting the cytoplasmic retention of the YAP/TFEB coactivator complex.
Ren Y, Wu H, Tan M, Chen J, Duan Z, Zhu B, Ruan X, Yu Q, Li S, Liu X, Liu Y, Si Y.
Ren Y, et al.
Phytomedicine. 2024 Jan;122:155152. doi: 10.1016/j.phymed.2023.155152. Epub 2023 Oct 15.
Phytomedicine. 2024.
PMID: 37922793
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Cucurbitacin B inhibits gastric cancer progression by suppressing STAT3 activity.
Xu J, Chen Y, Yang R, Zhou T, Ke W, Si Y, Yang S, Zhang T, Liu X, Zhang L, Xiang K, Guo Y, Liu Y.
Xu J, et al.
Arch Biochem Biophys. 2020 May 15;684:108314. doi: 10.1016/j.abb.2020.108314. Epub 2020 Feb 20.
Arch Biochem Biophys. 2020.
PMID: 32088220
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Paris saponin VII, a Hippo pathway activator, induces autophagy and exhibits therapeutic potential against human breast cancer cells.
Xiang YC, Peng P, Liu XW, Jin X, Shen J, Zhang T, Zhang L, Wan F, Ren YL, Yu QQ, Zhao HZ, Si Y, Liu Y.
Xiang YC, et al.
Acta Pharmacol Sin. 2022 Jun;43(6):1568-1580. doi: 10.1038/s41401-021-00755-9. Epub 2021 Sep 14.
Acta Pharmacol Sin. 2022.
PMID: 34522004
Free PMC article.
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Polyphyllin I activates AMPK to suppress the growth of non-small-cell lung cancer via induction of autophagy.
Wu Y, Si Y, Xiang Y, Zhou T, Liu X, Wu M, Li W, Zhang T, Xiang K, Zhang L, Zhao H, Liu Y.
Wu Y, et al.
Arch Biochem Biophys. 2020 Jul 15;687:108285. doi: 10.1016/j.abb.2020.108285. Epub 2020 Feb 16.
Arch Biochem Biophys. 2020.
PMID: 32074500
Free article.
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Paris saponin VII, a direct activator of AMPK, induces autophagy and exhibits therapeutic potential in non-small-cell lung cancer.
Xiang YC, Shen J, Si Y, Liu XW, Zhang L, Wen J, Zhang T, Yu QQ, Lu JF, Xiang K, Liu Y.
Xiang YC, et al.
Chin J Nat Med. 2021 Mar;19(3):195-204. doi: 10.1016/S1875-5364(21)60021-3.
Chin J Nat Med. 2021.
PMID: 33781453
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Cucurbitacin B Induces the Lysosomal Degradation of EGFR and Suppresses the CIP2A/PP2A/Akt Signaling Axis in Gefitinib-Resistant Non-Small Cell Lung Cancer.
Liu P, Xiang Y, Liu X, Zhang T, Yang R, Chen S, Xu L, Yu Q, Zhao H, Zhang L, Liu Y, Si Y.
Liu P, et al.
Molecules. 2019 Feb 12;24(3):647. doi: 10.3390/molecules24030647.
Molecules. 2019.
PMID: 30759826
Free PMC article.
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