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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 1
1951 3
1952 2
1953 5
1954 5
1955 4
1956 4
1957 4
1958 6
1959 5
1961 1
1963 99
1964 174
1965 69
1966 1
1967 3
1968 7
1969 10
1970 5
1971 2
1972 7
1973 4
1974 7
1975 4
1976 10
1977 9
1978 8
1979 3
1980 2
1981 7
1982 1
1983 1
1984 8
1985 4
1986 3
1987 7
1988 7
1989 8
1990 7
1991 5
1992 13
1993 13
1994 18
1995 10
1996 19
1997 22
1998 28
1999 46
2000 43
2001 41
2002 70
2003 51
2004 63
2005 84
2006 68
2007 116
2008 122
2009 102
2010 123
2011 159
2012 149
2013 148
2014 226
2015 260
2016 241
2017 260
2018 273
2019 270
2020 291
2021 323
2022 325
2023 352
2024 150

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4,523 results

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The following terms were not found in PubMed: Worapree, Maneesoonthorn
Page 1
Lecanemab in patients with early Alzheimer's disease: detailed results on biomarker, cognitive, and clinical effects from the randomized and open-label extension of the phase 2 proof-of-concept study.
McDade E, Cummings JL, Dhadda S, Swanson CJ, Reyderman L, Kanekiyo M, Koyama A, Irizarry M, Kramer LD, Bateman RJ. McDade E, et al. Alzheimers Res Ther. 2022 Dec 21;14(1):191. doi: 10.1186/s13195-022-01124-2. Alzheimers Res Ther. 2022. PMID: 36544184 Free PMC article. Clinical Trial.
The objective of this analysis is to report results from study 201 blinded period (core), the open-label extension (OLE), and gap period (between core and OLE) supporting the effectiveness of lecanemab. ...In the OLE, lecanemab 10 mg/kg biweekly treatment pro …
The objective of this analysis is to report results from study 201 blinded period (core), the open-label extension (OLE), and gap per …
Survival analyses from the CENTAUR trial in amyotrophic lateral sclerosis: Evaluating the impact of treatment crossover on outcomes.
Paganoni S, Watkins C, Cawson M, Hendrix S, Dickson SP, Knowlton N, Timmons J, Manuel M, Cudkowicz M. Paganoni S, et al. Muscle Nerve. 2022 Aug;66(2):136-141. doi: 10.1002/mus.27569. Epub 2022 May 31. Muscle Nerve. 2022. PMID: 35508892 Free PMC article. Clinical Trial.
Analyses of subgroups based on randomized treatment and OLE phase participation were also performed. RESULTS: Hazard ratios (95% confidence intervals) of death for PB and TURSO versus participants initially on placebo were 0.57 (0.35-0.92) on ITT analysis and 0.39 (0.17-0. …
Analyses of subgroups based on randomized treatment and OLE phase participation were also performed. RESULTS: Hazard ratios (95% conf …
Injection Site Reactions with Long-Term Pegcetacoplan Use in Patients with Paroxysmal Nocturnal Hemoglobinuria: A Brief Report.
Sharma V, Koprivnikar J, Drago K, Savage J, Bachelor A. Sharma V, et al. Adv Ther. 2023 Nov;40(11):5115-5129. doi: 10.1007/s12325-023-02653-4. Epub 2023 Sep 14. Adv Ther. 2023. PMID: 37707673 Free PMC article.
Most patients with ISRs in the 307 OLE had events with a maximum severity of mild (7/9 patients; 77.8%). ...TRIAL REGISTRATION: ClinicalTrials.gov identifiers: NCT03500549 (PEGASUS) and NCT03531255 (307 OLE)....
Most patients with ISRs in the 307 OLE had events with a maximum severity of mild (7/9 patients; 77.8%). ...TRIAL REGISTRATION: Clini …
Change to Mixed-Lipid Emulsion From Soybean Oil-Based Lipid Emulsion in Pediatric Patients.
Haines KL, Ohnuma T, Hornik CD, Grisel B, Leraas H, Trujillo CN, Krishnamoorthy V, Raghunathan K, Wischmeyer PE. Haines KL, et al. JAMA Netw Open. 2023 Sep 5;6(9):e2332389. doi: 10.1001/jamanetworkopen.2023.32389. JAMA Netw Open. 2023. PMID: 37669048 Free PMC article.
EXPOSURE: In 2017, Duke University Health System fully converted to a soybean oil/MCT/olive/fish oil lipid (4-OLE) from pure soybean oil-based LE in pediatric patients. Pediatric patients before the change (Intralipid [IL] group) were compared with patients after (4-OLE …
EXPOSURE: In 2017, Duke University Health System fully converted to a soybean oil/MCT/olive/fish oil lipid (4-OLE) from pure soybean …
Durable biochemical response and safety with oral octreotide capsules in acromegaly.
Samson SL, Nachtigall LB, Fleseriu M, Jensterle M, Manning PJ, Elenkova A, Molitch ME, Ludlam WH, Patou G, Haviv A, Biermasz NR, Giustina A, Strasburger CJ, Kennedy L, Melmed S. Samson SL, et al. Eur J Endocrinol. 2022 Oct 26;187(6):733-741. doi: 10.1530/EJE-22-0220. Print 2022 Dec 1. Eur J Endocrinol. 2022. PMID: 36173649 Free PMC article. Clinical Trial.
DESIGN: The study design is an OLE of a double-blind placebo-controlled (DPC) trial. METHODS: Patients completing the 36-week DPC period on the study drug (OOC or placebo) or meeting predefined withdrawal criteria were eligible for OLE enrollment at 60 mg/day OOC do …
DESIGN: The study design is an OLE of a double-blind placebo-controlled (DPC) trial. METHODS: Patients completing the 36-week DPC per …
Control of membrane fluidity: the OLE pathway in focus.
Ballweg S, Ernst R. Ballweg S, et al. Biol Chem. 2017 Feb 1;398(2):215-228. doi: 10.1515/hsz-2016-0277. Biol Chem. 2017. PMID: 27787227 Free article. Review.
Saccharomyces cerevisiae is an ideal model organism to study the regulation of the lipid acyl chain composition via the OLE pathway. The OLE pathway comprises all steps involved in the regulated mobilization of the transcription factors Mga2 and Spt23 from the endop …
Saccharomyces cerevisiae is an ideal model organism to study the regulation of the lipid acyl chain composition via the OLE pathway. …
Evidence that OLE RNA is a component of a major stress-responsive ribonucleoprotein particle in extremophilic bacteria.
Breaker RR, Harris KA, Lyon SE, Wencker FDR, Fernando CM. Breaker RR, et al. Mol Microbiol. 2023 Sep;120(3):324-340. doi: 10.1111/mmi.15129. Epub 2023 Jul 20. Mol Microbiol. 2023. PMID: 37469248 Review.
OLE RNA is a ~600-nucleotide noncoding RNA present in many Gram-positive bacteria that thrive mostly in extreme environments, including elevated temperature, salt, and pH conditions. ...Herein we hypothesize that the OLE RNP complex is functionally equivalent to the …
OLE RNA is a ~600-nucleotide noncoding RNA present in many Gram-positive bacteria that thrive mostly in extreme environments, includi …
Adult occipital lobe epilepsy: 12-years on.
Angus-Leppan H, Clay TA. Angus-Leppan H, et al. J Neurol. 2021 Oct;268(10):3926-3934. doi: 10.1007/s00415-021-10557-y. Epub 2021 Apr 26. J Neurol. 2021. PMID: 33900448
METHODS: 24 adult OLE patients identified over 12 months from 1548 patients in a neurologist's service were followed over 12 years. ...CONCLUSION: Adult OLE accounted for 7.7% of focal epilepsies in this cohort, misdiagnosed or misclassified in 40%. ...
METHODS: 24 adult OLE patients identified over 12 months from 1548 patients in a neurologist's service were followed over 12 years. . …
Treatment with the Olive Secoiridoid Oleacein Protects against the Intestinal Alterations Associated with EAE.
Gutiérrez-Miranda B, Gallardo I, Melliou E, Cabero I, Álvarez Y, Hernández M, Magiatis P, Hernández M, Nieto ML. Gutiérrez-Miranda B, et al. Int J Mol Sci. 2023 Mar 4;24(5):4977. doi: 10.3390/ijms24054977. Int J Mol Sci. 2023. PMID: 36902407 Free PMC article.
Previously, we showed OLE effectiveness preventing motor defects and inflammatory damage of CNS tissues on EAE mice. ...This study proves that the protective effect of OLE in EAE also involves normalizing the gut alterations associated to the disease....
Previously, we showed OLE effectiveness preventing motor defects and inflammatory damage of CNS tissues on EAE mice. ...This study pr …
4,523 results