BRD4 inhibitor inhibits colorectal cancer growth and metastasis.
Hu Y, Zhou J, Ye F, Xiong H, Peng L, Zheng Z, Xu F, Cui M, Wei C, Wang X, Wang Z, Zhu H, Lee P, Zhou M, Jiang B, Zhang DY.
Hu Y, et al.
Int J Mol Sci. 2015 Jan 16;16(1):1928-48. doi: 10.3390/ijms16011928.
Int J Mol Sci. 2015.
PMID: 25603177
Free PMC article.
In this paper, we identify that BRD4 has an important role in colorectal cancer; and that its inhibition substantially wipes out tumor cells. Treatment with inhibitor MS417 potently affects cancer cells, although such effects were not always outright necrosis or apoptosis. …
In this paper, we identify that BRD4 has an important role in colorectal cancer; and that its inhibition substantially wipes out tumo …