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Piperlongumine inhibits lung tumor growth via inhibition of nuclear factor kappa B signaling pathway.
Zheng J, Son DJ, Gu SM, Woo JR, Ham YW, Lee HP, Kim WJ, Jung JK, Hong JT. Zheng J, et al. Sci Rep. 2016 May 20;6:26357. doi: 10.1038/srep26357. Sci Rep. 2016. PMID: 27198178 Free PMC article.
Docking model and pull down assay showed that PL directly binds to the DNA binding site of nuclear factor-kappaB (NF-kappaB) p50 subunit, and surface plasmon resonance (SPR) analysis showed that PL binds to p50 concentration-dependently. ...
Docking model and pull down assay showed that PL directly binds to the DNA binding site of nuclear factor-kappaB (NF-kappaB) p50 subu …
MMPP Attenuates Non-Small Cell Lung Cancer Growth by Inhibiting the STAT3 DNA-Binding Activity via Direct Binding to the STAT3 DNA-Binding Domain.
Son DJ, Zheng J, Jung YY, Hwang CJ, Lee HP, Woo JR, Baek SY, Ham YW, Kang MW, Shong M, Kweon GR, Song MJ, Jung JK, Han SB, Kim BY, Yoon DY, Choi BY, Hong JT. Son DJ, et al. Theranostics. 2017 Oct 16;7(18):4632-4642. doi: 10.7150/thno.18630. eCollection 2017. Theranostics. 2017. PMID: 29158850 Free PMC article.