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Connexin45 (GJC1) loss-of-function mutation contributes to familial atrial fibrillation and conduction disease.
Heart Rhythm. 2021 May;18(5):684-693. doi: 10.1016/j.hrthm.2020.12.033. Epub 2021 Jan 9.
Heart Rhythm. 2021.
PMID: 33429106
Discovery of GJC1 (Cx45) as a New Gene Underlying Congenital Heart Disease and Arrhythmias.
Li YJ, Wang J, Ye WG, Liu XY, Li L, Qiu XB, Chen H, Xu YJ, Yang YQ, Bai D, Huang RT.
Li YJ, et al. Among authors: ye wg.
Biology (Basel). 2023 Feb 21;12(3):346. doi: 10.3390/biology12030346.
Biology (Basel). 2023.
PMID: 36979038
Free PMC article.
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Atrial fibrillation-linked germline GJA5/connexin40 mutants showed an increased hemichannel function.
Sun Y, Hills MD, Ye WG, Tong X, Bai D.
Sun Y, et al. Among authors: ye wg.
PLoS One. 2014 Apr 14;9(4):e95125. doi: 10.1371/journal.pone.0095125. eCollection 2014.
PLoS One. 2014.
PMID: 24733048
Free PMC article.
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Engineered Cx40 variants increased docking and function of heterotypic Cx40/Cx43 gap junction channels.
Jassim A, Aoyama H, Ye WG, Chen H, Bai D.
Jassim A, et al. Among authors: ye wg.
J Mol Cell Cardiol. 2016 Jan;90:11-20. doi: 10.1016/j.yjmcc.2015.11.026. Epub 2015 Dec 2.
J Mol Cell Cardiol. 2016.
PMID: 26625713
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Junctional delay, frequency, and direction-dependent uncoupling of human heterotypic Cx45/Cx43 gap junction channels.
Ye WG, Yue B, Aoyama H, Kim NK, Cameron JA, Chen H, Bai D.
Ye WG, et al.
J Mol Cell Cardiol. 2017 Oct;111:17-26. doi: 10.1016/j.yjmcc.2017.07.117. Epub 2017 Jul 29.
J Mol Cell Cardiol. 2017.
PMID: 28760564
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