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The EDC4-XRN1 interaction controls P-body dynamics to link mRNA decapping with decay.
EMBO J. 2023 Nov 2;42(21):e113933. doi: 10.15252/embj.2023113933. Epub 2023 Aug 25.
EMBO J. 2023.
PMID: 37621215
Free PMC article.
P-bodies directly regulate MARF1-mediated mRNA decay in human cells.
Brothers WR, Fakim H, Kajjo S, Fabian MR.
Brothers WR, et al.
Nucleic Acids Res. 2022 Jul 22;50(13):7623-7636. doi: 10.1093/nar/gkac557.
Nucleic Acids Res. 2022.
PMID: 35801873
Free PMC article.
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PABP prevents the untimely decay of select mRNA populations in human cells.
Kajjo S, Sharma S, Chen S, Brothers WR, Cott M, Hasaj B, Jovanovic P, Larsson O, Fabian MR.
Kajjo S, et al. Among authors: brothers wr.
EMBO J. 2022 Mar 15;41(6):e108650. doi: 10.15252/embj.2021108650. Epub 2022 Feb 14.
EMBO J. 2022.
PMID: 35156721
Free PMC article.
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A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay.
Brothers WR, Hebert S, Kleinman CL, Fabian MR.
Brothers WR, et al.
Elife. 2020 Jun 8;9:e54995. doi: 10.7554/eLife.54995.
Elife. 2020.
PMID: 32510323
Free PMC article.
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Multi-Omic Analysis of CIC's Functional Networks Reveals Novel Interaction Partners and a Potential Role in Mitotic Fidelity.
Takemon Y, LeBlanc VG, Song J, Chan SY, Lee SD, Trinh DL, Ahmad ST, Brothers WR, Corbett RD, Gagliardi A, Moradian A, Cairncross JG, Yip S, Aparicio SAJR, Chan JA, Hughes CS, Morin GB, Gorski SM, Chittaranjan S, Marra MA.
Takemon Y, et al. Among authors: brothers wr.
Cancers (Basel). 2023 May 17;15(10):2805. doi: 10.3390/cancers15102805.
Cancers (Basel). 2023.
PMID: 37345142
Free PMC article.
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