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Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair.
Audu CO, Melvin WJ, Joshi AD, Wolf SJ, Moon JY, Davis FM, Barrett EC, Mangum KD, Deng H, Xing X, Wasikowski R, Tsoi LC, Sharma SB, Bauer TM, Shadiow J, Corriere MA, Obi AT, Kunkel SL, Levi B, Moore BB, Gudjonsson JE, Smith AM, Gallagher KA. Audu CO, et al. Among authors: melvin wj. Cell Mol Immunol. 2022 Nov;19(11):1251-1262. doi: 10.1038/s41423-022-00919-5. Epub 2022 Sep 20. Cell Mol Immunol. 2022. PMID: 36127466 Free PMC article.
Macrophage-mediated inflammation in diabetic wound repair.
Wolf SJ, Melvin WJ, Gallagher K. Wolf SJ, et al. Among authors: melvin wj. Semin Cell Dev Biol. 2021 Nov;119:111-118. doi: 10.1016/j.semcdb.2021.06.013. Epub 2021 Jun 26. Semin Cell Dev Biol. 2021. PMID: 34183242 Free PMC article. Review.
Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2.
Melvin WJ, Audu CO, Davis FM, Sharma SB, Joshi A, DenDekker A, Wolf S, Barrett E, Mangum K, Zhou X, Bame M, Ruan A, Obi A, Kunkel SL, Moore BB, Gallagher KA. Melvin WJ, et al. Proc Natl Acad Sci U S A. 2021 Sep 21;118(38):e2101071118. doi: 10.1073/pnas.2101071118. Proc Natl Acad Sci U S A. 2021. PMID: 34479991 Free PMC article.
IFN-κ is critical for normal wound repair and is decreased in diabetic wounds.
Wolf SJ, Audu CO, Joshi A, denDekker A, Melvin WJ, Davis FM, Xing X, Wasikowski R, Tsoi LC, Kunkel SL, Gudjonsson JE, O'Riordan MX, Kahlenberg JM, Gallagher KA. Wolf SJ, et al. Among authors: melvin wj. JCI Insight. 2022 May 9;7(9):e152765. doi: 10.1172/jci.insight.152765. JCI Insight. 2022. PMID: 35358091 Free PMC article.
Dextran-Mimetic Quantum Dots for Multimodal Macrophage Imaging In Vivo, Ex Vivo, and In Situ.
Deng H, Konopka CJ, Prabhu S, Sarkar S, Medina NG, Fayyaz M, Arogundade OH, Vidana Gamage HE, Shahoei SH, Nall D, Youn Y, Dobrucka IT, Audu CO, Joshi A, Melvin WJ, Gallagher KA, Selvin PR, Nelson ER, Dobrucki LW, Swanson KS, Smith AM. Deng H, et al. Among authors: melvin wj. ACS Nano. 2022 Feb 22;16(2):1999-2012. doi: 10.1021/acsnano.1c07010. Epub 2022 Feb 2. ACS Nano. 2022. PMID: 35107994 Free PMC article.
Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound Repair.
Davis FM, denDekker A, Kimball A, Joshi AD, El Azzouny M, Wolf SJ, Obi AT, Lipinski J, Gudjonsson JE, Xing X, Plazyo O, Audu C, Melvin WJ, Singer K, Henke PK, Moore BB, Burant C, Kunkel SL, Gallagher KA. Davis FM, et al. Among authors: melvin wj. J Immunol. 2020 May 1;204(9):2503-2513. doi: 10.4049/jimmunol.1901263. Epub 2020 Mar 23. J Immunol. 2020. PMID: 32205424 Free PMC article.
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