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Did you mean wen lei tu (81 results)?
Salvianolic acid B ameliorates retinal deficits in an early-stage Alzheimer's disease mouse model through downregulating BACE1 and Aβ generation.
Wang MD, Zhang S, Liu XY, Wang PP, Zhu YF, Zhu JR, Lv CS, Li SY, Liu SF, Wen L. Wang MD, et al. Acta Pharmacol Sin. 2023 Nov;44(11):2151-2168. doi: 10.1038/s41401-023-01125-3. Epub 2023 Jul 7. Acta Pharmacol Sin. 2023. PMID: 37420104
Salvianolic acid B (Sal B), a bioactive compound isolated from the traditional Chinese medicinal herb Salvia miltiorrhiza, has been shown promise in treating neurodegenerative diseases, such as AD and Parkinson's disease. In this study we investigated the therapeutic effec …
Salvianolic acid B (Sal B), a bioactive compound isolated from the traditional Chinese medicinal herb Salvia miltiorrhiza, has been shown pr …
Amelioration of olfactory dysfunction in a mouse model of Parkinson's disease via enhancing GABAergic signaling.
Liu XY, Wang K, Deng XH, Wei YH, Guo R, Liu SF, Zhu YF, Zhong JJ, Zheng JY, Wang MD, Ye QH, He JQ, Guo KH, Zhu JR, Huang SQ, Chen ZX, Lv CS, Wen L. Liu XY, et al. Cell Biosci. 2023 Jun 3;13(1):101. doi: 10.1186/s13578-023-01049-9. Cell Biosci. 2023. PMID: 37270503 Free PMC article.
These results highlight the critical role of aberrant GABAergic signaling of OB in early diagnosis and provide a potential therapeutic strategy for early-stage PD....
These results highlight the critical role of aberrant GABAergic signaling of OB in early diagnosis and provide a potential therapeutic …
Scientific and Regulatory Considerations for Generic Complex Drug Products Containing Nanomaterials.
Zheng N, Sun DD, Zou P, Jiang W. Zheng N, et al. AAPS J. 2017 May;19(3):619-631. doi: 10.1208/s12248-017-0044-1. Epub 2017 Jan 23. AAPS J. 2017. PMID: 28116676 Review.
In the past few decades, the development of medicine at the nanoscale has been applied to oral and parenteral dosage forms in a wide range of therapeutic areas to enhance drug delivery and reduce toxicity. An obvious response to these benefits is reflected in higher market …
In the past few decades, the development of medicine at the nanoscale has been applied to oral and parenteral dosage forms in a wide range o …
Challenges and opportunities in the development of complex generic long-acting injectable drug products.
O'Brien MN, Jiang W, Wang Y, Loffredo DM. O'Brien MN, et al. J Control Release. 2021 Aug 10;336:144-158. doi: 10.1016/j.jconrel.2021.06.017. Epub 2021 Jun 11. J Control Release. 2021. PMID: 34126170 Review.
Long-acting injectable (LAI) drug products enable the controlled release of a drug over an extended duration of time to improve the therapeutic effect, safety profile, or administration of an injectable product. ...
Long-acting injectable (LAI) drug products enable the controlled release of a drug over an extended duration of time to improve the thera …
A review on the phytochemistry and pharmacology of the herb Scoparia dulcis L. for the potential treatment of metabolic syndrome.
Jiang Z, Sung J, Wang X, Zhang Y, Wang Y, Zhou H, Wen L. Jiang Z, et al. RSC Adv. 2021 Sep 22;11(50):31235-31259. doi: 10.1039/d1ra05090g. eCollection 2021 Sep 21. RSC Adv. 2021. PMID: 35496836 Free PMC article. Review.
Therefore, S. dulcis provides new potential for medicine given its numerous therapeutic properties and can be promoted as a complementary or alternative therapy for patients with chronic conditions....
Therefore, S. dulcis provides new potential for medicine given its numerous therapeutic properties and can be promoted as a complemen …
Ginsenoside Rb1 confers neuroprotection via promotion of glutamate transporters in a mouse model of Parkinson's disease.
Zhang YL, Liu Y, Kang XP, Dou CY, Zhuo RG, Huang SQ, Peng L, Wen L. Zhang YL, et al. Neuropharmacology. 2018 Mar 15;131:223-237. doi: 10.1016/j.neuropharm.2017.12.012. Epub 2017 Dec 12. Neuropharmacology. 2018. PMID: 29241654 Free article.
These results indicate that Rb1 suppresses glutamate excitotoxicity and modulates synaptic transmission to improve the impairments in motor functions of the MPTP model of PD, suggesting that Rb1 may serve as a potential therapeutic agent for PD....
These results indicate that Rb1 suppresses glutamate excitotoxicity and modulates synaptic transmission to improve the impairments in motor …
11 results