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Thymoquinone loaded in nanostructured lipid carrier showed enhanced anticancer activity in 4T1 tumor-bearing mice.
Nanomedicine (Lond). 2018 Jul;13(13):1567-1582. doi: 10.2217/nnm-2017-0322.
Nanomedicine (Lond). 2018.
PMID: 30028248
Acute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice.
Ong YS, Saiful Yazan L, Ng WK, Noordin MM, Sapuan S, Foo JB, Tor YS.
Ong YS, et al. Among authors: ng wk.
Int J Nanomedicine. 2016 Nov 9;11:5905-5915. doi: 10.2147/IJN.S114205. eCollection 2016.
Int J Nanomedicine. 2016.
PMID: 27877037
Free PMC article.
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Thymoquinone-loaded nanostructured lipid carrier exhibited cytotoxicity towards breast cancer cell lines (MDA-MB-231 and MCF-7) and cervical cancer cell lines (HeLa and SiHa).
Ng WK, Saiful Yazan L, Yap LH, Wan Nor Hafiza WA, How CW, Abdullah R.
Ng WK, et al.
Biomed Res Int. 2015;2015:263131. doi: 10.1155/2015/263131. Epub 2015 Jan 6.
Biomed Res Int. 2015.
PMID: 25632388
Free PMC article.
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Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein.
Ng WK, Yazan LS, Ismail M.
Ng WK, et al.
Toxicol In Vitro. 2011 Oct;25(7):1392-8. doi: 10.1016/j.tiv.2011.04.030. Epub 2011 May 15.
Toxicol In Vitro. 2011.
PMID: 21609759
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Pharmacokinetics and Biodistribution of Thymoquinone-loaded Nanostructured Lipid Carrier After Oral and Intravenous Administration into Rats.
Zakarial Ansar FH, Latifah SY, Wan Kamal WHB, Khong KC, Ng Y, Foong JN, Gopalsamy B, Ng WK, How CW, Ong YS, Abdullah R, Aziz MY.
Zakarial Ansar FH, et al. Among authors: ng wk.
Int J Nanomedicine. 2020 Oct 9;15:7703-7717. doi: 10.2147/IJN.S262395. eCollection 2020.
Int J Nanomedicine. 2020.
PMID: 33116496
Free PMC article.
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