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2013 1
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Showing results for wangjun tu
Search for Wanjun Tu instead (1 results)
Individualized tumor-informed circulating tumor DNA analysis for postoperative monitoring of non-small cell lung cancer.
Chen K, Yang F, Shen H, Wang C, Li X, Chervova O, Wu S, Qiu F, Peng D, Zhu X, Chuai S, Beck S, Kanu N, Carbone D, Zhang Z, Wang J. Chen K, et al. Cancer Cell. 2023 Oct 9;41(10):1749-1762.e6. doi: 10.1016/j.ccell.2023.08.010. Epub 2023 Sep 7. Cancer Cell. 2023. PMID: 37683638
We report a personalized tumor-informed technology, Patient-specific pROgnostic and Potential tHErapeutic marker Tracking (PROPHET) using deep sequencing of 50 patient-specific variants to detect molecular residual disease (MRD) with a limit of detection of 0.004%. ...
We report a personalized tumor-informed technology, Patient-specific pROgnostic and Potential tHErapeutic marker Tracking (PROPHET) u …
Microbiome and tryptophan metabolomics analysis in adolescent depression: roles of the gut microbiota in the regulation of tryptophan-derived neurotransmitters and behaviors in human and mice.
Zhou M, Fan Y, Xu L, Yu Z, Wang S, Xu H, Zhang J, Zhang L, Liu W, Wu L, Yu J, Yao H, Wang J, Gao R. Zhou M, et al. Microbiome. 2023 Jun 30;11(1):145. doi: 10.1186/s40168-023-01589-9. Microbiome. 2023. PMID: 37386523 Free PMC article.
CONCLUSIONS: This study is the first to delineate the beneficial effects of Ri. on adolescent depression by balancing Trp-derived neurotransmitter metabolism and improving synaptogenesis and glial maintenance, which may yield novel insights into the microbial markers and thera …
CONCLUSIONS: This study is the first to delineate the beneficial effects of Ri. on adolescent depression by balancing Trp-derived neurotrans …
Protection of Oxygen Glucose Deprivation-Induced Human Brain Vascular Pericyte Injury: Beneficial Effects of Bellidifolin in Cellular Pyroptosis.
An D, Xu W, Ge Y, Ge Y, Zhang L, Zhu Y, Zhang Z, Fan J, Gao R, Jiang L, Huang P, Wang J, Chen X. An D, et al. Neurochem Res. 2023 Sep;48(9):2794-2807. doi: 10.1007/s11064-023-03943-7. Epub 2023 May 2. Neurochem Res. 2023. PMID: 37127800
Overall, these findings unravel the potential mechanisms of pericyte injury induced by OGD and indicate that bellidifolin may exert its beneficial effects on pyroptosis, thus providing new therapeutic insights into stroke....
Overall, these findings unravel the potential mechanisms of pericyte injury induced by OGD and indicate that bellidifolin may exert its bene …
Key roles of autophagosome/endosome maturation mediated by Syntaxin17 in methamphetamine-induced neuronal damage in mice.
Wang X, Hu M, Chen J, Lou X, Zhang H, Li M, Cheng J, Ma T, Xiong J, Gao R, Chen X, Wang J. Wang X, et al. Mol Med. 2024 Jan 3;30(1):4. doi: 10.1186/s10020-023-00765-9. Mol Med. 2024. PMID: 38172666 Free PMC article.
CONCLUSION: Stx17 decrease mediated by Meth contributes to vesicle fusion defects which may ascribe to the immature autophagosomes and endosomes, leading to autophagic dysfunction and finalizes neuronal damage and cognitive impairments. Therefore, targeting Stx17 may be a novel …
CONCLUSION: Stx17 decrease mediated by Meth contributes to vesicle fusion defects which may ascribe to the immature autophagosomes and endos …
Mystery of bisphenol F-induced nonalcoholic fatty liver disease-like changes: Roles of Drp1-mediated abnormal mitochondrial fission in lipid droplet deposition.
Zhang L, Xie X, Tao J, Wang S, Hu M, Wang X, Yu Z, Xu L, Lin Y, Wu W, Cheng J, Wu L, Liu W, Gao R, Wang J. Zhang L, et al. Sci Total Environ. 2023 Dec 15;904:166831. doi: 10.1016/j.scitotenv.2023.166831. Epub 2023 Sep 6. Sci Total Environ. 2023. PMID: 37683851
Therefore, targeted intervention against mitochondrial dysfunction may be a promising therapeutic strategy for BPF-induced NAFLD-like changes....
Therefore, targeted intervention against mitochondrial dysfunction may be a promising therapeutic strategy for BPF-induced NAFLD-like …
The Circular RNA circPRKCI Promotes Tumor Growth in Lung Adenocarcinoma.
Qiu M, Xia W, Chen R, Wang S, Xu Y, Ma Z, Xu W, Zhang E, Wang J, Fang T, Hu J, Dong G, Yin R, Wang J, Xu L. Qiu M, et al. Cancer Res. 2018 Jun 1;78(11):2839-2851. doi: 10.1158/0008-5472.CAN-17-2808. Epub 2018 Mar 27. Cancer Res. 2018. PMID: 29588350
In summary, circPRKCI is crucial for tumorigenesis and may serve as a potential therapeutic target in patients with lung adenocarcinoma.Significance: These findings reveal high expression of the circular RNA circPRKCI drives lung adenocarcinoma tumorigenesis. ...
In summary, circPRKCI is crucial for tumorigenesis and may serve as a potential therapeutic target in patients with lung adenocarcino …
Involvement of calcium/calmodulin-dependent protein kinase II in methamphetamine-induced neural damage.
Chen X, Xing J, Jiang L, Qian W, Wang Y, Sun H, Wang Y, Xiao H, Wang J, Zhang J. Chen X, et al. J Appl Toxicol. 2016 Nov;36(11):1460-7. doi: 10.1002/jat.3301. Epub 2016 Feb 29. J Appl Toxicol. 2016. PMID: 26923100
Collectively, our results suggest that Ca(2) (+) -CaM-CaMKII is involved in METH-mediated neurotoxicity, and it might suggest a potential target for the development of therapeutic strategies for METH abuse. Copyright 2016 John Wiley & Sons, Ltd....
Collectively, our results suggest that Ca(2) (+) -CaM-CaMKII is involved in METH-mediated neurotoxicity, and it might suggest a potential ta …
Involvement of water channel Aquaporin 5 in H2S-induced pulmonary edema.
Xu C, Jiang L, Zou Y, Xing J, Sun H, Zhu B, Zhang H, Wang J, Zhang J. Xu C, et al. Environ Toxicol Pharmacol. 2017 Jan;49:202-211. doi: 10.1016/j.etap.2016.12.013. Epub 2016 Dec 30. Environ Toxicol Pharmacol. 2017. PMID: 28088675
Therefore, adjusting AQP5 protein levels could be considered a therapeutic strategy for the treatment of APE induced by H(2)S and other hazardous gases....
Therefore, adjusting AQP5 protein levels could be considered a therapeutic strategy for the treatment of APE induced by H(2)S and oth …
MiR-142a-3p and miR-155-5p reduce methamphetamine-induced inflammation: Role of the target protein Peli1.
Yu G, Song Y, Xie C, Tao L, Wan F, Jiang L, Wang J, Tang J. Yu G, et al. Toxicol Appl Pharmacol. 2019 May 1;370:145-153. doi: 10.1016/j.taap.2019.03.019. Epub 2019 Mar 23. Toxicol Appl Pharmacol. 2019. PMID: 30914375
Peli1 is a novel and important E3 ubiquitin-protein ligase contributing to neuroinflammation; targeting Peli1 may thus provide promising therapeutic strategies for neuroinflammation. In addition to the classic MyD88-dependent or MyD88-independent pathways, miRNAs may also …
Peli1 is a novel and important E3 ubiquitin-protein ligase contributing to neuroinflammation; targeting Peli1 may thus provide promising …
29 results