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Showing results for wang hua pan
Search for Wanghua Pan instead (1 results)
KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition.
Pan Y, Han H, Hu H, Wang H, Song Y, Hao Y, Tong X, Patel AS, Misirlioglu S, Tang S, Huang HY, Geng K, Chen T, Karatza A, Sherman F, Labbe KE, Yang F, Chafitz A, Peng C, Guo C, Moreira AL, Velcheti V, Lau SCM, Sui P, Chen H, Diehl JA, Rustgi AK, Bass AJ, Poirier JT, Zhang X, Ji H, Zhang H, Wong KK. Pan Y, et al. Among authors: wang h. Cancer Cell. 2023 Jan 9;41(1):88-105.e8. doi: 10.1016/j.ccell.2022.11.015. Epub 2022 Dec 15. Cancer Cell. 2023. PMID: 36525973 Free PMC article.
These events provoke a robust elevation in the oncogenic RTK-RAS signaling. Combining SHP2 inhibitor SHP099 and pan-ERBB inhibitor afatinib inhibits lung tumor growth in Kmt2d-deficient LUSC murine models and in patient-derived xenografts (PDXs) harboring KMT2D mutations. …
These events provoke a robust elevation in the oncogenic RTK-RAS signaling. Combining SHP2 inhibitor SHP099 and pan-ERBB inhibitor af …
Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals.
Sankar A, Mohammad F, Sundaramurthy AK, Wang H, Lerdrup M, Tatar T, Helin K. Sankar A, et al. Among authors: wang h. Nat Genet. 2022 Jun;54(6):754-760. doi: 10.1038/s41588-022-01091-2. Epub 2022 Jun 6. Nat Genet. 2022. PMID: 35668298
Here, we use CRISPR base editing in mouse embryonic stem cells (mESCs) to address the regulatory role of lysine 27 of histone H3 (H3K27), a substrate for Polycomb repressive complex 2 (PRC2)-mediated methylation and CBP/EP300-mediated acetylation(6,7). By generating pan-H3 …
Here, we use CRISPR base editing in mouse embryonic stem cells (mESCs) to address the regulatory role of lysine 27 of histone H3 (H3K27), a …
Visual impairment and blindness caused by retinal diseases: A nationwide register-based study.
Zhou C, Li S, Ye L, Chen C, Liu S, Yang H, Zhuang P, Liu Z, Jiang H, Han J, Jiang Y, Zhou L, Zhou X, Xiao J, Zhang C, Wen L, Lan C, Wang Y, Sun T, Jiang L, Xie P, Chen F, Liang G, Fu D, Zhang T, Shi X, Song Z, Liu X, Li S, Li P, Xu X, Wei Q, Wang W, Huang X, De Z, Deng A, Ding L, Pan X, Wen H, Zhang Z, Lv H, Zhang J, Tian X, Deng Z, Wang H, Wang F, Wang Y, Zhao H, Fang Y, Wu Y, Wu Y, Shen N, Li B, Li X, Dai H, Zhao N, Sun X, Zheng Z, Liu K, Xu X. Zhou C, et al. Among authors: wang h. J Glob Health. 2023 Nov 3;13:04126. doi: 10.7189/jogh.13.04126. J Glob Health. 2023. PMID: 37921040 Free PMC article.
Multiplexed nanomaterial-assisted laser desorption/ionization for pan-cancer diagnosis and classification.
Zhang H, Zhao L, Jiang J, Zheng J, Yang L, Li Y, Zhou J, Liu T, Xu J, Lou W, Yang W, Tan L, Liu W, Yu Y, Ji M, Xu Y, Lu Y, Li X, Liu Z, Tian R, Hu C, Zhang S, Hu Q, Deng Y, Ying H, Zhong S, Zhang X, Wang Y, Wang H, Bai J, Li X, Duan X. Zhang H, et al. Among authors: wang h. Nat Commun. 2022 Feb 1;13(1):617. doi: 10.1038/s41467-021-26642-9. Nat Commun. 2022. PMID: 35105875 Free PMC article.
By multiplexing mass spectrometry fingerprints from two independent nanostructured matrixes through machine learning for highly sensitive detection and high throughput analysis, we report a laser desorption/ionization (LDI) mass spectrometry-based liquid biopsy for pan-can …
By multiplexing mass spectrometry fingerprints from two independent nanostructured matrixes through machine learning for highly sensitive de …
128 results