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Characterization of an In Vitro/Ex Vivo Mucoadhesiveness Measurement Method of PVA Films.
Müller L, Rosenbaum C, Krause J, Weitschies W. Müller L, et al. Polymers (Basel). 2022 Nov 26;14(23):5146. doi: 10.3390/polym14235146. Polymers (Basel). 2022. PMID: 36501540 Free PMC article.
The influence of tissue preparation was investigated in ex vivo experiments on porcine small intestinal tissue. It was found that lower values of F(max) and W(ad) were obtained on processed and fresh tissue than on processed and thawed tissue. ...
The influence of tissue preparation was investigated in ex vivo experiments on porcine small intestinal tissue. It was found that lower valu …
Immediate Release 3D-Printed Tablets Produced Via Fused Deposition Modeling of a Thermo-Sensitive Drug.
Kempin W, Domsta V, Grathoff G, Brecht I, Semmling B, Tillmann S, Weitschies W, Seidlitz A. Kempin W, et al. Pharm Res. 2018 Apr 20;35(6):124. doi: 10.1007/s11095-018-2405-6. Pharm Res. 2018. PMID: 29679157
RESULTS: Tablets with the polymers PEG 6000 and PVP K12 and with a proportion of 10% pantoprazole sodium (w/w) demonstrated a fast drug release that was completed within 29 min or 10 min, respectively. ...
RESULTS: Tablets with the polymers PEG 6000 and PVP K12 and with a proportion of 10% pantoprazole sodium (w/w) demonstrated a …
Biodegradable sirolimus-loaded poly(lactide) nanoparticles as drug delivery system for the prevention of in-stent restenosis in coronary stent application.
Luderer F, Löbler M, Rohm HW, Gocke C, Kunna K, Köck K, Kroemer HK, Weitschies W, Schmitz KP, Sternberg K. Luderer F, et al. J Biomater Appl. 2011 May;25(8):851-75. doi: 10.1177/0885328209360696. Epub 2010 Mar 17. J Biomater Appl. 2011. PMID: 20237179
The scope of this work was to determine the applicability of sirolimus-loaded biodegradable poly(D,L-lactide) (PDLLA) nanoparticles as drug carriers to prevent restenotic processes after stent implantation. The average 250 nm sized 20%(w/w) sirolimus-loaded nanopart …
The scope of this work was to determine the applicability of sirolimus-loaded biodegradable poly(D,L-lactide) (PDLLA) nanoparticles as drug …