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The garlic compound ajoene targets protein folding in the endoplasmic reticulum of cancer cells.
Mol Carcinog. 2016 Aug;55(8):1213-28. doi: 10.1002/mc.22364. Epub 2015 Jul 24.
Mol Carcinog. 2016.
PMID: 26207910
The Cytotoxicity of the Ajoene Analogue BisPMB in WHCO1 Oesophageal Cancer Cells Is Mediated by CHOP/GADD153.
Siyo V, Schäfer G, Hunter R, Grafov A, Grafova I, Nieger M, Katz AA, Parker MI, Kaschula CH.
Siyo V, et al.
Molecules. 2017 May 28;22(6):892. doi: 10.3390/molecules22060892.
Molecules. 2017.
PMID: 28555042
Free PMC article.
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Structure-activity studies on the anti-proliferation activity of ajoene analogues in WHCO1 oesophageal cancer cells.
Kaschula CH, Hunter R, Stellenboom N, Caira MR, Winks S, Ogunleye T, Richards P, Cotton J, Zilbeyaz K, Wang Y, Siyo V, Ngarande E, Parker MI.
Kaschula CH, et al. Among authors: siyo v.
Eur J Med Chem. 2012 Apr;50:236-54. doi: 10.1016/j.ejmech.2012.01.058. Epub 2012 Feb 11.
Eur J Med Chem. 2012.
PMID: 22381354
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