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Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy.
Pandya AD, Jäger E, Bagheri Fam S, Höcherl A, Jäger A, Sincari V, Nyström B, Štěpánek P, Skotland T, Sandvig K, Hrubý M, Mælandsmo GM. Pandya AD, et al. Among authors: sincari v. Int J Nanomedicine. 2019 Aug 6;14:6269-6285. doi: 10.2147/IJN.S208938. eCollection 2019. Int J Nanomedicine. 2019. PMID: 31496685 Free PMC article.
pH-responsive polymersome-mediated delivery of doxorubicin into tumor sites enhances the therapeutic efficacy and reduces cardiotoxic effects.
Albuquerque LJC, Sincari V, Jäger A, Kucka J, Humajova J, Pankrac J, Paral P, Heizer T, Janouškova O, Davidovich I, Talmon Y, Pouckova P, Štěpánek P, Sefc L, Hruby M, Giacomelli FC, Jäger E. Albuquerque LJC, et al. Among authors: sincari v. J Control Release. 2021 Apr 10;332:529-538. doi: 10.1016/j.jconrel.2021.03.013. Epub 2021 Mar 12. J Control Release. 2021. PMID: 33716094
Tuning the morphology of block copolymer-based pH-triggered nanoplatforms as driven by changes in molecular weight and protocol of manufacturing.
de Oliveira FA, C S Batista C, J C Albuquerque L, Černoch P, Steinhart M, Sincari V, Jager A, Jager E, Giacomelli FC. de Oliveira FA, et al. Among authors: sincari v. J Colloid Interface Sci. 2023 Apr;635:406-416. doi: 10.1016/j.jcis.2022.12.129. Epub 2022 Dec 28. J Colloid Interface Sci. 2023. PMID: 36599239
Reactive Oxygen Species (ROS)-Responsive Polymersomes with Site-Specific Chemotherapeutic Delivery into Tumors via Spacer Design Chemistry.
Jäger E, Sincari V, Albuquerque LJC, Jäger A, Humajova J, Kucka J, Pankrac J, Paral P, Heizer T, Janouskova O, Konefał R, Pavlova E, Sedlacek O, Giacomelli FC, Pouckova P, Sefc L, Stepanek P, Hruby M. Jäger E, et al. Among authors: sincari v. Biomacromolecules. 2020 Apr 13;21(4):1437-1449. doi: 10.1021/acs.biomac.9b01748. Epub 2020 Mar 4. Biomacromolecules. 2020. PMID: 32083473
Microfluidic-Assisted Engineering of Quasi-Monodisperse pH-Responsive Polymersomes toward Advanced Platforms for the Intracellular Delivery of Hydrophilic Therapeutics.
Albuquerque LJC, Sincari V, Ja Ger A, Konefa R, Pa Nek JI, C Ernoch P, Pavlova E, S Te Pa Nek P, Giacomelli FC, Ja Ger EZ. Albuquerque LJC, et al. Among authors: sincari v. Langmuir. 2019 Jun 25;35(25):8363-8372. doi: 10.1021/acs.langmuir.9b01009. Epub 2019 Jun 14. Langmuir. 2019. PMID: 31199159