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Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach.
Mitrović JR, Divović-Matović B, Knutson DE, Đoković JB, Kremenović A, Dobričić VD, Randjelović DV, Pantelić I, Cook JM, Savić MM, Savić SD. Mitrović JR, et al. Among authors: dobricic vd. Pharmaceutics. 2021 Jul 31;13(8):1188. doi: 10.3390/pharmaceutics13081188. Pharmaceutics. 2021. PMID: 34452149 Free PMC article.
High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances.
Mitrović JR, Divović-Matović B, Knutson DE, Petković M, Djorović D, Randjelović DV, Dobričić VD, Đoković JB, Lunter DJ, Cook JM, Savić MM, Savić SD. Mitrović JR, et al. Among authors: dobricic vd. Int J Pharm. 2023 Feb 25;633:122613. doi: 10.1016/j.ijpharm.2023.122613. Epub 2023 Jan 16. Int J Pharm. 2023. PMID: 36657554 Free PMC article.
Nanocrystal dispersion of DK-I-56-1, a poorly soluble pyrazoloquinolinone positive modulator of α6 GABAA receptors: Formulation approach toward improved in vivo performance.
Mitrović JR, Divović B, Knutson DE, Đoković JB, Vulić PJ, Randjelović DV, Dobričić VD, Čalija BR, Cook JM, Savić MM, Savić SD. Mitrović JR, et al. Among authors: dobricic vd. Eur J Pharm Sci. 2020 Sep 1;152:105432. doi: 10.1016/j.ejps.2020.105432. Epub 2020 Jun 18. Eur J Pharm Sci. 2020. PMID: 32565331 Free PMC article.
Alkyl polyglucoside vs. ethoxylated surfactant-based microemulsions as vehicles for two poorly water-soluble drugs: physicochemical characterization and in vivo skin performance.
Pajić NZB, Todosijević MN, Vuleta GM, Cekić ND, Dobričić VD, Vučen SR, Čalija BR, Lukić MŽ, Ilić TM, Savić SD. Pajić NZB, et al. Among authors: dobricic vd. Acta Pharm. 2017 Dec 20;67(4):415-439. doi: 10.1515/acph-2017-0036. Acta Pharm. 2017. PMID: 29337676 Free article.