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Transcriptional profiles of adjuvanted hepatitis B vaccines display variable interindividual homogeneity but a shared core signature.
De Mot L, Bechtold V, Bol V, Callegaro A, Coccia M, Essaghir A, Hasdemir D, Ulloa-Montoya F, Siena E, Smilde A, van den Berg RA, Didierlaurent AM, Burny W, van der Most RG. De Mot L, et al. Among authors: bechtold v. Sci Transl Med. 2020 Nov 11;12(569):eaay8618. doi: 10.1126/scitranslmed.aay8618. Sci Transl Med. 2020. PMID: 33177181
Systems analysis of human responses to an aluminium hydroxide-adsorbed TLR7 agonist (AS37) adjuvanted vaccine reveals a dose-dependent and specific activation of the interferon-mediated antiviral response.
Siena E, Schiavetti F, Borgogni E, Taccone M, Faenzi E, Brazzoli M, Aprea S, Bardelli M, Volpini G, Buricchi F, Sammicheli C, Tavarini S, Bechtold V, Blohmke CJ, Cardamone D, De Intinis C, Gonzalez-Lopez A, O'Hagan DT, Nuti S, Seidl C, Didierlaurent AM, Bertholet S, D'Oro U, Medini D, Finco O. Siena E, et al. Among authors: bechtold v. Vaccine. 2023 Jan 16;41(3):724-734. doi: 10.1016/j.vaccine.2022.12.006. Epub 2022 Dec 21. Vaccine. 2023. PMID: 36564274 Free article. Clinical Trial.
Molecular Signature of Monocytes Shaped by the Shigella sonnei 1790-Generalized Modules for Membrane Antigens Vaccine.
Tondi S, Siena E, Essaghir A, Bozzetti B, Bechtold V, Scaillet A, Clemente B, Marrocco M, Sammicheli C, Tavarini S, Micoli F, Oldrini D, Pezzicoli A, Di Fede M, Brazzoli M, Ulivieri C, Schiavetti F. Tondi S, et al. Among authors: bechtold v. Int J Mol Sci. 2024 Jan 17;25(2):1116. doi: 10.3390/ijms25021116. Int J Mol Sci. 2024. PMID: 38256189 Free PMC article.
Lysosome-Dependent Activation of Human Dendritic Cells by the Vaccine Adjuvant QS-21.
Welsby I, Detienne S, N'Kuli F, Thomas S, Wouters S, Bechtold V, De Wit D, Gineste R, Reinheckel T, Elouahabi A, Courtoy PJ, Didierlaurent AM, Goriely S. Welsby I, et al. Among authors: bechtold v. Front Immunol. 2017 Jan 5;7:663. doi: 10.3389/fimmu.2016.00663. eCollection 2016. Front Immunol. 2017. PMID: 28105029 Free PMC article.
Adjuvant-Associated Peripheral Blood mRNA Profiles and Kinetics Induced by the Adjuvanted Recombinant Protein Candidate Tuberculosis Vaccine M72/AS01 in Bacillus Calmette-Guérin-Vaccinated Adults.
van den Berg RA, De Mot L, Leroux-Roels G, Bechtold V, Clement F, Coccia M, Jongert E, Evans TG, Gillard P, van der Most RG. van den Berg RA, et al. Among authors: bechtold v. Front Immunol. 2018 Mar 26;9:564. doi: 10.3389/fimmu.2018.00564. eCollection 2018. Front Immunol. 2018. PMID: 29632533 Free PMC article. Clinical Trial.
Different Adjuvants Induce Common Innate Pathways That Are Associated with Enhanced Adaptive Responses against a Model Antigen in Humans.
Burny W, Callegaro A, Bechtold V, Clement F, Delhaye S, Fissette L, Janssens M, Leroux-Roels G, Marchant A, van den Berg RA, Garçon N, van der Most R, Didierlaurent AM; ECR-002 Study Group. Burny W, et al. Among authors: bechtold v. Front Immunol. 2017 Aug 14;8:943. doi: 10.3389/fimmu.2017.00943. eCollection 2017. Front Immunol. 2017. PMID: 28855902 Free PMC article.