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Showing results for vitro l. Gontijo
Your search for Vitor L. Gontijo retrieved no results
In Vitro Study of Cytotoxic Mechanisms of Alkylphospholipids and Alkyltriazoles in Acute Lymphoblastic Leukemia Models.
Jesus LOP, de Souza AA, Torquato HFV, Gontijo VS, Pereira de Freitas R, Gesteira TF, Coulson-Thomas VJ, Torquato RJS, Tanaka AS, Paredes-Gamero EJ, Judice WAS. Jesus LOP, et al. Molecules. 2022 Dec 6;27(23):8633. doi: 10.3390/molecules27238633. Molecules. 2022. PMID: 36500726 Free PMC article.
The inhibitory potential and mechanism of inhibition of cathepsins B and L, molecular docking simulation, molecular dynamics and binding free energy evaluation were performed to determine the interaction of cathepsins and compounds. ...Bax inhibitor, Z-VAD-FMK, pepstatin, …
The inhibitory potential and mechanism of inhibition of cathepsins B and L, molecular docking simulation, molecular dynamics and bind …
Synthesis and evaluation of the antileishmanial activity of silver compounds containing imidazolidine-2-thione.
Espuri PF, Dos Reis LL, de Figueiredo Peloso E, Gontijo VS, Colombo FA, Nunes JB, de Oliveira CE, De Almeida ET, Silva DES, Bortoletto J, Segura DF, Netto AVG, Marques MJ. Espuri PF, et al. J Biol Inorg Chem. 2019 May;24(3):419-432. doi: 10.1007/s00775-019-01657-2. Epub 2019 Apr 4. J Biol Inorg Chem. 2019. PMID: 30949838
The compounds [Ag(phen)(imzt)]NO(3)(1), [Ag(phen)(imzt)]CF(3)SO(3)(2), [Ag(phen)(2)](BF(4)).H(2)O (3), [Ag(2)(imzt)(6)](NO(3))(2)(4), and imzt have been synthesized and evaluated in vitro for antileishmanial activity against Leishmania. (L.) amazonensis (La) and …
The compounds [Ag(phen)(imzt)]NO(3)(1), [Ag(phen)(imzt)]CF(3)SO(3)(2), [Ag(phen)(2)](BF(4)).H(2)O (3), [Ag(2)(imzt)(6)](NO(3))(2)(4), and im …
Intraspecies susceptibility of Leishmania (Viannia) braziliensis to antileishmanial drugs: Antimony resistance in human isolates from atypical lesions.
Rugani JN, Quaresma PF, Gontijo CF, Soares RP, Monte-Neto RL. Rugani JN, et al. Biomed Pharmacother. 2018 Dec;108:1170-1180. doi: 10.1016/j.biopha.2018.09.149. Epub 2018 Oct 2. Biomed Pharmacother. 2018. PMID: 30372818 Free article.
Refractory cases are not necessarily due to intrinsic parasite drug resistance. The status of in vitro drug susceptibility from L. braziliensis field isolates is less assessed than patient treatment outcome. ...L. braziliensis promastigotes isolated from AT l …
Refractory cases are not necessarily due to intrinsic parasite drug resistance. The status of in vitro drug susceptibility from L …
In vivo evaluation of anti-Leishmania activity of alkyltriazoles and alkylphosphocholines by oral route.
Gontijo VS, Colombo FA, Ferreira Espuri P, Freitas PG, Nunes JB, Alves LB, Veloso MP, Alves RB, Freitas RP, Marques MJ. Gontijo VS, et al. Exp Parasitol. 2021 Jul-Aug;226-227:108123. doi: 10.1016/j.exppara.2021.108123. Epub 2021 Jun 16. Exp Parasitol. 2021. PMID: 34144040 Free article.
The high activity levels of these compounds in vivo may stem from their high in vitro leishmanicidal activity and lipophilicity. The in silico absorption, distribution, metabolism, and excretion studies also showed some anti-Leishmania potential. ...In silico studies of th …
The high activity levels of these compounds in vivo may stem from their high in vitro leishmanicidal activity and lipophilicity. The …
Cytotoxicity and inhibition of platelet aggregation caused by an l-amino acid oxidase from Bothrops leucurus venom.
Naumann GB, Silva LF, Silva L, Faria G, Richardson M, Evangelista K, Kohlhoff M, Gontijo CM, Navdaev A, de Rezende FF, Eble JA, Sanchez EF. Naumann GB, et al. Biochim Biophys Acta. 2011 Jul;1810(7):683-94. doi: 10.1016/j.bbagen.2011.04.003. Epub 2011 Apr 22. Biochim Biophys Acta. 2011. PMID: 21539897 Free article.
BACKGROUND: Multifunctional l-amino acid oxidases (LAAOs) occur widely in snake venoms. METHODS: The l-AAO from Bothrops leucurus (Bl-LAAO) venom was purified using a combination of molecular exclusion and ion-exchange chromatographies. ...Its N-terminal sequence sh …
BACKGROUND: Multifunctional l-amino acid oxidases (LAAOs) occur widely in snake venoms. METHODS: The l-AAO from Bothrops leucu …
A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden.
Roatt BM, Aguiar-Soares RD, Reis LE, Cardoso JM, Mathias FA, de Brito RC, da Silva SM, Gontijo NF, Ferreira SA, Valenzuela JG, Corrêa-Oliveira R, Giunchetti RC, Reis AB. Roatt BM, et al. Front Immunol. 2017 Mar 7;8:217. doi: 10.3389/fimmu.2017.00217. eCollection 2017. Front Immunol. 2017. PMID: 28321217 Free PMC article.
Sixteen dogs received immunotherapy with MPL adjuvant (n = 6) or with a vaccine composed of antigens of L. braziliensis associated with MPL (LBMPL vaccine therapy, n = 10). ...In addition, in an ex vivo analysis using flow cytometry, dogs treated with LBMPL vaccine showed …
Sixteen dogs received immunotherapy with MPL adjuvant (n = 6) or with a vaccine composed of antigens of L. braziliensis associated wi …