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Page 1
Showing results for vitro ames
Search for Vitor Anes instead (2 results)
Genotoxicity of Nanocarriers.
Luo T, Gao L, Chen X, Xu K, Niu M. Luo T, et al. Curr Drug Metab. 2018;19(2):110-123. doi: 10.2174/1389200218666171031122346. Curr Drug Metab. 2018. PMID: 29086685 Review.
A total of 45 publications were included. In these studies, the in vitro and in vivo Comet assay, in vitro and in vivo micronucleus assay, in vitro and in vivo Chromosomal Aberration (CA) assay, Ames test, phosphorylated histone H2Ax (gamma-H2Ax) foci …
A total of 45 publications were included. In these studies, the in vitro and in vivo Comet assay, in vitro and in vivo micronu …
Lack of genotoxicity of rhubarb (rhizome) in the Ames and micronucleus in vitro tests.
Melzi G, Galli CL, Ciliutti P, Marabottini C, Marinovich M. Melzi G, et al. Toxicol Rep. 2022 Jul 30;9:1574-1579. doi: 10.1016/j.toxrep.2022.07.017. eCollection 2022. Toxicol Rep. 2022. PMID: 36518439 Free PMC article.
In the present study, Rhubarb ethanolic extract of ground rhubarb rhizome (hydroxyanthracene total content 1.39 %) was tested in the Ames Assay in Salmonella typhimurium and Escherichia coli, up to 5000 g/plate and up to 5000 g/mL in human lymphocytes Micronucleus Test (OE …
In the present study, Rhubarb ethanolic extract of ground rhubarb rhizome (hydroxyanthracene total content 1.39 %) was tested in the Ames …
In vivo and in vitro mutagenicity of perillaldehyde and cinnamaldehyde.
Honma M, Yamada M, Yasui M, Horibata K, Sugiyama KI, Masumura K. Honma M, et al. Genes Environ. 2021 Jul 16;43(1):30. doi: 10.1186/s41021-021-00204-3. Genes Environ. 2021. PMID: 34271990 Free PMC article.
To clarify the mutagenicity of perillaldehyde and cinnamaldehyde, we conducted in silico quantitative structure-activity relationship (QSAR) analysis, in vitro Ames tests, and in vivo transgenic rodent gene mutation (TGR) assays. RESULTS: In Ames tests, peril …
To clarify the mutagenicity of perillaldehyde and cinnamaldehyde, we conducted in silico quantitative structure-activity relationship (QSAR) …
Microbial Mutagenicity Assay: Ames Test.
Vijay U, Gupta S, Mathur P, Suravajhala P, Bhatnagar P. Vijay U, et al. Bio Protoc. 2018 Mar 20;8(6):e2763. doi: 10.21769/BioProtoc.2763. eCollection 2018 Mar 20. Bio Protoc. 2018. PMID: 34179285 Free PMC article.
The Microbial mutagenicity Ames test is a bacterial bioassay accomplished in vitro to evaluate the mutagenicity of various environmental carcinogens and toxins. ...We present the protocol for conducting Ames test in the laboratory....
The Microbial mutagenicity Ames test is a bacterial bioassay accomplished in vitro to evaluate the mutagenicity of various env …
In Vitro Genotoxicity Testing: Significance and Use in Environmental Monitoring.
Umbuzeiro GA, Heringa M, Zeiger E. Umbuzeiro GA, et al. Adv Biochem Eng Biotechnol. 2017;157:59-80. doi: 10.1007/10_2015_5018. Adv Biochem Eng Biotechnol. 2017. PMID: 27631084 Review.
However, no less important are the germ cell mutations, because the adverse outcome is related not only to an individual but also to population levels. For environmental analysis the most common choices are in vitro assays, and among them the most widely used is the Ame …
However, no less important are the germ cell mutations, because the adverse outcome is related not only to an individual but also to populat …
A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins.
Kirkland D, Reeve L, Gatehouse D, Vanparys P. Kirkland D, et al. Mutat Res. 2011 Mar 18;721(1):27-73. doi: 10.1016/j.mrgentox.2010.12.015. Epub 2011 Jan 14. Mutat Res. 2011. PMID: 21238603
Published in vitro data from at least one test system (most were from the Ames test) were available for 557 carcinogens and 405 in vivo genotoxins. ...Thus, there is no convincing evidence that any genotoxic rodent carcinogens or in vivo genotoxins would remain unde …
Published in vitro data from at least one test system (most were from the Ames test) were available for 557 carcinogens and 40 …
Hydromorphone impurity 2,2-bishydromorphone does not exert mutagenic and clastogenic properties via in silico QSAR prediction and in vitro Ames and micronucleus test.
Franckenstein D, Bothe MK, Hurtado SB, Westphal M. Franckenstein D, et al. Drug Chem Toxicol. 2023 Nov;46(4):634-639. doi: 10.1080/01480545.2022.2076866. Epub 2022 May 23. Drug Chem Toxicol. 2023. PMID: 35603474
In this study, 2,2-bishydromorphone was tested in silico and in vitro for both its mutagenic potential in an Ames test performed with Salmonella typhimurium and Escherichia coli tester strains up to a maximum concentration of 5 mg per plate in the absence and presen …
In this study, 2,2-bishydromorphone was tested in silico and in vitro for both its mutagenic potential in an Ames test perform …
Overcoming roadblocks for in vitro nurseries in plants: induction of meiosis.
Cook TM, Isenegger D, Dutta S, Sahab S, Kay P, Aboobucker SI, Biswas E, Heerschap S, Nikolau BJ, Dong L, Lübberstedt T. Cook TM, et al. Front Plant Sci. 2023 Jun 2;14:1204813. doi: 10.3389/fpls.2023.1204813. eCollection 2023. Front Plant Sci. 2023. PMID: 37332695 Free PMC article. Review.
It has been proposed that the rate of genetic gain can be increased by reducing the time between generations by circumventing flowering through the in vitro induction of meiosis. In this review, we assess technologies and approaches that may offer a path towards meiosis in …
It has been proposed that the rate of genetic gain can be increased by reducing the time between generations by circumventing flowering thro …
Revisiting the mutagenicity and genotoxicity of N-nitroso propranolol in bacterial and human in vitro assays.
Li X, Le Y, Seo JE, Guo X, Li Y, Chen S, Mittelstaedt RA, Moore N, Guerrero S, Sims A, King ST, Atrakchi AH, McGovern TJ, Davis-Bruno KL, Keire DA, Elespuru RK, Heflich RH, Mei N. Li X, et al. Regul Toxicol Pharmacol. 2023 Jun;141:105410. doi: 10.1016/j.yrtph.2023.105410. Epub 2023 May 18. Regul Toxicol Pharmacol. 2023. PMID: 37210026
NNP has been reported to be negative in the bacterial reverse mutation test (the Ames test) but genotoxic in other in vitro assays. In the current study, we systematically examined the in vitro mutagenicity and genotoxicity of NNP using several modifications …
NNP has been reported to be negative in the bacterial reverse mutation test (the Ames test) but genotoxic in other in vitro as …
In vitro evaluation of mutagenic, cytotoxic, genotoxic and oral irritation potential of nicotine pouch products.
Miller-Holt J, Baskerville-Abraham I, Sakimura M, Fukushima T, Puglisi A, Gafner J. Miller-Holt J, et al. Toxicol Rep. 2022 Jun 15;9:1316-1324. doi: 10.1016/j.toxrep.2022.06.008. eCollection 2022. Toxicol Rep. 2022. PMID: 36518473 Free PMC article.
In vitro investigations were conducted in the Neutral Red Uptake (NRU) cytotoxicity assay, Bacterial Reverse Mutation (Ames) assay, and in vitro Mammalian Cell Micronucleus (ivMN) assay. These products were also investigated for their oral irritation potentia …
In vitro investigations were conducted in the Neutral Red Uptake (NRU) cytotoxicity assay, Bacterial Reverse Mutation (Ames) a …
3,357 results