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The following term was not found in PubMed: Giziene
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Wallace M, Gillispie-Bell V, Cruz K, Davis K, Vilda D. Wallace M, et al. Obstet Gynecol. 2022 Apr 1;139(4):692. doi: 10.1097/AOG.0000000000004738. Obstet Gynecol. 2022. PMID: 35594125 Free PMC article. No abstract available.
Vildagliptin restores cognitive function and mitigates hippocampal neuronal apoptosis in cisplatin-induced chemo-brain: Imperative roles of AMPK/Akt/CREB/ BDNF signaling cascades.
Mahmoud AMA, Mantawy EM, Wahdan SA, Ammar RM, El-Demerdash E. Mahmoud AMA, et al. Biomed Pharmacother. 2023 Mar;159:114238. doi: 10.1016/j.biopha.2023.114238. Epub 2023 Jan 12. Biomed Pharmacother. 2023. PMID: 36640673 Free article.
The results revealed that Vilda restored the cognitive function impaired by CP, as assessed by the Morris water maze, Y-maze, and passive avoidance tests. ...Notably, Vilda boosted cholinergic neurotransmission through the downregulation of the acetylcholinesterase …
The results revealed that Vilda restored the cognitive function impaired by CP, as assessed by the Morris water maze, Y-maze, and pas …
Vildagliptin improves neurological function by inhibiting apoptosis and ferroptosis following intracerebral hemorrhage in mice.
Zhang Y, Zhang X, Wee Yong V, Xue M. Zhang Y, et al. Neurosci Lett. 2022 Apr 17;776:136579. doi: 10.1016/j.neulet.2022.136579. Epub 2022 Mar 15. Neurosci Lett. 2022. PMID: 35304193
However, it is not clear whether Vilda has anti-cell death efficacy in ICH. In the present study, the potential neuroprotective effect of Vilda in ICH mice was investigated. ...The activation of microglia/macrophages and infiltration of neutrophil were restrained by …
However, it is not clear whether Vilda has anti-cell death efficacy in ICH. In the present study, the potential neuroprotective effec …
DPP-4 inhibitor induces FGF21 expression via sirtuin 1 signaling and improves myocardial energy metabolism.
Furukawa N, Koitabashi N, Matsui H, Sunaga H, Umbarawan Y, Syamsunarno MRAA, Yamaguchi A, Obokata M, Hanaoka H, Yokoyama T, Kurabayashi M. Furukawa N, et al. Heart Vessels. 2021 Jan;36(1):136-146. doi: 10.1007/s00380-020-01711-z. Epub 2020 Oct 18. Heart Vessels. 2021. PMID: 33073318 Free PMC article.
Mice were treated with either vehicle or vilda, followed by transverse aortic constriction (TAC). After 3 weeks of TAC, cardiac hypertrophy and impairment of systolic function were attenuated in vilda-treated mice. ...Vilda treatment markedly induced FGF21 ex …
Mice were treated with either vehicle or vilda, followed by transverse aortic constriction (TAC). After 3 weeks of TAC, cardiac hyper …
Vildagliptin alleviates liver fibrosis in NASH diabetic rats via modulation of insulin resistance, oxidative stress, and inflammatory cascades.
Hendawy AS, El-Lakkany NM, Mantawy EM, Hammam OA, Botros SS, El-Demerdash E. Hendawy AS, et al. Life Sci. 2022 Sep 1;304:120695. doi: 10.1016/j.lfs.2022.120695. Epub 2022 Jun 4. Life Sci. 2022. PMID: 35671811
Besides, Vilda successfully counteracted NASH-associated liver fibrosis by downregulating the TGF-beta1 pathway. SIGNIFICANCE: The hepatoprotective and antifibrotic effects of Vilda were mostly dose-dependent. Collectively, this study offered a promising therapeutic …
Besides, Vilda successfully counteracted NASH-associated liver fibrosis by downregulating the TGF-beta1 pathway. SIGNIFICANCE: The he …
Vildagliptin Attenuates Huntington's Disease through Activation of GLP-1 Receptor/PI3K/Akt/BDNF Pathway in 3-Nitropropionic Acid Rat Model.
Sayed NH, Fathy N, Kortam MA, Rabie MA, Mohamed AF, Kamel AS. Sayed NH, et al. Neurotherapeutics. 2020 Jan;17(1):252-268. doi: 10.1007/s13311-019-00805-5. Neurotherapeutics. 2020. PMID: 31728850 Free PMC article.
However, Vilda's role in HD is yet to be elucidated. Thus, the aim of the study is to uncover the potentiality of Vilda in HD and unfold its link with PI3K/Akt pathway in 3-nitropropionic acid (3NP) rat model. ...The molecular signaling of Vilda was estimated …
However, Vilda's role in HD is yet to be elucidated. Thus, the aim of the study is to uncover the potentiality of Vilda in HD …
Vildagliptin attenuates acetic acid-induced colitis in rats via targeting PI3K/Akt/NFκB, Nrf2 and CREB signaling pathways and the expression of lncRNA IFNG-AS1 and miR-146a.
Fouad MR, Salama RM, Zaki HF, El-Sahar AE. Fouad MR, et al. Int Immunopharmacol. 2021 Mar;92:107354. doi: 10.1016/j.intimp.2020.107354. Epub 2021 Jan 9. Int Immunopharmacol. 2021. PMID: 33434756
Hence, the current study aimed to explore the possible prophylactic effect of different doses of Vilda against acetic acid (AA)-induced colitis in rats. Forty-eight adult Wistar rats were divided into six groups: control, Vilda (10 mg/kg/day; p.o.), AA, AA + Vild …
Hence, the current study aimed to explore the possible prophylactic effect of different doses of Vilda against acetic acid (AA)-induc …
Vildagliptin, a DPP-4 Inhibitor, Attenuates Endothelial Dysfunction and Atherogenesis in Nondiabetic Apolipoprotein E-Deficient Mice.
Aini K, Fukuda D, Tanaka K, Higashikuni Y, Hirata Y, Yagi S, Kusunose K, Yamada H, Soeki T, Sata M. Aini K, et al. Int Heart J. 2019 Nov 30;60(6):1421-1429. doi: 10.1536/ihj.19-117. Epub 2019 Nov 15. Int Heart J. 2019. PMID: 31735774 Free article.
Eight-week-old nondiabetic ApoE(-/-) mice fed a Western-type diet received Vilda (50 mg/kg/day) for 20 weeks or 8 weeks. After 20 weeks of treatment, Vilda administration reduced atherogenesis in the aortic arch as determined by en face Sudan IV staining compared wi …
Eight-week-old nondiabetic ApoE(-/-) mice fed a Western-type diet received Vilda (50 mg/kg/day) for 20 weeks or 8 weeks. After 20 wee …
Vildagliptin Attenuates Hepatic Ischemia/Reperfusion Injury via the TLR4/NF-κB Signaling Pathway.
Sherif IO, Al-Shaalan NH. Sherif IO, et al. Oxid Med Cell Longev. 2018 Oct 14;2018:3509091. doi: 10.1155/2018/3509091. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 30405876 Free PMC article.
Thus, the purpose of this study was to examine whether pretreatment with vildagliptin (Vilda), a DPP4 inhibitor, produces hepatic protection against IR injury and to investigate its influence on TLR4/NF-kappaB signaling in a rat model. Thirty male Wistar rats were divided …
Thus, the purpose of this study was to examine whether pretreatment with vildagliptin (Vilda), a DPP4 inhibitor, produces hepatic pro …
Impact of vildagliptin on vascular and fibrotic remodeling of myocardium in experimental diabetic cardiomyopathy.
Abdel-Hamid AAM, Firgany AEL. Abdel-Hamid AAM, et al. Acta Histochem. 2020 Feb;122(2):151499. doi: 10.1016/j.acthis.2019.151499. Epub 2019 Dec 28. Acta Histochem. 2020. PMID: 31889531
We divided animals equally into 4 groups; nondiabetic (ND), VILDA per se, DCM and DCM + VILDA and their myocardium was evaluated for the fibro-vascular remodeling immunohistochemically as well as for molecular changes. ...In addition VILDA significantly incre …
We divided animals equally into 4 groups; nondiabetic (ND), VILDA per se, DCM and DCM + VILDA and their myocardium was evaluat …
51 results