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A validated UPLC-MS/MS method for the analysis of linezolid and a novel oxazolidinone derivative (PH027) in plasma and its application to tissue distribution study in rabbits.
Hedaya MA, Thomas V, Abdel-Hamid ME, Kehinde EO, Phillips OA. Hedaya MA, et al. Among authors: thomas v. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Jan 1;1040:89-96. doi: 10.1016/j.jchromb.2016.11.034. Epub 2016 Nov 27. J Chromatogr B Analyt Technol Biomed Life Sci. 2017. PMID: 27978473
Comparative Pharmacokinetic Study for Linezolid and Two Novel Antibacterial Oxazolidinone Derivatives in Rabbits: Can Differences in the Pharmacokinetic Properties Explain the Discrepancies between Their In Vivo and In Vitro Antibacterial Activities?
Hedaya MA, Thomas V, Abdel-Hamid ME, Kehinde EO, Phillips OA. Hedaya MA, et al. Among authors: thomas v. Pharmaceutics. 2017 Sep 7;9(3):34. doi: 10.3390/pharmaceutics9030034. Pharmaceutics. 2017. PMID: 28880210 Free PMC article.