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Page 1
Potassium channel blocker crafted by α-hairpinin scaffold engineering.
Tabakmakher VM, Gigolaev AM, Peigneur S, Krylov NA, Tytgat J, Chugunov AO, Vassilevski AA, Efremov RG. Tabakmakher VM, et al. Biophys J. 2021 Jun 15;120(12):2471-2481. doi: 10.1016/j.bpj.2021.04.020. Epub 2021 Apr 29. Biophys J. 2021. PMID: 33932436 Free PMC article.
Artificial pore blocker acts specifically on voltage-gated potassium channel isoform KV1.6.
Gigolaev AM, Lushpa VA, Pinheiro-Junior EL, Tabakmakher VM, Peigneur S, Ignatova AA, Feofanov AV, Efremov RG, Mineev KS, Tytgat J, Vassilevski AA. Gigolaev AM, et al. Among authors: tabakmakher vm. J Biol Chem. 2022 Nov;298(11):102467. doi: 10.1016/j.jbc.2022.102467. Epub 2022 Sep 8. J Biol Chem. 2022. PMID: 36087839 Free PMC article.
Tuning Scorpion Toxin Selectivity: Switching From KV1.1 to KV1.3.
Gigolaev AM, Kuzmenkov AI, Peigneur S, Tabakmakher VM, Pinheiro-Junior EL, Chugunov AO, Efremov RG, Tytgat J, Vassilevski AA. Gigolaev AM, et al. Among authors: tabakmakher vm. Front Pharmacol. 2020 Jul 7;11:1010. doi: 10.3389/fphar.2020.01010. eCollection 2020. Front Pharmacol. 2020. PMID: 32733247 Free PMC article.
Sea Anemone Kunitz-Type Peptides Demonstrate Neuroprotective Activity in the 6-Hydroxydopamine Induced Neurotoxicity Model.
Sintsova O, Gladkikh I, Monastyrnaya M, Tabakmakher V, Yurchenko E, Menchinskaya E, Pislyagin E, Andreev Y, Kozlov S, Peigneur S, Tytgat J, Aminin D, Kozlovskaya E, Leychenko E. Sintsova O, et al. Among authors: tabakmakher v. Biomedicines. 2021 Mar 10;9(3):283. doi: 10.3390/biomedicines9030283. Biomedicines. 2021. PMID: 33802055 Free PMC article.
Protein surface topography as a tool to enhance the selective activity of a potassium channel blocker.
Berkut AA, Chugunov AO, Mineev KS, Peigneur S, Tabakmakher VM, Krylov NA, Oparin PB, Lihonosova AF, Novikova EV, Arseniev AS, Grishin EV, Tytgat J, Efremov RG, Vassilevski AA. Berkut AA, et al. Among authors: tabakmakher vm. J Biol Chem. 2019 Nov 29;294(48):18349-18359. doi: 10.1074/jbc.RA119.010494. Epub 2019 Sep 18. J Biol Chem. 2019. PMID: 31533989 Free PMC article.
Complex approach for analysis of snake venom α-neurotoxins binding to HAP, the high-affinity peptide.
Kudryavtsev DS, Tabakmakher VМ, Budylin GS, Egorova NS, Efremov RG, Ivanov IA, Belukhina SY, Jegorov AV, Kasheverov IE, Kryukova EV, Shelukhina IV, Shirshin EA, Zhdanova NG, Zhmak MN, Tsetlin VI. Kudryavtsev DS, et al. Among authors: tabakmakher v. Sci Rep. 2020 Mar 2;10(1):3861. doi: 10.1038/s41598-020-60768-y. Sci Rep. 2020. PMID: 32123252 Free PMC article.
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