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64 results

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Page 1
Small-molecule Ca(V)alpha(1)Ca(V)beta antagonist suppresses neuronal voltage-gated calcium-channel trafficking.
Chen X, Liu D, Zhou D, Si Y, Xu D, Stamatkin CW, Ghozayel MK, Ripsch MS, Obukhov AG, White FA, Meroueh SO. Chen X, et al. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10566-E10575. doi: 10.1073/pnas.1813157115. Epub 2018 Oct 24. Proc Natl Acad Sci U S A. 2018. PMID: 30355767 Free PMC article.
The Ca(V)2.2 channel is composed of a pore-forming alpha(1) subunit (Ca(V)alpha(1)) that is engaged in protein-protein interactions with auxiliary alpha(2)/delta and beta subunits. The high-affinity Ca(V)2.2alpha(1)Ca(V)beta(3) protein-protein interact …
The Ca(V)2.2 channel is composed of a pore-forming alpha(1) subunit (Ca(V)alpha(1)) that is engaged in protein-protein interac …
Kolmogorov or Bolgiano-Obukhov scaling: Universal energy spectra in stably stratified turbulent fluids.
Basu A, Bhattacharjee JK. Basu A, et al. Phys Rev E. 2019 Sep;100(3-1):033117. doi: 10.1103/PhysRevE.100.033117. Phys Rev E. 2019. PMID: 31639948
For very low N or very high Re_{b} or F_{h}, and with l_{v}l_{h}, the typical horizontal length scale, buoyancy forces are irrelevant and hence, unsurprisingly, the kinetic energy spectra show the well-known K41 scaling in the inertial range. ...For intermediate ranges of …
For very low N or very high Re_{b} or F_{h}, and with l_{v}l_{h}, the typical horizontal length scale, buoyancy forces are irrelevant …
Optical propagation through non-overturning, undulating temperature sheets in the atmosphere.
Muschinski A. Muschinski A. J Opt Soc Am A Opt Image Sci Vis. 2016 Apr 1;33(4):793-800. doi: 10.1364/JOSAA.33.000793. J Opt Soc Am A Opt Image Sci Vis. 2016. PMID: 27140793
Here we present and discuss a model atmosphere characterized by randomly undulating, non-turbulent and non-overturning, quasi-horizontal refractive-index interfaces, or "sheets." We assume n(1)(x)=v[z-h(x,y)], where v(z) is a random function that has a 1D spectrum …
Here we present and discuss a model atmosphere characterized by randomly undulating, non-turbulent and non-overturning, quasi-horizontal ref …
Bromoenol lactone inhibits voltage-gated Ca2+ and transient receptor potential canonical channels.
Chakraborty S, Berwick ZC, Bartlett PJ, Kumar S, Thomas AP, Sturek M, Tune JD, Obukhov AG. Chakraborty S, et al. J Pharmacol Exp Ther. 2011 Nov;339(2):329-40. doi: 10.1124/jpet.111.183673. Epub 2011 Jul 27. J Pharmacol Exp Ther. 2011. PMID: 21795434 Free PMC article.
BEL completely inhibited not only thapsigargin- but also phenylephrine- and KCl-induced ring contractions, suggesting that Ca(V)1.2 and receptor-operated TRPC channels also may be sensitive to BEL. ...We found that low micromolar concentrations of BEL inhibited Ca(V …
BEL completely inhibited not only thapsigargin- but also phenylephrine- and KCl-induced ring contractions, suggesting that Ca(V)1.2 a …
Minimum turbulence assumptions and u* and L estimation for dispersion models during low-wind stable conditions.
Hanna SR, Chowdhury B. Hanna SR, et al. J Air Waste Manag Assoc. 2014 Mar;64(3):309-21. doi: 10.1080/10962247.2013.872709. J Air Waste Manag Assoc. 2014. PMID: 24701689
Observations show that as the mean wind speed approaches zero at night, there is always significant sigma(v) and sigma(w) over time periods of 15 to 60 min, while standard Monin-Obukhov Similarity Theory (MOST) predicts that sigma(v) and sigma(w) will approac …
Observations show that as the mean wind speed approaches zero at night, there is always significant sigma(v) and sigma(w) over time p …
New insights into the function and regulation of vitamin D target proteins.
Christakos S, Dhawan P, Peng X, Obukhov AG, Nowycky MC, Benn BS, Zhong Y, Liu Y, Shen Q. Christakos S, et al. J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):405-10. doi: 10.1016/j.jsbmb.2006.12.079. Epub 2006 Dec 22. J Steroid Biochem Mol Biol. 2007. PMID: 17257825 Free PMC article.
Co-immunoprecipitation and GST pull down assays indicate that calbindin-D(28k) interacts with the C-terminus of the L-type calcium channel alpha(1c) subunit (Ca(v)1.2). This is the first report of the binding of calbindin to a calcium channel and provides new insight conce …
Co-immunoprecipitation and GST pull down assays indicate that calbindin-D(28k) interacts with the C-terminus of the L-type calcium channel a …
Furanocoumarins are a novel class of modulators for the transient receptor potential vanilloid type 1 (TRPV1) channel.
Chen X, Sun W, Gianaris NG, Riley AM, Cummins TR, Fehrenbacher JC, Obukhov AG. Chen X, et al. J Biol Chem. 2014 Apr 4;289(14):9600-10. doi: 10.1074/jbc.M113.536862. Epub 2014 Feb 25. J Biol Chem. 2014. PMID: 24569998 Free PMC article.
Conversely, imperatorin sensitized TRPV1 to acid activation but did not affect the current amplitude and/or the activation-inactivation properties of Na(v)1.7, a channel important for transmission of nociceptive information. ...
Conversely, imperatorin sensitized TRPV1 to acid activation but did not affect the current amplitude and/or the activation-inactivation prop …
64 results