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Page 1
Effect of lipid-lowering therapies on C-reactive protein levels: a comprehensive meta-analysis of randomized controlled trials.
Xie S, Galimberti F, Olmastroni E, Luscher TF, Carugo S, Catapano AL, Casula M; META-LIPID Group. Xie S, et al. Cardiovasc Res. 2024 Mar 30;120(4):333-344. doi: 10.1093/cvr/cvae034. Cardiovasc Res. 2024. PMID: 38373008 Free PMC article.
Inclusion criteria were: (i) randomized controlled trials (RCTs) in human, Phase II, III, or IV; (ii) English language; (iii) comparing the effect of lipid-lowering drugs vs. placebo; (iv) reporting the effects on CRP levels; (v) with intervention duration of more than 3 w …
Inclusion criteria were: (i) randomized controlled trials (RCTs) in human, Phase II, III, or IV; (ii) English language; (iii) comparing the …
Adoptive transfer of CX3CR1 transduced-T regulatory cells improves homing to the atherosclerotic plaques and dampens atherosclerosis progression.
Bonacina F, Martini E, Svecla M, Nour J, Cremonesi M, Beretta G, Moregola A, Pellegatta F, Zampoleri V, Catapano AL, Kallikourdis M, Norata GD. Bonacina F, et al. Cardiovasc Res. 2021 Jul 27;117(9):2069-2082. doi: 10.1093/cvr/cvaa264. Cardiovasc Res. 2021. PMID: 32931583 Free article.
Treg overexpressing CX3CR1 were thus generated (CX3CR1+-Tregs) to drive Tregs selectively to the plaque. CX3CR1+-Tregs were injected (i.v.) in Ldlr -/- fed high-cholesterol diet (western type diet, WTD) for 8 weeks. ...
Treg overexpressing CX3CR1 were thus generated (CX3CR1+-Tregs) to drive Tregs selectively to the plaque. CX3CR1+-Tregs were injected (i.v …
The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism.
Demetz E, Schroll A, Auer K, Heim C, Patsch JR, Eller P, Theurl M, Theurl I, Theurl M, Seifert M, Lener D, Stanzl U, Haschka D, Asshoff M, Dichtl S, Nairz M, Huber E, Stadlinger M, Moschen AR, Li X, Pallweber P, Scharnagl H, Stojakovic T, März W, Kleber ME, Garlaschelli K, Uboldi P, Catapano AL, Stellaard F, Rudling M, Kuba K, Imai Y, Arita M, Schuetz JD, Pramstaller PP, Tietge UJF, Trauner M, Norata GD, Claudel T, Hicks AA, Weiss G, Tancevski I. Demetz E, et al. Cell Metab. 2014 Nov 4;20(5):787-798. doi: 10.1016/j.cmet.2014.09.004. Cell Metab. 2014. PMID: 25444678 Free PMC article.
Hypolipidaemic and anti-atherosclerotic effects of lupin proteins in a rabbit model.
Marchesi M, Parolini C, Diani E, Rigamonti E, Cornelli L, Arnoldi A, Sirtori CR, Chiesa G. Marchesi M, et al. Br J Nutr. 2008 Oct;100(4):707-10. doi: 10.1017/S000711450894215X. Br J Nutr. 2008. PMID: 18315889 Free article.
After surgery, animals were fed three different diets for 90 d, all with 1% cholesterol, 15% SFA and 20% protein; the protein source was casein (CAS), lupin proteins (LUP) or 50% CAS+50% LUP (CAS+LUP). Lower cholesterolaemia was detected in the LUP v. the CAS group at 60 a …
After surgery, animals were fed three different diets for 90 d, all with 1% cholesterol, 15% SFA and 20% protein; the protein source was cas …
Development of a model based on body composition to predict drug kinetics-1 evaluation in healthy volunteers.
Pazzucconi F, Ferrara S, Bondioli A, Zoppi F, Yeates R, De Rosa C, Mombelli G, Calabresi L, Sirtori CR. Pazzucconi F, et al. Pharmacol Res. 2004 Jul;50(1):99-104. doi: 10.1016/j.phrs.2003.12.009. Pharmacol Res. 2004. PMID: 15082035
Antipyrine, amlodipine, digoxin and tobramycin kinetics, liver microsomal activity enzyme (lidocaine/MEGX test), and appropriate clinical and laboratory tests were carried out. Major variables (V(d), AUC, t(1/2), C(max), Cl) for these drugs were calculated, and the …
Antipyrine, amlodipine, digoxin and tobramycin kinetics, liver microsomal activity enzyme (lidocaine/MEGX test), and appropriate clinical an …
15 results