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Page 1
Selexipag for the Treatment of Pulmonary Arterial Hypertension.
Sitbon O, Channick R, Chin KM, Frey A, Gaine S, Galiè N, Ghofrani HA, Hoeper MM, Lang IM, Preiss R, Rubin LJ, Di Scala L, Tapson V, Adzerikho I, Liu J, Moiseeva O, Zeng X, Simonneau G, McLaughlin VV; GRIPHON Investigators. Sitbon O, et al. N Engl J Med. 2015 Dec 24;373(26):2522-33. doi: 10.1056/NEJMoa1503184. N Engl J Med. 2015. PMID: 26699168 Free article. Clinical Trial.
Randomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care Workers.
Pittet LF, Messina NL, Orsini F, Moore CL, Abruzzo V, Barry S, Bonnici R, Bonten M, Campbell J, Croda J, Dalcolmo M, Gardiner K, Gell G, Germano S, Gomes-Silva A, Goodall C, Gwee A, Jamieson T, Jardim B, Kollmann TR, Lacerda MVG, Lee KJ, Lucas M, Lynn DJ, Manning L, Marshall HS, McDonald E, Munns CF, Nicholson S, O'Connell A, de Oliveira RD, Perlen S, Perrett KP, Prat-Aymerich C, Richmond PC, Rodriguez-Baño J, Dos Santos G, da Silva PV, Teo JW, Villanueva P, Warris A, Wood NJ, Davidson A, Curtis N; BRACE Trial Consortium Group. Pittet LF, et al. N Engl J Med. 2023 Apr 27;388(17):1582-1596. doi: 10.1056/NEJMoa2212616. N Engl J Med. 2023. PMID: 37099341 Free PMC article. Clinical Trial.
Advanced transcriptomic analysis reveals the role of efflux pumps and media composition in antibiotic responses of Pseudomonas aeruginosa.
Rajput A, Tsunemoto H, Sastry AV, Szubin R, Rychel K, Chauhan SM, Pogliano J, Palsson BO. Rajput A, et al. Nucleic Acids Res. 2022 Sep 23;50(17):9675-9688. doi: 10.1093/nar/gkac743. Nucleic Acids Res. 2022. PMID: 36095122 Free PMC article.
Our analysis revealed: (i) 116 iModulons, 81 of which show strong association with known regulators; (ii) novel roles of regulators in modulating antibiotics efflux pumps; (iii) substrate-efflux pump associations; (iv) differential iModulon activity in response to beta-lactam ant …
Our analysis revealed: (i) 116 iModulons, 81 of which show strong association with known regulators; (ii) novel roles of regulators in modul …
Machine learning from Pseudomonas aeruginosa transcriptomes identifies independently modulated sets of genes associated with known transcriptional regulators.
Rajput A, Tsunemoto H, Sastry AV, Szubin R, Rychel K, Sugie J, Pogliano J, Palsson BO. Rajput A, et al. Nucleic Acids Res. 2022 Apr 22;50(7):3658-3672. doi: 10.1093/nar/gkac187. Nucleic Acids Res. 2022. PMID: 35357493 Free PMC article.
We identified iModulons that (i) play an important role in defining the genomic boundaries of biosynthetic gene clusters (BGCs), (ii) show increased expression of the BGCs and associated secretion systems in nutrient conditions that are important in cystic fibrosis, (iii) show th …
We identified iModulons that (i) play an important role in defining the genomic boundaries of biosynthetic gene clusters (BGCs), (ii) show i …
Transcranial Doppler detection of venous-to-arterial circulation shunts: criteria for patent foramen ovale.
Sastry S, MacNab A, Daly K, Ray S, McCollum C. Sastry S, et al. J Clin Ultrasound. 2009 Jun;37(5):276-80. doi: 10.1002/jcu.20564. J Clin Ultrasound. 2009. PMID: 19353576
METHODS: Standardized TCD was performed 2 weeks before simultaneous TEE and TCD in 39 patients aged 15-39 following ischemic stroke (n = 33) or myocardial infarction (n = 6). V-aCS was investigated by contrast sonography. ...CONCLUSION: The standardized TCD p …
METHODS: Standardized TCD was performed 2 weeks before simultaneous TEE and TCD in 39 patients aged 15-39 following ischemic stroke (n …
S-adenosyl-L-methionine-mediated enzymatic methylations in the rat retinal membranes.
Sastry BV, Vidaver PS, Janson VE, Franks JJ. Sastry BV, et al. J Ocul Pharmacol. 1994 Spring;10(1):253-63. doi: 10.1089/jop.1994.10.253. J Ocul Pharmacol. 1994. PMID: 8207329
Methylation of PE in the rat retinal sonicates was assayed using 3H-SAM (2 microM) at 37 degrees C in Tris-glycylglycine buffer (50 mM, pH 8.0) and methylated phospholipids were extracted with chloroform/methanol/HCl (2/1/0.02, v/v) and separated by thin layer chrom …
Methylation of PE in the rat retinal sonicates was assayed using 3H-SAM (2 microM) at 37 degrees C in Tris-glycylglycine buffer (50 mM, pH 8 …
Young Adult Myocardial Infarction and Ischemic Stroke: the role of paradoxical embolism and thrombophilia (The YAMIS Study).
Sastry S, Riding G, Morris J, Taberner D, Cherry N, Heagerty A, McCollum C. Sastry S, et al. J Am Coll Cardiol. 2006 Aug 15;48(4):686-91. doi: 10.1016/j.jacc.2006.02.074. Epub 2006 Jul 25. J Am Coll Cardiol. 2006. PMID: 16904535 Free article.
The v-aCS were detected by transcranial Doppler after intravenous microbubble ultrasound contrast; "significant" v-aCS (> or =15 microbubble emboli) correlated with PFO on transesophageal echocardiography. ...Thrombophilia was not significantly associated with ei …
The v-aCS were detected by transcranial Doppler after intravenous microbubble ultrasound contrast; "significant" v-aCS (> o …
Topological phase transitions in two-dimensional bent-core liquid crystal models.
Latha BK, Dhara S, Sastry VSS. Latha BK, et al. Phys Rev E. 2021 Dec;104(6-1):064701. doi: 10.1103/PhysRevE.104.064701. Phys Rev E. 2021. PMID: 35030859
Two-dimensional liquid crystal (LC) models of interacting V-shaped bent-core molecules with two rigid rodlike identical segments connected at a fixed angle (teta=112^{}) are investigated. The model assigns equal biquadratic tensor coupling among constituents of the interac …
Two-dimensional liquid crystal (LC) models of interacting V-shaped bent-core molecules with two rigid rodlike identical segments conn …
Determination of Alkyl Methanesulfonates in Doxazosin Mesylate by Gas Chromatography-mass Spectrometer.
Sitaram C, Rupakula RB, Reddy BN, Sastry CS. Sitaram C, et al. Indian J Pharm Sci. 2011 Jan;73(1):107-10. doi: 10.4103/0250-474X.89769. Indian J Pharm Sci. 2011. PMID: 22131634 Free PMC article.
Acetonitrile, water and ammonia (90:9:1 v/v/v) mixture was used as diluent. Various factors involved in the gas chromatography-mass spectrometry method development are also presented. ...The limit of quantitation of methyl methanesulfonate, ethyl methanesulfo …
Acetonitrile, water and ammonia (90:9:1 v/v/v) mixture was used as diluent. Various factors involved in the gas chromat …
Comparison of hand hygiene compliance among healthcare workers in Intensive care units and wards of COVID-19: A large scale multicentric study in India.
Dhandapani S, Rajshekar D, Priyadarshi K, Krishnamoorthi S, Sundaramurthy R, Madigubba H, Sastry AS; Contributors of HHAC study group. Dhandapani S, et al. Am J Infect Control. 2023 Mar;51(3):304-312. doi: 10.1016/j.ajic.2022.09.028. Epub 2022 Oct 9. Am J Infect Control. 2023. PMID: 36223872 Free PMC article.
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