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Low but sustained coagulation activation ameliorates glucose-induced podocyte apoptosis: protective effect of factor V Leiden in diabetic nephropathy.
Wang H, Madhusudhan T, He T, Hummel B, Schmidt S, Vinnikov IA, Shahzad K, Kashif M, Muller-Krebs S, Schwenger V, Bierhaus A, Rudofsky G, Nawroth PP, Isermann B. Wang H, et al. Blood. 2011 May 12;117(19):5231-42. doi: 10.1182/blood-2010-10-314773. Epub 2011 Mar 9. Blood. 2011. PMID: 21389321 Free article.
Whereas it is generally perceived to be harmful, enhanced coagulation activation can also convey salutary effects. The high prevalence of the prothrombotic factor V Leiden (FVL) mutation in whites has been attributed to a positive selection pressure (eg, resulting from red …
Whereas it is generally perceived to be harmful, enhanced coagulation activation can also convey salutary effects. The high prevalence of th …
Podocyte Integrin-β3 and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy.
Madhusudhan T, Ghosh S, Wang H, Dong W, Gupta D, Elwakiel A, Stoyanov S, Al-Dabet MM, Krishnan S, Biemann R, Nazir S, Zimmermann S, Mathew A, Gadi I, Rana R, Zeng-Brouwers J, Moeller MJ, Schaefer L, Esmon CT, Kohli S, Reiser J, Rezaie AR, Ruf W, Isermann B. Madhusudhan T, et al. J Am Soc Nephrol. 2020 Aug;31(8):1762-1780. doi: 10.1681/ASN.2019111163. Epub 2020 Jul 24. J Am Soc Nephrol. 2020. PMID: 32709711 Free PMC article.
The interaction of aPC with integrin-alpha(v)beta(3) induces transient binding of integrin-beta(3) with G (alpha13) and controls PAR-dependent RhoA signaling in podocytes. ...These results identify integrin-alpha(v)beta(3) as an essential coreceptor for aPC that is …
The interaction of aPC with integrin-alpha(v)beta(3) induces transient binding of integrin-beta(3) with G (alpha13) and controls PAR- …
Alterations in Autophagy and Mammalian Target of Rapamycin (mTOR) Pathways Mediate Sarcopenia in Patients with Cirrhosis.
Anand A, Nambirajan A, Kumar V, Agarwal S, Sharma S, Mohta S, Gopi S, Kaushal K, Gunjan D, Singh N, Madhusudhan KS, Chauhan SS, Sharma MC, Bansal VK, Saraya A. Anand A, et al. J Clin Exp Hepatol. 2022 Mar-Apr;12(2):510-518. doi: 10.1016/j.jceh.2021.05.004. Epub 2021 May 21. J Clin Exp Hepatol. 2022. PMID: 35535114 Free PMC article.
Histological changes were assessed by hematoxylin and eosin staining and immunohistochemistry for phospho-FOXO3, phospho-AKT, phospho-mTOR, and apoptosis markers (annexin V and caspase 3). The messenger ribonucleic acid (mRNA) expressions for MSTN, FoxO3, markers of ubiqui …
Histological changes were assessed by hematoxylin and eosin staining and immunohistochemistry for phospho-FOXO3, phospho-AKT, phospho-mTOR, …
Serial Ultrasonographic-measurement of Gastric Residual Volume in Critically Ill Patients for Prediction of Gastric Tube Feed Intolerance.
Ankalagi B, Singh PM, Rewari V, Ramachandran R, Aggarwal R, Soni KD, Das D, Madhusudhan KS, Srivastava DN, Kaur M, Trikha A. Ankalagi B, et al. Indian J Crit Care Med. 2022 Sep;26(9):987-992. doi: 10.5005/jp-journals-10071-24296. Indian J Crit Care Med. 2022. PMID: 36213700 Free PMC article.
Gastric residual volume at the end of the fourth hour of feed, that is, GRV4 was the best predictor of feed intolerance with 99.3% area under the curve (AUROC), sensitivity of 99%, specificity of 99.3%, and 95% CI, 0.89-0.98 followed by GRV3, with AUROC of 96% and sensitivity and …
Gastric residual volume at the end of the fourth hour of feed, that is, GRV4 was the best predictor of feed intolerance with 99.3% area unde …
Restoration of Hand Function in Isolated Lower Brachial Plexus Injury with Brachioradialis to Flexor Pollicis Longus and Biceps to Flexor Digitorum Profundus Transfer.
Kummari VK, Bhardwaj P, Varadharajan V, Madhusudhan NC, Venkatramani H, Raja Sabapathy S. Kummari VK, et al. J Hand Surg Asian Pac Vol. 2022 Aug;27(4):599-606. doi: 10.1142/S2424835522500655. Epub 2022 Aug 11. J Hand Surg Asian Pac Vol. 2022. PMID: 35965380
Conclusions: BR to FPL for thumb flexion and biceps to FDP using fascia lata graft to restore finger flexion is simple and effective surgeries in patients with isolated lower BPI. Level of Evidence: Level V (Therapeutic)....
Conclusions: BR to FPL for thumb flexion and biceps to FDP using fascia lata graft to restore finger flexion is simple and effective surgeri …
Arthemeter-loaded lipid nanoparticles produced by modified thin-film hydration: Pharmacokinetics, toxicological and in vivo anti-malarial activity.
Aditya NP, Patankar S, Madhusudhan B, Murthy RS, Souto EB. Aditya NP, et al. Eur J Pharm Sci. 2010 Aug 11;40(5):448-55. doi: 10.1016/j.ejps.2010.05.007. Epub 2010 May 20. Eur J Pharm Sci. 2010. PMID: 20493255
Artemether-loaded lipid nanoparticles (ARM-LNP) composed of 5% (w/v) lipid mass were produced by a modified thin-film hydration method using glyceryl trimyristate (solid lipid) and soybean oil (as liquid lipid in a concentration ranging from 0 to 45% (w/v) with resp …
Artemether-loaded lipid nanoparticles (ARM-LNP) composed of 5% (w/v) lipid mass were produced by a modified thin-film hydration metho …
Analysis of trace metal concentrations in raw cow's milk from three dairy farms in North Gondar, Ethiopia: chemometric approach.
Akele ML, Abebe DZ, Alemu AK, Assefa AG, Madhusudhan A, de Oliveira RR. Akele ML, et al. Environ Monit Assess. 2017 Sep 11;189(10):499. doi: 10.1007/s10661-017-6203-0. Environ Monit Assess. 2017. PMID: 28895007
The samples were collected from the Nara-Awudarda, Tana-Abo, and Kosoye Amba-Rass sites in North Gondar, Ethiopia, preserved in a deep freezer (-20 C), and then digested by Kjeldahl apparatus with HNO(3)/H(2)O(2) (5:2; v/v) at 300 C for 2.5 h. The data were subject …
The samples were collected from the Nara-Awudarda, Tana-Abo, and Kosoye Amba-Rass sites in North Gondar, Ethiopia, preserved in a deep freez …
Development of bioconjugate from Streptomyces tyrosinase and gold nanoparticles for rapid detection of phenol constituents.
Zainab MB, Madhusudhan DN, Raghavendra H, Dastager SG, Dayanand A. Zainab MB, et al. Indian J Exp Biol. 2014 Nov;52(11):1071-81. Indian J Exp Biol. 2014. PMID: 25434102
Winery effluent has shown much higher content (0.98 O.D) of phenol constituents than paper and plastic effluents based on the intensity of color and U.V absorption spectra....
Winery effluent has shown much higher content (0.98 O.D) of phenol constituents than paper and plastic effluents based on the intensity of c …
13 results