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3,5,3'-Triiodo-L-Thyronine Regulates Actin Cytoskeleton Dynamic in The Differentiated PC-12 Cells during Hypoxia through An αvβ3 Integrin.
Barbakadze T, Kvergelidze E, Bátor J, Szeberényi J, Mikeladze D. Barbakadze T, et al. Cell J. 2023 Apr 1;25(4):247-254. doi: 10.22074/cellj.2022.557501.1059. Cell J. 2023. PMID: 37210645 Free PMC article.
Ischemia/hypoxia that induces rigidity of the actin filaments, which initiates neurodegeneration and reduces synaptic plasticity. We hypothesized that thyroid hormones via alpha-v-beta-3 (alphavbeta3) integrin could regulate the actin filament rearrangement during hypoxia …
Ischemia/hypoxia that induces rigidity of the actin filaments, which initiates neurodegeneration and reduces synaptic plasticity. We hypothe …
Ras proteins, nitrosylation and homocysteine metabolism.
Mikeladze D, Zhuravliova E, Barbakadze T. Mikeladze D, et al. Georgian Med News. 2008 Sep;(162):30-3. Georgian Med News. 2008. PMID: 18830027
PC12 pheochromocytoma cells expressing a dominant inhibitory mutant of Ha-ras (M-M17-26, PC12 pheochromocytoma cells expressing a mutant v-ras gene (MVR) and PC12 cells transfected with normal c-rasH (M-CR3B) has been used to investigate the role of nitrosylation and farne …
PC12 pheochromocytoma cells expressing a dominant inhibitory mutant of Ha-ras (M-M17-26, PC12 pheochromocytoma cells expressing a mutant …
Microcalorimetric study of iodized and noniodized cells and C-phycocyanin of Spirulina platensis.
Topchishvili LS, Barbakadze SI, Khizanishvili AI, Majagaladze GV, Monaselidze JR. Topchishvili LS, et al. Biomacromolecules. 2002 May-Jun;3(3):415-20. doi: 10.1021/bm0155928. Biomacromolecules. 2002. PMID: 12005509
It was shown that endotherm approximately 66 degrees C belongs to denaturation of C-phycocyanin which denaturates in solutions with Td = 64.2 degrees C, deltaHd = 34.7 +/- 2.1 J/g and for it deltaHd(cal)/deltaH(V.H) is equal to 10.8 +/- 1.2. The endotherms with Td equal to …
It was shown that endotherm approximately 66 degrees C belongs to denaturation of C-phycocyanin which denaturates in solutions with Td = 64. …
Microcalorimetric investigation of DNA, poly(dA)poly(dT) and poly[d(A-C)]poly[d(G-T)] melting in the presence of water soluble (meso tetra (4 N oxyethylpyridyl) porphyrin) and its Zn complex.
Monaselidze J, Majagaladze G, Barbakadze Sh, Khachidze D, Gorgoshidze M, Kalandadze Y, Haroutiunian S, Dalyan Y, Vardanyan V. Monaselidze J, et al. J Biomol Struct Dyn. 2008 Feb;25(4):419-24. doi: 10.1080/07391102.2008.10507190. J Biomol Struct Dyn. 2008. PMID: 18092836
Four-fold decrease of calf thymus DNA melting range width DeltaTm caused by increase of added ZnTOEpyp(4) concentration is explained by rapprochement of AT and GC pairs thermal stability, and it is in agreement with a well-known dependence, according to which DeltaT approximately …
Four-fold decrease of calf thymus DNA melting range width DeltaTm caused by increase of added ZnTOEpyp(4) concentration is explained by rapp …