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517 results

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Page 1
Showing results for vitro h. Rodrigues
Search for Vítor H. Rodrigues instead (2 results)
Extracellular Vesicles Regulate Biofilm Formation and Yeast-to-Hypha Differentiation in Candida albicans.
Honorato L, de Araujo JFD, Ellis CC, Piffer AC, Pereira Y, Frases S, de Sousa Araújo GR, Pontes B, Mendes MT, Pereira MD, Guimarães AJ, da Silva NM, Vargas G, Joffe L, Del Poeta M, Nosanchuk JD, Zamith-Miranda D, Dos Reis FCG, de Oliveira HC, Rodrigues ML, de Toledo Martins S, Alves LR, Almeida IC, Nimrichter L. Honorato L, et al. mBio. 2022 Jun 28;13(3):e0030122. doi: 10.1128/mbio.00301-22. Epub 2022 Apr 14. mBio. 2022. PMID: 35420476 Free PMC article.
C. albicans EVs from distinct strains inhibited yeast-to-hyphae differentiation with morphological changes occurring in less than 4 h. EVs from S. cerevisiae and H. capsulatum modestly reduced morphogenesis, and the effect was evident after 24 h of incubation …
C. albicans EVs from distinct strains inhibited yeast-to-hyphae differentiation with morphological changes occurring in less than 4 h …
In vitro assessment of hepatotoxicity by metabolomics: a review.
Cuykx M, Rodrigues RM, Laukens K, Vanhaecke T, Covaci A. Cuykx M, et al. Arch Toxicol. 2018 Oct;92(10):3007-3029. doi: 10.1007/s00204-018-2286-9. Epub 2018 Aug 25. Arch Toxicol. 2018. PMID: 30155722 Review.
Omics technologies, and in particular metabolomics, have received an increasing attention during the assessment of hepatotoxicity in vitro. However, at present, a consensus on good metabolomics practices has yet to be reached. ...The most frequently reported metabolites th …
Omics technologies, and in particular metabolomics, have received an increasing attention during the assessment of hepatotoxicity in vitr …
In silico, in vitro, and in vivo investigation of antioxidant potential and toxicity of ethyl ferulate.
Bomfim de Sá C, Brito Lira A, Filho AAO, de Oliveira KM, Rolim da Paz A, Castro de Morais M, de Sousa DP, Tafaela Dias G, Rodrigues Melo C, Pessôa HLF, Maria Bezerra Luna Lima C, de Fátima Formiga Melo Diniz M. Bomfim de Sá C, et al. Drug Chem Toxicol. 2022 Jul;45(4):1769-1779. doi: 10.1080/01480545.2021.1878207. Epub 2021 Feb 25. Drug Chem Toxicol. 2022. PMID: 33632037 Review.
PhD student Andressa Brito Lira participated in the critical review of the text for important intellectual content and assisted in the in vitro antioxidant activity and cytotoxicity tests. Kardilandia Mendes de Oliveira participated in acute oral toxicity tests evaluating …
PhD student Andressa Brito Lira participated in the critical review of the text for important intellectual content and assisted in the in …
Somatic gene mutations expose cytoplasmic DNA to co-opt the cGAS/STING/NLRP3 axis in myelodysplastic syndromes.
McLemore AF, Hou HA, Meyer BS, Lam NB, Ward GA, Aldrich AL, Rodrigues MA, Vedder A, Zhang L, Padron E, Vincelette ND, Sallman DA, Abdel-Wahab O, List AF, McGraw KL. McLemore AF, et al. JCI Insight. 2022 Aug 8;7(15):e159430. doi: 10.1172/jci.insight.159430. JCI Insight. 2022. PMID: 35788117 Free PMC article.
Mechanistically, caspase-1 degraded the master erythroid transcription factor, GATA binding protein 1, provoking anemia and myeloid lineage bias that was reversed by cGAS inhibition in vitro and in Tet2-/- hematopoietic stem and progenitor cell-transplanted mice. ...
Mechanistically, caspase-1 degraded the master erythroid transcription factor, GATA binding protein 1, provoking anemia and myeloid lineage …
Nuclear maturation kinetics and in vitro fertilization of immature bovine oocytes injected into pre-ovulatory follicles.
Simões LMS, Santos APC, Bottino MP, Lima EA, Fernandes UR, Orlandi RE, Rodrigues SAD, Caixeta FM, Alves NG, Souza JC, Quintão CCR, Camargo LSA, Dode MAN, Sales JNS. Simões LMS, et al. Theriogenology. 2021 May;166:90-96. doi: 10.1016/j.theriogenology.2020.12.021. Epub 2021 Jan 3. Theriogenology. 2021. PMID: 33711651
In Experiment 1, grade I, II and III cumulus-oocyte complexes (COCs) were randomly distributed to one of three Groups: Matvitro22 (COCs matured in vitro for 22 h), MatFol20 and MatFol28 (COCs matured in vivo after being injected into a pre-ovulatory follicle of prev …
In Experiment 1, grade I, II and III cumulus-oocyte complexes (COCs) were randomly distributed to one of three Groups: Matvitro22 (COCs matu …
Cynomolgus Monkey as an Emerging Animal Model to Study Drug Transporters: In Vitro, In Vivo, In Vitro-to-In Vivo Translation.
Shen H, Yang Z, Rodrigues AD. Shen H, et al. Drug Metab Dispos. 2022 Mar;50(3):299-319. doi: 10.1124/dmd.121.000695. Epub 2021 Dec 10. Drug Metab Dispos. 2022. PMID: 34893475 Review.
Burgeoning reports of data in the last few years necessitates a comprehensive review on the topic of drug transporters in cynomolgus monkeys that includes cell-based tools, sequence homology, tissue expression, in vitro studies, in vivo studies, and in vitro-to-in v …
Burgeoning reports of data in the last few years necessitates a comprehensive review on the topic of drug transporters in cynomolgus monkeys …
In vitro colonic fermentation and potential prebiotic properties of pre-digested jabuticaba (Myrciaria jaboticaba (Vell.) Berg) by-products.
Massa NML, de Oliveira SPA, Rodrigues NPA, Menezes FNDD, Dos Santos Lima M, Magnani M, de Souza EL. Massa NML, et al. Food Chem. 2022 Sep 15;388:133003. doi: 10.1016/j.foodchem.2022.133003. Epub 2022 Apr 21. Food Chem. 2022. PMID: 35462222 Free article.
Berg) by-products (JB) are rich sources of dietary fiber and phenolic compounds, which can be fermented by intestinal microbiota to promote health benefits. This study evaluated the effects of a 48 h-in vitro colonic fermentation of pre-digested JB on the contents o …
Berg) by-products (JB) are rich sources of dietary fiber and phenolic compounds, which can be fermented by intestinal microbiota to promote …
Cloning, Expression and Characterization of UDP-Glucose Dehydrogenases.
Couto MR, Rodrigues JL, Rodrigues LR. Couto MR, et al. Life (Basel). 2021 Nov 7;11(11):1201. doi: 10.3390/life11111201. Life (Basel). 2021. PMID: 34833077 Free PMC article.
Using S. cerevisiae as the expression host, the highest in vivo UDP-GlcA production was obtained for the strain CEN.PK2-1C expressing ZmUGD (17.9 M) or ChUGD (14.6 M). Regarding the in vitro assays, under the optimal conditions, E. coli cell extract containing LbjUGD was a …
Using S. cerevisiae as the expression host, the highest in vivo UDP-GlcA production was obtained for the strain CEN.PK2-1C expressing ZmUGD …
In vivo and in vitro short-term bisphenol A exposures disrupt testicular energy metabolism and negatively impact spermatogenesis in zebrafish.
Batista-Silva H, Rodrigues K, de Moura KRS, Elie N, Van Der Kraak G, Delalande C, Silva FRMB. Batista-Silva H, et al. Reprod Toxicol. 2022 Jan;107:10-21. doi: 10.1016/j.reprotox.2021.11.001. Epub 2021 Nov 11. Reprod Toxicol. 2022. PMID: 34775058
This study investigated the in vitro and short-term in vivo effects of Bisphenol A (BPA) on testicular energy metabolism and morphology in the zebrafish (Danio rerio). Testes were incubated in vitro for 1 h or fish were exposed in vivo to BPA in the tank wate …
This study investigated the in vitro and short-term in vivo effects of Bisphenol A (BPA) on testicular energy metabolism and morpholo …
A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans.
Caballero-Camino FJ, Rodrigues PM, Wångsell F, Agirre-Lizaso A, Olaizola P, Izquierdo-Sanchez L, Perugorria MJ, Bujanda L, Angelin B, Straniero S, Wallebäck A, Starke I, Gillberg PG, Strängberg E, Bonn B, Mattsson JP, Madsen MR, Hansen HH, Lindström E, Åkerblad P, Banales JM. Caballero-Camino FJ, et al. Hepatology. 2023 Sep 1;78(3):709-726. doi: 10.1097/HEP.0000000000000376. Epub 2023 Apr 1. Hepatology. 2023. PMID: 36999529 Free PMC article.
APPROACH AND RESULTS: A3907 was a potent and selective ASBT inhibitor in vitro. In rodents, orally administered A3907 distributed to the ASBT-expressing organs, that is, ileum, liver, and kidneys, and dose dependently increased fecal BA excretion. A3907 improved biochemica …
APPROACH AND RESULTS: A3907 was a potent and selective ASBT inhibitor in vitro. In rodents, orally administered A3907 distributed to …
517 results