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Page 1
Showing results for vitro antunes
Search for Vítor Antunes instead (2 results)
In vitro production of cat-restricted Toxoplasma pre-sexual stages.
Antunes AV, Shahinas M, Swale C, Farhat DC, Ramakrishnan C, Bruley C, Cannella D, Robert MG, Corrao C, Couté Y, Hehl AB, Bougdour A, Coppens I, Hakimi MA. Antunes AV, et al. Nature. 2024 Jan;625(7994):366-376. doi: 10.1038/s41586-023-06821-y. Epub 2023 Dec 13. Nature. 2024. PMID: 38093015 Free PMC article.
Their conditional and simultaneous depletion leads to a marked change in the transcriptional program, promoting a full transition from tachyzoites to merozoites. These in vitro-cultured pre-gametes have unique protein markers and undergo typical asexual endopolygenic divis …
Their conditional and simultaneous depletion leads to a marked change in the transcriptional program, promoting a full transition from tachy …
Establishment of mouse expanded potential stem cells.
Yang J, Ryan DJ, Wang W, Tsang JC, Lan G, Masaki H, Gao X, Antunes L, Yu Y, Zhu Z, Wang J, Kolodziejczyk AA, Campos LS, Wang C, Yang F, Zhong Z, Fu B, Eckersley-Maslin MA, Woods M, Tanaka Y, Chen X, Wilkinson AC, Bussell J, White J, Ramirez-Solis R, Reik W, Göttgens B, Teichmann SA, Tam PPL, Nakauchi H, Zou X, Lu L, Liu P. Yang J, et al. Nature. 2017 Oct 19;550(7676):393-397. doi: 10.1038/nature24052. Epub 2017 Oct 11. Nature. 2017. PMID: 29019987 Free PMC article.
Bona fide trophoblast stem cell lines and extra-embryonic endoderm stem cells can be directly derived from expanded potential stem cells in vitro. Molecular analyses of the epigenome and single-cell transcriptome reveal enrichment for blastomere-specific signature and a dy …
Bona fide trophoblast stem cell lines and extra-embryonic endoderm stem cells can be directly derived from expanded potential stem cells in …
Establishment of porcine and human expanded potential stem cells.
Gao X, Nowak-Imialek M, Chen X, Chen D, Herrmann D, Ruan D, Chen ACH, Eckersley-Maslin MA, Ahmad S, Lee YL, Kobayashi T, Ryan D, Zhong J, Zhu J, Wu J, Lan G, Petkov S, Yang J, Antunes L, Campos LS, Fu B, Wang S, Yong Y, Wang X, Xue SG, Ge L, Liu Z, Huang Y, Nie T, Li P, Wu D, Pei D, Zhang Y, Lu L, Yang F, Kimber SJ, Reik W, Zou X, Shang Z, Lai L, Surani A, Tam PPL, Ahmed A, Yeung WSB, Teichmann SA, Niemann H, Liu P. Gao X, et al. Nat Cell Biol. 2019 Jun;21(6):687-699. doi: 10.1038/s41556-019-0333-2. Epub 2019 Jun 3. Nat Cell Biol. 2019. PMID: 31160711 Free PMC article.
Here, we report the derivation of porcine EPSCs, which express key pluripotency genes, are genetically stable, permit genome editing, differentiate to derivatives of the three germ layers in chimeras and produce primordial germ cell-like cells in vitro. Under similar condi …
Here, we report the derivation of porcine EPSCs, which express key pluripotency genes, are genetically stable, permit genome editing, differ …
Generation and proof-of-concept for allogeneic CD123 CAR-Delta One T (DOT) cells in acute myeloid leukemia.
Sánchez Martínez D, Tirado N, Mensurado S, Martínez-Moreno A, Romecín P, Gutiérrez Agüera F, Correia DV, Silva-Santos B, Menéndez P. Sánchez Martínez D, et al. J Immunother Cancer. 2022 Sep;10(9):e005400. doi: 10.1136/jitc-2022-005400. J Immunother Cancer. 2022. PMID: 36162920 Free PMC article.
RESULTS: CD123CAR-DOTs showed vigorous, superior to control DOTs, cytotoxicity against AML cell lines and primary samples both in vitro and in vivo, even on tumor rechallenge. CONCLUSIONS: Our results provide the proof-of-concept for a DOT-based next-generation allogeneic …
RESULTS: CD123CAR-DOTs showed vigorous, superior to control DOTs, cytotoxicity against AML cell lines and primary samples both in vitro …
[Brucellosis].
Aleixo MJ, Ferreira ML, Antunes F. Aleixo MJ, et al. Acta Med Port. 1999 Dec;12(12):323-30. Acta Med Port. 1999. PMID: 10892434 Free article. Review. Portuguese.
Much is already known about the agent's molecular biology and in vitro behaviour, but, doubts persist about its in vivo activity, including in human infection. ...
Much is already known about the agent's molecular biology and in vitro behaviour, but, doubts persist about its in vivo activity, inc …
In Vitro Cancer Models: A Closer Look at Limitations on Translation.
Antunes N, Kundu B, Kundu SC, Reis RL, Correlo V. Antunes N, et al. Bioengineering (Basel). 2022 Apr 7;9(4):166. doi: 10.3390/bioengineering9040166. Bioengineering (Basel). 2022. PMID: 35447726 Free PMC article. Review.
In vitro cancer models are envisioned as high-throughput screening platforms for potential new therapeutic discovery and/or validation. ...The state of the art of in vitro cancer models is discussed first, followed by identifying the limitations of bench-to-bedside …
In vitro cancer models are envisioned as high-throughput screening platforms for potential new therapeutic discovery and/or validatio …
In vitro production of cat-restricted Toxoplasma pre-sexual stages by epigenetic reprogramming.
Antunes AV, Shahinas M, Swale C, Farhat DC, Ramakrishnan C, Bruley C, Cannella D, Corrao C, Cout Y, Hehl AB, Bougdour A, Coppens I, Hakimi MA. Antunes AV, et al. bioRxiv [Preprint]. 2023 Jan 17:2023.01.16.524187. doi: 10.1101/2023.01.16.524187. bioRxiv. 2023. PMID: 36711883 Free PMC article. Updated. Preprint.
Their conditional and simultaneous depletion leads to a drastic change in the transcriptional program, promoting a complete transition from tachyzoites to merozoites. Pre-gametes produced in vitro under these conditions are characterized by specific protein markers and und …
Their conditional and simultaneous depletion leads to a drastic change in the transcriptional program, promoting a complete transition from …
36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016.
Bateman RM, Sharpe MD, Jagger JE, Ellis CG, Solé-Violán J, López-Rodríguez M, Herrera-Ramos E, Ruíz-Hernández J, Borderías L, Horcajada J, González-Quevedo N, Rajas O, Briones M, Rodríguez de Castro F, Rodríguez Gallego C, Esen F, Orhun G, Ergin Ozcan P, Senturk E, Ugur Yilmaz C, Orhan N, Arican N, Kaya M, Kucukerden M, Giris M, Akcan U, Bilgic Gazioglu S, Tuzun E, Riff R, Naamani O, Douvdevani A, Takegawa R, Yoshida H, Hirose T, Yamamoto N, Hagiya H, Ojima M, Akeda Y, Tasaki O, Tomono K, Shimazu T, Ono S, Kubo T, Suda S, Ueno T, Ikeda T, Hirose T, Ogura H, Takahashi H, Ojima M, Kang J, Nakamura Y, Kojima T, Shimazu T, Ikeda T, Suda S, Izutani Y, Ueno T, Ono S, Taniguchi T, O M, Dinter C, Lotz J, Eilers B, Wissmann C, Lott R, Meili MM, Schuetz PS, Hawa H, Sharshir M, Aburageila M, Salahuddin N, Chantziara V, Georgiou S, Tsimogianni A, Alexandropoulos P, Vassi A, Lagiou F, Valta M, Micha G, Chinou E, Michaloudis G, Kodaira A, Ikeda T, Ono S, Ueno T, Suda S, Izutani Y, Imaizumi H, De la Torre-Prados MV, Garcia-De la Torre A, Enguix-Armada A, Puerto-Morlan A, Perez-Valero V, Garcia-Alcantara A, Bolton N, Dudziak J, Bonney S, Tridente A, Nee P, Nicolaes G, Wiewel M, Schultz M, Wildhag… See abstract for full author list ➔ Bateman RM, et al. Crit Care. 2016 Apr 20;20(Suppl 2):94. doi: 10.1186/s13054-016-1208-6. Crit Care. 2016. PMID: 27885969 Free PMC article.
Kleinsasser P114 - Filtering of red blood cells reduces the inflammatory response of pulmonary cells in an in vitro model of mechanical ventilation M. R. Witrz, J. F. Buchner-Doeven, A. ...Hoermann P192 - Removal of bilirubin with a new adsorbent system: in vitro ki …
Kleinsasser P114 - Filtering of red blood cells reduces the inflammatory response of pulmonary cells in an in vitro model of mechanic …
Nanoparticle-Based Treatment in Glioblastoma.
Roque D, Cruz N, Ferreira HA, Reis CP, Matela N, Herculano-Carvalho M, Cascão R, Faria CC. Roque D, et al. J Pers Med. 2023 Aug 29;13(9):1328. doi: 10.3390/jpm13091328. J Pers Med. 2023. PMID: 37763096 Free PMC article. Review.
Various methods of drug delivery that pass through the BBB, such as the stereotactic injection of nanoparticles, are being actively tested in vitro and in vivo in animal models. A significant variety of pre-clinical studies with polymeric nanoparticles for the treatment of …
Various methods of drug delivery that pass through the BBB, such as the stereotactic injection of nanoparticles, are being actively tested i …
CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia.
Cardoso BA, Duque M, Gírio A, Fragoso R, Oliveira ML, Allen JR, Martins LR, Correia NC, Silveira AB, Veloso A, Kimura S, Demoen L, Matthijssens F, Jeha S, Cheng C, Pui CH, Grosso AR, Neto JL, De Almeida SF, Van Vlieberghe P, Mullighan CG, Yunes JA, Langenau DM, Pflumio F, Barata JT. Cardoso BA, et al. Haematologica. 2023 Dec 7. doi: 10.3324/haematol.2023.282854. Online ahead of print. Haematologica. 2023. PMID: 38058200 Free article.
In agreement, overexpression of CASZ1b in both Ba/F3 and T-ALL cells leads to the activation of PI3K signaling pathway, which is required for CASZ1b-mediated transformation of Ba/F3 cells in vitro and malignant expansion in vivo. We further demonstrate that CASZ1b cooperat …
In agreement, overexpression of CASZ1b in both Ba/F3 and T-ALL cells leads to the activation of PI3K signaling pathway, which is required fo …
508 results