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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
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1984 2
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1986 2
1987 2
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1989 4
1990 7
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1993 2
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1997 3
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1999 3
2000 8
2001 5
2002 7
2003 10
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2024 54

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2,490 results

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The following term was not found in PubMed: Barokah
Page 1
UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy.
Smith T, Heger A, Sudbery I. Smith T, et al. Genome Res. 2017 Mar;27(3):491-499. doi: 10.1101/gr.209601.116. Epub 2017 Jan 18. Genome Res. 2017. PMID: 28100584 Free PMC article.
However, bioinformatic methods to leverage the information from UMIs have yet to be formalized. In particular, sequencing errors in the UMI sequence are often ignored or else resolved in an ad hoc manner. We show that errors in the UMI sequence are common and introd …
However, bioinformatic methods to leverage the information from UMIs have yet to be formalized. In particular, sequencing errors in the U …
High-accuracy long-read amplicon sequences using unique molecular identifiers with Nanopore or PacBio sequencing.
Karst SM, Ziels RM, Kirkegaard RH, Sørensen EA, McDonald D, Zhu Q, Knight R, Albertsen M. Karst SM, et al. Nat Methods. 2021 Feb;18(2):165-169. doi: 10.1038/s41592-020-01041-y. Epub 2021 Jan 11. Nat Methods. 2021. PMID: 33432244
We applied our approach to sequence ribosomal RNA operon amplicons (~4,500 bp) and genomic sequences (>10,000 bp) of reference microbial communities in which we observed a chimera rate <0.02%. To reach a mean UMI consensus error rate <0.01%, a UMI read cove …
We applied our approach to sequence ribosomal RNA operon amplicons (~4,500 bp) and genomic sequences (>10,000 bp) of reference microbial …
Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer's disease mouse model.
Cen X, Chen Y, Xu X, Wu R, He F, Zhao Q, Sun Q, Yi C, Wu J, Najafov A, Xia H. Cen X, et al. Nat Commun. 2020 Nov 12;11(1):5731. doi: 10.1038/s41467-020-19547-6. Nat Commun. 2020. PMID: 33184293 Free PMC article.
Here, we screen a library of 2024 FDA-approved drugs or drug candidates, revealing UMI-77 as an unexpected mitophagy activator. UMI-77 is an established BH3-mimetic for MCL-1 and was developed to induce apoptosis in cancer cells. ...Finally, we found that UMI …
Here, we screen a library of 2024 FDA-approved drugs or drug candidates, revealing UMI-77 as an unexpected mitophagy activator. UM …
UMI-Varcal: A Low-Frequency Variant Caller for UMI-Tagged Paired-End Sequencing Data.
Sater V, Viailly PJ, Lecroq T, Prieur-Gaston É, Bohers É, Viennot M, Ruminy P, Dauchel H, Vera P, Jardin F. Sater V, et al. Methods Mol Biol. 2022;2493:235-245. doi: 10.1007/978-1-0716-2293-3_14. Methods Mol Biol. 2022. PMID: 35751818
Filtering these artifacts can be a rather difficult task especially when the experiments are designed to look for very low frequency variants. Recently, adding unique molecular barcodes called UMI (Unique Molecular Identifier) to the DNA fragments appears to be a very effe …
Filtering these artifacts can be a rather difficult task especially when the experiments are designed to look for very low frequency variant …
Fasting-mimicking diet synergizes with ferroptosis against quiescent, chemotherapy-resistant cells.
Liu X, Peng S, Tang G, Xu G, Xie Y, Shen D, Zhu M, Huang Y, Wang X, Yu H, Huang M, Luo Y. Liu X, et al. EBioMedicine. 2023 Apr;90:104496. doi: 10.1016/j.ebiom.2023.104496. Epub 2023 Feb 28. EBioMedicine. 2023. PMID: 36863257 Free PMC article.
BACKGROUND: More than ten randomized clinical trials are being tested to evaluate the efficacy, effectiveness and safety of a fasting-mimicking diet (FMD) combined with different antitumor agents. METHODS: UMI-mRNA sequencing, Cell-cycle analysis, Label retention, metabolo …
BACKGROUND: More than ten randomized clinical trials are being tested to evaluate the efficacy, effectiveness and safety of a fasting-mimick …
Demystifying "drop-outs" in single-cell UMI data.
Kim TH, Zhou X, Chen M. Kim TH, et al. Genome Biol. 2020 Aug 6;21(1):196. doi: 10.1186/s13059-020-02096-y. Genome Biol. 2020. PMID: 32762710 Free PMC article.
Many existing pipelines for scRNA-seq data apply pre-processing steps such as normalization or imputation to account for excessive zeros or "drop-outs." Here, we extensively analyze diverse UMI data sets to show that clustering should be the foremost step of the workflow. …
Many existing pipelines for scRNA-seq data apply pre-processing steps such as normalization or imputation to account for excessive zeros or …
Alignment-free clustering of UMI tagged DNA molecules.
Orabi B, Erhan E, McConeghy B, Volik SV, Le Bihan S, Bell R, Collins CC, Chauve C, Hach F. Orabi B, et al. Bioinformatics. 2019 Jun 1;35(11):1829-1836. doi: 10.1093/bioinformatics/bty888. Bioinformatics. 2019. PMID: 30351359
Barcode tagging of DNA molecules with unique molecular identifiers (UMI) attempts to mitigate sequencing errors; UMI tagged molecules are polymerase chain reaction (PCR) amplified, and the PCR copies of UMI tagged molecules are sequenced independently. ...Cal …
Barcode tagging of DNA molecules with unique molecular identifiers (UMI) attempts to mitigate sequencing errors; UMI tagged mo …
UMI-count modeling and differential expression analysis for single-cell RNA sequencing.
Chen W, Li Y, Easton J, Finkelstein D, Wu G, Chen X. Chen W, et al. Genome Biol. 2018 May 31;19(1):70. doi: 10.1186/s13059-018-1438-9. Genome Biol. 2018. PMID: 29855333 Free PMC article.
Read counting and unique molecular identifier (UMI) counting are the principal gene expression quantification schemes used in single-cell RNA-sequencing (scRNA-seq) analysis. ...Our results show that this properly controls the FDR and achieves better power for UMI c …
Read counting and unique molecular identifier (UMI) counting are the principal gene expression quantification schemes used in single- …
2,490 results