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Page 1
Small Molecule Inhibitors for Unc-51-like Autophagy-Activating Kinase Targeting Autophagy in Cancer.
Int J Mol Sci. 2023 Jan 4;24(2):953. doi: 10.3390/ijms24020953.
Int J Mol Sci. 2023.
PMID: 36674464
Free PMC article.
Review.
Synthesis and activity of N-(5-hydroxy-3,4,6-trimethylpyridin-2-yl)acetamide analogues as anticolitis agents via dual inhibition of TNF-α- and IL-6-induced cell adhesions.
Karmacharya U, Regmi SC, Awasthi BP, Chaudhary P, Kim YE, Lee IH, Nam TG, Kim JA, Jeong BS.
Karmacharya U, et al.
Bioorg Med Chem Lett. 2021 Jul 1;43:128059. doi: 10.1016/j.bmcl.2021.128059. Epub 2021 Apr 23.
Bioorg Med Chem Lett. 2021.
PMID: 33895277
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Synthesis and anticancer evaluation of 6-azacyclonol-2,4,6-trimethylpyridin-3-ol derivatives: M3 muscarinic acetylcholine receptor-mediated anticancer activity of a cyclohexyl derivative in androgen-refractory prostate cancer.
Karmacharya U, Chaudhary P, Lim D, Dahal S, Awasthi BP, Park HD, Kim JA, Jeong BS.
Karmacharya U, et al.
Bioorg Chem. 2021 May;110:104805. doi: 10.1016/j.bioorg.2021.104805. Epub 2021 Mar 6.
Bioorg Chem. 2021.
PMID: 33725508
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Novel Pyridine Bioisostere of Cabozantinib as a Potent c-Met Kinase Inhibitor: Synthesis and Anti-Tumor Activity against Hepatocellular Carcinoma.
Karmacharya U, Guragain D, Chaudhary P, Jee JG, Kim JA, Jeong BS.
Karmacharya U, et al.
Int J Mol Sci. 2021 Sep 7;22(18):9685. doi: 10.3390/ijms22189685.
Int J Mol Sci. 2021.
PMID: 34575841
Free PMC article.
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In vitro and in vivo inhibitory activity of 6-amino-2,4,5-trimethylpyridin-3-ols against inflammatory bowel disease.
Banskota S, Kang HE, Kim DG, Park SW, Jang H, Karmacharya U, Jeong BS, Kim JA, Nam TG.
Banskota S, et al. Among authors: karmacharya u.
Bioorg Med Chem Lett. 2016 Oct 1;26(19):4587-4591. doi: 10.1016/j.bmcl.2016.08.075. Epub 2016 Aug 24.
Bioorg Med Chem Lett. 2016.
PMID: 27597248
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Investigating the anti-cancer potential of pyrimethamine analogues through a modern chemical biology lens.
Brown JI, Persaud R, Iliev P, Karmacharya U, Attarha S, Sahile H, Olsen JE, Hanke D, Idowu T, Frank DA, Frankel A, Williams KC, Page BDG.
Brown JI, et al. Among authors: karmacharya u.
Eur J Med Chem. 2024 Jan 15;264:115971. doi: 10.1016/j.ejmech.2023.115971. Epub 2023 Nov 29.
Eur J Med Chem. 2024.
PMID: 38071795
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Potent Inhibitory Effect of BJ-3105, a 6-Alkoxypyridin-3-ol Derivative, on Murine Colitis Is Mediated by Activating AMPK and Inhibiting NOX.
Gurung P, Dahal S, Chaudhary P, Guragain D, Karmacharya U, Kim JA, Jeong BS.
Gurung P, et al. Among authors: karmacharya u.
Int J Mol Sci. 2020 Apr 29;21(9):3145. doi: 10.3390/ijms21093145.
Int J Mol Sci. 2020.
PMID: 32365634
Free PMC article.
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