Diffuse alveolar hemorrhage following intravenous thrombolytic treatment in acute ischemic stroke: a case series

Neurol Sci. 2020 Jan;41(1):233-237. doi: 10.1007/s10072-019-03997-y. Epub 2019 Jul 6.

Abstract

Diffuse alveolar hemorrhage (DAH) following fibrinolytic therapy is a rare but a life-threatening complication. In acute ischemic stroke (AIS), DAH as a complication was not reported following intravenous thrombolytic therapy (ITT). The demographic, clinical, radiologic, and prognostic data of 4 patients with AIS who developed DAH after ITT are presented in this case series, along with a literature review.

Keywords: Acute ischemic stroke; Diffuse alveolar hemorrhage; Intravenous thrombolytic treatment; Prognosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Brain Ischemia / diagnostic imaging*
  • Brain Ischemia / drug therapy
  • Female
  • Hemorrhage / chemically induced*
  • Hemorrhage / diagnostic imaging*
  • Humans
  • Infusions, Intravenous
  • Lung / diagnostic imaging*
  • Stroke / diagnostic imaging*
  • Stroke / drug therapy
  • Thrombolytic Therapy / adverse effects*