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Piperidine CD4-mimetic compounds expose vulnerable Env epitopes sensitizing HIV-1-infected cells to ADCC.
Ding S, Tolbert WD, Zhu H, Lee D, Higgins T, Zhao X, Nguyen D, Sherburn R, Richard J, Lepage GG, Medjahed H, Mohammadi M, Abrams C, Pazgier M, Smith AB 3rd, Finzi A. Ding S, et al. Among authors: higgins t. bioRxiv [Preprint]. 2023 Mar 24:2023.03.23.533923. doi: 10.1101/2023.03.23.533923. bioRxiv. 2023. PMID: 36993184 Free PMC article. Updated. Preprint.
A 3-(4-nitronaphthen-1-yl) amino-benzoate analog as a bifunctional AKR1C3 inhibitor and AR antagonist: Head to head comparison with other advanced AKR1C3 targeted therapeutics.
Wangtrakuldee P, Adeniji AO, Zang T, Duan L, Khatri B, Twenter BM, Estrada MA, Higgins TF, Winkler JD, Penning TM. Wangtrakuldee P, et al. Among authors: higgins tf. J Steroid Biochem Mol Biol. 2019 Sep;192:105283. doi: 10.1016/j.jsbmb.2019.01.001. Epub 2019 Jan 11. J Steroid Biochem Mol Biol. 2019. PMID: 30641225 Free PMC article.