Posttranslational modification of microtubules by the MATCAP detyrosinase.
Landskron L, Bak J, Adamopoulos A, Kaplani K, Moraiti M, van den Hengel LG, Song JY, Bleijerveld OB, Nieuwenhuis J, Heidebrecht T, Henneman L, Moutin MJ, Barisic M, Taraviras S, Perrakis A, Brummelkamp TR.
Landskron L, et al.
Science. 2022 May 20;376(6595):eabn6020. doi: 10.1126/science.abn6020. Epub 2022 May 20.
Science. 2022.
PMID: 35482892
The detyrosination-tyrosination cycle involves the removal and religation of the C-terminal tyrosine of alpha-tubulin and is implicated in cognitive, cardiac, and mitotic defects. ...
The detyrosination-tyrosination cycle involves the removal and religation of the C-terminal tyrosine of alpha-tubulin and is implicat …