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Page 1
Functional and morphological renal changes in a Göttingen Minipig model of obesity-related and diabetic nephropathy.
Christoffersen BØ, Kristensen CA, Lindgaard R, Kirk RK, Viuff BM, Kvist PH, Pedersen HD, Ludvigsen TP, Skovgaard T, Fels JJ, Martinussen T, Christiansen LB, Cirera S, Olsen LH. Christoffersen BØ, et al. Among authors: ludvigsen tp. Sci Rep. 2023 Apr 12;13(1):6017. doi: 10.1038/s41598-023-32674-6. Sci Rep. 2023. PMID: 37045950 Free PMC article.
Optimization of pig models for translation of subcutaneous pharmacokinetics of therapeutic proteins: Liraglutide, insulin aspart and insulin detemir.
Pedersen KM, Gradel AKJ, Ludvigsen TP, Christoffersen BØ, Fuglsang-Damgaard CA, Bendtsen KM, Madsen SH, Manfé V, Refsgaard HHF. Pedersen KM, et al. Among authors: ludvigsen tp. Transl Res. 2022 Jan;239:71-84. doi: 10.1016/j.trsl.2021.08.005. Epub 2021 Aug 21. Transl Res. 2022. PMID: 34428585 Free article.
Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected.
Christiansen LB, Dohlmann TL, Ludvigsen TP, Parfieniuk E, Ciborowski M, Szczerbinski L, Kretowski A, Desler C, Tiano L, Orlando P, Martinussen T, Olsen LH, Larsen S. Christiansen LB, et al. Among authors: ludvigsen tp. Sci Rep. 2021 Jan 26;11(1):2167. doi: 10.1038/s41598-021-81846-9. Sci Rep. 2021. PMID: 33500513 Free PMC article.
The expression signatures in liver and adipose tissue from obese Göttingen Minipigs reveal a predisposition for healthy fat accumulation.
Cirera S, Taşöz E, Juul Jacobsen M, Schumacher-Petersen C, Østergaard Christoffersen B, Kaae Kirk R, Pagh Ludvigsen T, Hvid H, Duelund Pedersen H, Høier Olsen L, Fredholm M. Cirera S, et al. Among authors: pagh ludvigsen t. Nutr Diabetes. 2020 Mar 23;10(1):9. doi: 10.1038/s41387-020-0112-y. Nutr Diabetes. 2020. PMID: 32205840 Free PMC article.
Dietary normalization from a fat, fructose and cholesterol-rich diet to chow limits the amount of myocardial collagen in a Göttingen Minipig model of obesity.
Andreasen LJ, Krog S, Ludvigsen TP, Nielsen OL, Møller JE, Christoffersen BØ, Pedersen HD, Olsen LH. Andreasen LJ, et al. Among authors: ludvigsen tp. Nutr Metab (Lond). 2018 Sep 25;15:64. doi: 10.1186/s12986-018-0303-x. eCollection 2018. Nutr Metab (Lond). 2018. PMID: 30263039 Free PMC article.
Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals.
Ludvigsen TP, Kirk RK, Christoffersen BØ, Pedersen HD, Martinussen T, Kildegaard J, Heegaard PM, Lykkesfeldt J, Olsen LH. Ludvigsen TP, et al. J Transl Med. 2015 Sep 22;13:312. doi: 10.1186/s12967-015-0670-2. J Transl Med. 2015. PMID: 26394837 Free PMC article.