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2015 1
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2022 3
2023 5
2024 0

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Page 1
GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models.
Gorgogietas V, Rajaei B, Heeyoung C, Santacreu BJ, Marín-Cañas S, Salpea P, Sawatani T, Musuaya A, Arroyo MN, Moreno-Castro C, Benabdallah K, Demarez C, Toivonen S, Cosentino C, Pachera N, Lytrivi M, Cai Y, Carnel L, Brown C, Urano F, Marchetti P, Gilon P, Eizirik DL, Cnop M, Igoillo-Esteve M. Gorgogietas V, et al. Among authors: sawatani t. Diabetologia. 2023 Jul;66(7):1306-1321. doi: 10.1007/s00125-023-05905-8. Epub 2023 Mar 30. Diabetologia. 2023. PMID: 36995380 Free PMC article.
EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion.
Blanchi B, Taurand M, Colace C, Thomaidou S, Audeoud C, Fantuzzi F, Sawatani T, Gheibi S, Sabadell-Basallote J, Boot FWJ, Chantier T, Piet A, Cavanihac C, Pilette M, Balguerie A, Olleik H, Carlotti F, Ejarque M, Fex M, Mulder H, Cnop M, Eizirik DL, Jouannot O, Gaffuri AL, Czernichow P, Zaldumbide A, Scharfmann R, Ravassard P. Blanchi B, et al. Among authors: sawatani t. Mol Metab. 2023 Oct;76:101772. doi: 10.1016/j.molmet.2023.101772. Epub 2023 Jul 11. Mol Metab. 2023. PMID: 37442376 Free PMC article.
Inferring regulators of cell identity in the human adult pancreas.
Vanheer L, Fantuzzi F, To SK, Schiavo A, Van Haele M, Ostyn T, Haesen T, Yi X, Janiszewski A, Chappell J, Rihoux A, Sawatani T, Roskams T, Pattou F, Kerr-Conte J, Cnop M, Pasque V. Vanheer L, et al. Among authors: sawatani t. NAR Genom Bioinform. 2023 Jul 10;5(3):lqad068. doi: 10.1093/nargab/lqad068. eCollection 2023 Sep. NAR Genom Bioinform. 2023. PMID: 37435358 Free PMC article.
LncRNA ARGI Contributes to Virus-Induced Pancreatic β Cell Inflammation Through Transcriptional Activation of IFN-Stimulated Genes.
González-Moro I, Garcia-Etxebarria K, Mendoza LM, Fernández-Jiménez N, Mentxaka J, Olazagoitia-Garmendia A, Arroyo MN, Sawatani T, Moreno-Castro C, Vinci C, Op de Beek A, Cnop M, Igoillo-Esteve M, Santin I. González-Moro I, et al. Among authors: sawatani t. Adv Sci (Weinh). 2023 Sep;10(25):e2300063. doi: 10.1002/advs.202300063. Epub 2023 Jun 29. Adv Sci (Weinh). 2023. PMID: 37382191 Free PMC article.
YIPF5 mutations cause neonatal diabetes and microcephaly through endoplasmic reticulum stress.
De Franco E, Lytrivi M, Ibrahim H, Montaser H, Wakeling MN, Fantuzzi F, Patel K, Demarez C, Cai Y, Igoillo-Esteve M, Cosentino C, Lithovius V, Vihinen H, Jokitalo E, Laver TW, Johnson MB, Sawatani T, Shakeri H, Pachera N, Haliloglu B, Ozbek MN, Unal E, Yıldırım R, Godbole T, Yildiz M, Aydin B, Bilheu A, Suzuki I, Flanagan SE, Vanderhaeghen P, Senée V, Julier C, Marchetti P, Eizirik DL, Ellard S, Saarimäki-Vire J, Otonkoski T, Cnop M, Hattersley AT. De Franco E, et al. Among authors: sawatani t. J Clin Invest. 2020 Dec 1;130(12):6338-6353. doi: 10.1172/JCI141455. J Clin Invest. 2020. PMID: 33164986 Free PMC article.
The sialidase inhibitor 2,3-dehydro-2-deoxy-N-acetylneuraminic acid is a glucose-dependent potentiator of insulin secretion.
Minami A, Fujita Y, Shimba S, Shiratori M, Kaneko YK, Sawatani T, Otsubo T, Ikeda K, Kanazawa H, Mikami Y, Sekita R, Kurebayashi Y, Takahashi T, Miyagi T, Ishikawa T, Suzuki T. Minami A, et al. Among authors: sawatani t. Sci Rep. 2020 Mar 23;10(1):5198. doi: 10.1038/s41598-020-62203-8. Sci Rep. 2020. PMID: 32251344 Free PMC article.
In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo.
Fantuzzi F, Toivonen S, Schiavo AA, Chae H, Tariq M, Sawatani T, Pachera N, Cai Y, Vinci C, Virgilio E, Ladriere L, Suleiman M, Marchetti P, Jonas JC, Gilon P, Eizirik DL, Igoillo-Esteve M, Cnop M. Fantuzzi F, et al. Among authors: sawatani t. Front Cell Dev Biol. 2022 Aug 17;10:967765. doi: 10.3389/fcell.2022.967765. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36060810 Free PMC article.
15 results