A DNA-gold nanoparticle hybrid hydrogel network prepared by enzymatic reaction

Yuka Eguchi; Tomoharu Kato; Tsutomu Tanaka; Tatsuo Maruyama

doi:10.1039/c7cc02435e

A DNA-gold nanoparticle hybrid hydrogel network prepared by enzymatic reaction

Chem Commun (Camb). 2017 May 30;53(43):5802-5805. doi: 10.1039/c7cc02435e.

Authors

Yuka Eguchi¹, Tomoharu Kato, Tsutomu Tanaka, Tatsuo Maruyama

Affiliation

¹ Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodai, Nada-ku, Kobe 657-8501, Japan. tmarutcm@crystal.kobe-u.ac.jp.

PMID: 28451679
DOI: 10.1039/c7cc02435e

Abstract

We report a DNA-gold nanoparticle (AuNP) hybrid hydrogel in which the AuNPs crosslink enzymatically synthesized DNA to form a gel network. PCR-elongated DNA and AuNPs act as a one-dimensional polymer and cross-linkers, respectively. The DNA-AuNP hydrogel has the functional properties of both long DNA and the AuNPs.

MeSH terms

DNA / chemistry*
DNA / genetics
DNA / metabolism*
Deoxyribonuclease EcoRI / metabolism*
Deoxyribonucleases, Type II Site-Specific / metabolism*
Gold / chemistry*
Gold / metabolism
Hydrogels / chemistry
Hydrogels / metabolism*
Metal Nanoparticles / chemistry*
Polymerase Chain Reaction

Substances

Hydrogels
Gold
DNA
Deoxyribonuclease EcoRI
Deoxyribonucleases, Type II Site-Specific
YGGCCR-specific type II deoxyribonucleases