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The following term was not found in PubMed: chandarasupsang
Page 1
Showing results for tirap chandarasupsang
Your search for Tirapot Chandarasupsang retrieved no results
TIRAP in the Mechanism of Inflammation.
Rajpoot S, Wary KK, Ibbott R, Liu D, Saqib U, Thurston TLM, Baig MS. Rajpoot S, et al. Front Immunol. 2021 Jul 8;12:697588. doi: 10.3389/fimmu.2021.697588. eCollection 2021. Front Immunol. 2021. PMID: 34305934 Free PMC article. Review.
Subsequent studies delineated TIRAP's role as a transducer of signalling events through its interaction with non-TLR signalling mediators. Indeed, the ability of TIRAP to interact with an array of intracellular signalling mediators suggests its central role in vario …
Subsequent studies delineated TIRAP's role as a transducer of signalling events through its interaction with non-TLR signalling media …
TLR signaling pathways.
Takeda K, Akira S. Takeda K, et al. Semin Immunol. 2004 Feb;16(1):3-9. doi: 10.1016/j.smim.2003.10.003. Semin Immunol. 2004. PMID: 14751757 Review.
Recent accumulating evidence has demonstrated that TIR domain-containing adaptors, such as MyD88, TIRAP, and TRIF, modulate TLR signaling pathways. MyD88 is essential for the induction of inflammatory cytokines triggered by all TLRs. TIRAP is specifically involved i …
Recent accumulating evidence has demonstrated that TIR domain-containing adaptors, such as MyD88, TIRAP, and TRIF, modulate TLR signa …
TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling.
Ciesielska A, Matyjek M, Kwiatkowska K. Ciesielska A, et al. Cell Mol Life Sci. 2021 Feb;78(4):1233-1261. doi: 10.1007/s00018-020-03656-y. Epub 2020 Oct 15. Cell Mol Life Sci. 2021. PMID: 33057840 Free PMC article. Review.
TLR4 is activated by lipopolysaccharide (LPS, endotoxin) of Gram-negative bacteria and sequentially triggers two signaling cascades: the first one involving TIRAP and MyD88 adaptor proteins is induced in the plasma membrane, whereas the second engaging adaptor proteins TRA …
TLR4 is activated by lipopolysaccharide (LPS, endotoxin) of Gram-negative bacteria and sequentially triggers two signaling cascades: the fir …
Tirap controls Mycobacterium tuberculosis phagosomal acidification.
Belhaouane I, Pochet A, Chatagnon J, Hoffmann E, Queval CJ, Deboosère N, Boidin-Wichlacz C, Majlessi L, Sencio V, Heumel S, Vandeputte A, Werkmeister E, Fievez L, Bureau F, Rouillé Y, Trottein F, Chamaillard M, Brodin P, Machelart A. Belhaouane I, et al. PLoS Pathog. 2023 Mar 8;19(3):e1011192. doi: 10.1371/journal.ppat.1011192. eCollection 2023 Mar. PLoS Pathog. 2023. PMID: 36888688 Free PMC article.
Interestingly, compared to wild type littermates, Tirap heterozygous mice were more resistant to Mtb infection. Upon investigation at the cellular level, we observed that mycobacteria were not able to replicate in Tirap-deficient macrophages compared to wild type co …
Interestingly, compared to wild type littermates, Tirap heterozygous mice were more resistant to Mtb infection. Upon investigation at …
TIRAP, TRAM, and Toll-Like Receptors: The Untold Story.
Lannoy V, Côté-Biron A, Asselin C, Rivard N. Lannoy V, et al. Mediators Inflamm. 2023 Mar 7;2023:2899271. doi: 10.1155/2023/2899271. eCollection 2023. Mediators Inflamm. 2023. PMID: 36926280 Free PMC article. Review.
In this review, we highlight important results demonstrating that TIRAP and TRAM adaptors are also required for full signaling activity and responses induced by most TLRs....
In this review, we highlight important results demonstrating that TIRAP and TRAM adaptors are also required for full signaling activi …
Paradoxical Roles of the MAL/Tirap Adaptor in Pathologies.
Belhaouane I, Hoffmann E, Chamaillard M, Brodin P, Machelart A. Belhaouane I, et al. Front Immunol. 2020 Sep 25;11:569127. doi: 10.3389/fimmu.2020.569127. eCollection 2020. Front Immunol. 2020. PMID: 33072109 Free PMC article. Review.
Among these, Toll/Interleukin-1 receptor domain containing adaptor protein (Tirap or MAL) plays an important role in establishing immune responses. ...
Among these, Toll/Interleukin-1 receptor domain containing adaptor protein (Tirap or MAL) plays an important role in establishing imm …
TIRAP-mediated activation of p38 MAPK in inflammatory signaling.
Rajpoot S, Kumar A, Zhang KYJ, Gan SH, Baig MS. Rajpoot S, et al. Sci Rep. 2022 Apr 4;12(1):5601. doi: 10.1038/s41598-022-09528-8. Sci Rep. 2022. PMID: 35379857 Free PMC article.
The objective of this study is to understand the interaction of TIRAP with p38 MAPK through molecular docking and identify the importance of TIRAP tyrosine phosphorylation in p38 MAPK interaction. ...The heatmap of interactions between the TIRAP and p38 MAPK …
The objective of this study is to understand the interaction of TIRAP with p38 MAPK through molecular docking and identify the import …
A Leak in the Dike.
Egesten A, Herwald H. Egesten A, et al. J Innate Immun. 2020;12(5):355-356. doi: 10.1159/000510316. Epub 2020 Aug 20. J Innate Immun. 2020. PMID: 32818941 Free PMC article. No abstract available.
ALKBH5-mediated m(6) A demethylation of TIRAP mRNA promotes radiation-induced liver fibrosis and decreases radiosensitivity of hepatocellular carcinoma.
Chen Y, Zhou P, Deng Y, Cai X, Sun M, Sun Y, Wu D. Chen Y, et al. Clin Transl Med. 2023 Feb;13(2):e1198. doi: 10.1002/ctm2.1198. Clin Transl Med. 2023. PMID: 36792369 Free PMC article.
RESULTS: Radiation-induced ALKBH5 expression in HSC mediated m(6) A demethylation of toll-interleukin 1 receptor domain containing adaptor protein (TIRAP) mRNA and activated its downstream NF-kappaB and JNK/Smad2 pathways to promote HSC activation. ...HCC patients with hig …
RESULTS: Radiation-induced ALKBH5 expression in HSC mediated m(6) A demethylation of toll-interleukin 1 receptor domain containing adaptor p …
Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell-type specific manner that are altered in inflammatory bowel disease.
Gul L, Modos D, Fonseca S, Madgwick M, Thomas JP, Sudhakar P, Booth C, Stentz R, Carding SR, Korcsmaros T. Gul L, et al. J Extracell Vesicles. 2022 Jan;11(1):e12189. doi: 10.1002/jev2.12189. J Extracell Vesicles. 2022. PMID: 35064769 Free PMC article.
The in silico findings were validated in BEV-monocyte co-cultures demonstrating the requirement for TLR4 and Toll-interleukin-1 receptor domain-containing adaptor protein (TIRAP) in BEV-elicited NF-kB activation. This study demonstrates that both cell-type and health statu …
The in silico findings were validated in BEV-monocyte co-cultures demonstrating the requirement for TLR4 and Toll-interleukin-1 receptor dom …
642 results