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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
1998 6
1999 1
2000 6
2001 2
2002 4
2003 4
2004 4
2005 9
2006 2
2007 8
2008 4
2009 6
2010 7
2011 5
2012 6
2013 12
2014 14
2015 14
2016 20
2017 25
2018 20
2019 24
2020 24
2021 27
2022 27
2023 27
2024 14

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290 results

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Page 1
CrossFit Overview: Systematic Review and Meta-analysis.
Claudino JG, Gabbett TJ, Bourgeois F, Souza HS, Miranda RC, Mezêncio B, Soncin R, Cardoso Filho CA, Bottaro M, Hernandez AJ, Amadio AC, Serrão JC. Claudino JG, et al. Sports Med Open. 2018 Feb 26;4(1):11. doi: 10.1186/s40798-018-0124-5. Sports Med Open. 2018. PMID: 29484512 Free PMC article. Review.
However, preliminary data has suggested that CrossFit practice is associated with higher levels of sense of community, satisfaction, and motivation....
However, preliminary data has suggested that CrossFit practice is associated with higher levels of sense of community, satisfaction, …
The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake.
de Mingo Pulido Á, Hänggi K, Celias DP, Gardner A, Li J, Batista-Bittencourt B, Mohamed E, Trillo-Tinoco J, Osunmakinde O, Peña R, Onimus A, Kaisho T, Kaufmann J, McEachern K, Soliman H, Luca VC, Rodriguez PC, Yu X, Ruffell B. de Mingo Pulido Á, et al. Immunity. 2021 Jun 8;54(6):1154-1167.e7. doi: 10.1016/j.immuni.2021.04.019. Epub 2021 May 11. Immunity. 2021. PMID: 33979578 Free PMC article.
DNA uptake and efficacy of TIM-3 blockade required DNA binding by HMGB1, while galectin-9-induced cell surface clustering of TIM-3 was necessary for its suppressive function. Human peripheral blood cDC1s also took up extracellular DNA upon TIM-3 blockade. Thu …
DNA uptake and efficacy of TIM-3 blockade required DNA binding by HMGB1, while galectin-9-induced cell surface clustering of TIM …
Cryptochrome-Timeless structure reveals circadian clock timing mechanisms.
Lin C, Feng S, DeOliveira CC, Crane BR. Lin C, et al. Nature. 2023 May;617(7959):194-199. doi: 10.1038/s41586-023-06009-4. Epub 2023 Apr 26. Nature. 2023. PMID: 37100907
Here, through cryogenic electron microscopy of the Cry-Tim complex, we show how a light-sensing cryptochrome recognizes its target. Cry engages a continuous core of amino-terminal Tim armadillo repeats, resembling how photolyases recognize damaged DNA, and bi …
Here, through cryogenic electron microscopy of the Cry-Tim complex, we show how a light-sensing cryptochrome recognizes its ta …
PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity.
Liu J, Bu X, Chu C, Dai X, Asara JM, Sicinski P, Freeman GJ, Wei W. Liu J, et al. Nat Commun. 2023 May 17;14(1):2806. doi: 10.1038/s41467-023-38443-3. Nat Commun. 2023. PMID: 37193698 Free PMC article.
Notably, genetic or pharmaceutical ablation of PRMT1 leads to activation of cGAS/STING-dependent DNA sensing signaling, and robustly elevates the transcription of type I and II interferon response genes. ...
Notably, genetic or pharmaceutical ablation of PRMT1 leads to activation of cGAS/STING-dependent DNA sensing signaling, and robustly …
A Comprehensive Review of Hepatic Hemangioma Management.
Aziz H, Brown ZJ, Baghdadi A, Kamel IR, Pawlik TM. Aziz H, et al. J Gastrointest Surg. 2022 Sep;26(9):1998-2007. doi: 10.1007/s11605-022-05382-1. Epub 2022 Jun 15. J Gastrointest Surg. 2022. PMID: 35705835 Review.
Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function.
Tang R, Acharya N, Subramanian A, Purohit V, Tabaka M, Hou Y, He D, Dixon KO, Lambden C, Xia J, Rozenblatt-Rosen O, Sobel RA, Wang C, Regev A, Anderson AC, Kuchroo VK. Tang R, et al. Sci Immunol. 2022 Mar 11;7(69):eabm0631. doi: 10.1126/sciimmunol.abm0631. Epub 2022 Mar 11. Sci Immunol. 2022. PMID: 35275752 Free PMC article.
Dendritic cells (DCs) sense environmental cues and adopt either an immune-stimulatory or regulatory phenotype, thereby fine-tuning immune responses. ...Bat3 is an adaptor protein that binds to the tail of Tim-3; therefore, we studied its role in regulating the funct …
Dendritic cells (DCs) sense environmental cues and adopt either an immune-stimulatory or regulatory phenotype, thereby fine-tuning im …
Checkpoint Receptor TIGIT Expressed on Tim-1(+) B Cells Regulates Tissue Inflammation.
Xiao S, Bod L, Pochet N, Kota SB, Hu D, Madi A, Kilpatrick J, Shi J, Ho A, Zhang H, Sobel R, Weiner HL, Strom TB, Quintana FJ, Joller N, Kuchroo VK. Xiao S, et al. Cell Rep. 2020 Jul 14;32(2):107892. doi: 10.1016/j.celrep.2020.107892. Cell Rep. 2020. PMID: 32668241 Free PMC article.
Tim-1, a phosphatidylserine receptor expressed on B cells, induces interleukin 10 (IL-10) production by sensing apoptotic cells. ...Transcriptomic analysis demonstrates that besides IL-10, Tim-1(+) B cells also differentially express a number of co-inhibitory …
Tim-1, a phosphatidylserine receptor expressed on B cells, induces interleukin 10 (IL-10) production by sensing apoptotic cell …
Membrane lipid compositional sensing by the inducible amphipathic helix of CCT.
Cornell RB. Cornell RB. Biochim Biophys Acta. 2016 Aug;1861(8 Pt B):847-861. doi: 10.1016/j.bbalip.2015.12.022. Epub 2015 Dec 31. Biochim Biophys Acta. 2016. PMID: 26747646 Review.
The amphipathic helical (AH) membrane binding motif is recognized as a major device for lipid compositional sensing. We explore the function and mechanism of sensing by the lipid biosynthetic enzyme, CTP:phosphocholine cytidylyltransferase (CCT). ...This article is …
The amphipathic helical (AH) membrane binding motif is recognized as a major device for lipid compositional sensing. We explore the f …
Disuse Osteoporosis: Clinical and Mechanistic Insights.
Rolvien T, Amling M. Rolvien T, et al. Calcif Tissue Int. 2022 May;110(5):592-604. doi: 10.1007/s00223-021-00836-1. Epub 2021 Mar 18. Calcif Tissue Int. 2022. PMID: 33738515 Free PMC article. Review.
Furthermore, molecular-based in vitro and in vivo approaches have revealed that osteocytes sense mechanical loading through mechanosensors that translate extracellular mechanical signals to intracellular biochemical signals and regulate gene expression. ...
Furthermore, molecular-based in vitro and in vivo approaches have revealed that osteocytes sense mechanical loading through mechanose …
Sensing membrane thickness: Lessons learned from cold stress.
Saita E, Albanesi D, de Mendoza D. Saita E, et al. Biochim Biophys Acta. 2016 Aug;1861(8 Pt B):837-846. doi: 10.1016/j.bbalip.2016.01.003. Epub 2016 Jan 8. Biochim Biophys Acta. 2016. PMID: 26776056 Review.
As a consequence, nature has evolved proteins that are able to sense changes in the bilayer properties and transform these lipid-mediated stimuli into intracellular signals. ...This article is part of a Special Issue entitled: The cellular lipid landscape edited by Tim …
As a consequence, nature has evolved proteins that are able to sense changes in the bilayer properties and transform these lipid-medi …
290 results