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Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators. Salloway S, et al. N Engl J Med. 2014 Jan 23;370(4):322-33. doi: 10.1056/NEJMoa1304839. N Engl J Med. 2014. PMID: 24450891 Free PMC article. Clinical Trial.
Secondary outcome measures included findings on positron-emission tomographic amyloid imaging with the use of Pittsburgh compound B (PIB-PET) and cerebrospinal fluid phosphorylated tau (phospho-tau) concentrations. ...
Secondary outcome measures included findings on positron-emission tomographic amyloid imaging with the use of Pittsburgh compound B ( …
25th Annual Computational Neuroscience Meeting: CNS-2016.
Sharpee TO, Destexhe A, Kawato M, Sekulić V, Skinner FK, Wójcik DK, Chintaluri C, Cserpán D, Somogyvári Z, Kim JK, Kilpatrick ZP, Bennett MR, Josić K, Elices I, Arroyo D, Levi R, Rodriguez FB, Varona P, Hwang E, Kim B, Han HB, Kim T, McKenna JT, Brown RE, McCarley RW, Choi JH, Rankin J, Popp PO, Rinzel J, Tabas A, Rupp A, Balaguer-Ballester E, Maturana MI, Grayden DB, Cloherty SL, Kameneva T, Ibbotson MR, Meffin H, Koren V, Lochmann T, Dragoi V, Obermayer K, Psarrou M, Schilstra M, Davey N, Torben-Nielsen B, Steuber V, Ju H, Yu J, Hines ML, Chen L, Yu Y, Kim J, Leahy W, Shlizerman E, Birgiolas J, Gerkin RC, Crook SM, Viriyopase A, Memmesheimer RM, Gielen S, Dabaghian Y, DeVito J, Perotti L, Kim AJ, Fenk LM, Cheng C, Maimon G, Zhao C, Widmer Y, Sprecher S, Senn W, Halnes G, Mäki-Marttunen T, Keller D, Pettersen KH, Andreassen OA, Einevoll GT, Yamada Y, Steyn-Ross ML, Alistair Steyn-Ross D, Mejias JF, Murray JD, Kennedy H, Wang XJ, Kruscha A, Grewe J, Benda J, Lindner B, Badel L, Ohta K, Tsuchimoto Y, Kazama H, Kahng B, Tam ND, Pollonini L, Zouridakis G, Soh J, Kim D, Yoo M, Palmer SE, Culmone V, Bojak I, Ferrario A, Merrison-Hort R, Borisyuk R, Kim CS, Tezuka T, Joo P, Rho YA, Burt… See abstract for full author list ➔ Sharpee TO, et al. BMC Neurosci. 2016 Aug 18;17 Suppl 1(Suppl 1):54. doi: 10.1186/s12868-016-0283-6. BMC Neurosci. 2016. PMID: 27534393 Free PMC article.
Petrovici, Luziwei Leng, Oliver Breitwieser, David Stockel, Ilja Bytschok, Roman Martel, Johannes Bill, Johannes Schemmel, Karlheinz Meier P97 Modeling orientation-selective electrical stimulation with retinal prostheses Timothy B. Esler, Anthony N. Burkitt, David B …
Petrovici, Luziwei Leng, Oliver Breitwieser, David Stockel, Ilja Bytschok, Roman Martel, Johannes Bill, Johannes Schemmel, Karlheinz Meier P …
Function of surfactant proteins B and C.
Weaver TE, Conkright JJ. Weaver TE, et al. Annu Rev Physiol. 2001;63:555-78. doi: 10.1146/annurev.physiol.63.1.555. Annu Rev Physiol. 2001. PMID: 11181967 Review.
SP-B is the only surfactant-associated protein absolutely required for postnatal lung function and survival. ...This review attempts to integrate recent findings in humans and transgenic mice with the results of in vitro studies to provide a better understanding of the fun …
SP-B is the only surfactant-associated protein absolutely required for postnatal lung function and survival. ...This review attempts …
Use of knockout mice to study surfactant protein structure and function.
Weaver TE, Beck DC. Weaver TE, et al. Biol Neonate. 1999 Jun;76 Suppl 1:15-8. doi: 10.1159/000047041. Biol Neonate. 1999. PMID: 10393388 Review.
Pulmonary surfactant protein B (SP-B) is a 79 amino acid peptide that is intimately associated with surfactant phospholipids in the alveolar airspace. Mutations of the SP-B gene that result in complete absence of SP-B are invariably fatal in the neonat …
Pulmonary surfactant protein B (SP-B) is a 79 amino acid peptide that is intimately associated with surfactant phospholipids i …
Biogenesis of lamellar bodies, lysosome-related organelles involved in storage and secretion of pulmonary surfactant.
Weaver TE, Na CL, Stahlman M. Weaver TE, et al. Semin Cell Dev Biol. 2002 Aug;13(4):263-70. doi: 10.1016/s1084952102000551. Semin Cell Dev Biol. 2002. PMID: 12243725 Review.
The principal constituents of the lamellar body, surfactant phospholipids, are organized into tightly packed, bilayer membranes in a process that is strongly influenced by the lung-specific, hydrophobic peptide SP-B. Newly synthesized SP-B is transported from the Go …
The principal constituents of the lamellar body, surfactant phospholipids, are organized into tightly packed, bilayer membranes in a process …
Synthesis, processing and secretion of surfactant proteins B and C.
Weaver TE. Weaver TE. Biochim Biophys Acta. 1998 Nov 19;1408(2-3):173-9. doi: 10.1016/s0925-4439(98)00066-0. Biochim Biophys Acta. 1998. PMID: 9813310 Free article. Review.
Two small, hydrophobic peptides, surfactant protein (SP)-B and SP-C, play important roles in the generation and maintenance of a surface active film in the alveolus. ...The biosynthetic pathway leading to generation and secretion of the biophysically active mature SP-B …
Two small, hydrophobic peptides, surfactant protein (SP)-B and SP-C, play important roles in the generation and maintenance of a surf …